Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GQY29_RS09890 Genome accession   NZ_CP047191
Coordinates   1885015..1887273 (+) Length   752 a.a.
NCBI ID   WP_159341107.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain EU01     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1880015..1892273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQY29_RS09865 (GQY29_09865) - 1881158..1881634 (-) 477 WP_014608118.1 ferrous iron transport protein A -
  GQY29_RS09870 (GQY29_09870) - 1881808..1882542 (-) 735 WP_011225688.1 amino acid ABC transporter ATP-binding protein -
  GQY29_RS09875 (GQY29_09875) - 1882542..1883222 (-) 681 WP_014608117.1 amino acid ABC transporter permease -
  GQY29_RS09880 (GQY29_09880) - 1883495..1883725 (-) 231 WP_011225686.1 DUF1797 family protein -
  GQY29_RS09885 (GQY29_09885) argF 1883794..1884774 (-) 981 WP_014608116.1 ornithine carbamoyltransferase -
  GQY29_RS09890 (GQY29_09890) clpE 1885015..1887273 (+) 2259 WP_159341107.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GQY29_RS09895 (GQY29_09895) - 1887416..1887874 (+) 459 WP_002947302.1 NUDIX hydrolase -
  GQY29_RS09900 (GQY29_09900) - 1887884..1888186 (+) 303 WP_014608115.1 DUF1827 family protein -
  GQY29_RS09905 (GQY29_09905) - 1888227..1889190 (-) 964 Protein_1860 Gfo/Idh/MocA family oxidoreductase -
  GQY29_RS09910 (GQY29_09910) - 1889289..1890524 (-) 1236 WP_014608114.1 aminoacyltransferase -
  GQY29_RS09915 (GQY29_09915) - 1890502..1891044 (-) 543 WP_014621342.1 VTT domain-containing protein -
  GQY29_RS09920 (GQY29_09920) - 1891257..1891877 (-) 621 WP_023909511.1 DUF3862 domain-containing protein -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83806.90 Da        Isoelectric Point: 5.1506

>NTDB_id=411419 GQY29_RS09890 WP_159341107.1 1885015..1887273(+) (clpE) [Streptococcus thermophilus strain EU01]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQSPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKDF
KAVMTSKGHITIKSAQKTEKTSQKTEALKEVN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=411419 GQY29_RS09890 WP_159341107.1 1885015..1887273(+) (clpE) [Streptococcus thermophilus strain EU01]
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAACGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACGTCAACAATCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATTTGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTGCTTCACATGTTCCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATGCCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATTTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTCAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(644-717)

ATPase family associated with various cellular activities (AAA) (AAA)

(150-269)

AAA domain (Cdc48 subfamily) (AAA_2)

(473-636)

AAA lid domain (AAA_lid_9)

(288-386)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.288

99.867

0.842
  clpE Streptococcus pneumoniae Rx1

81.915

100

0.819
  clpE Streptococcus pneumoniae D39

81.915

100

0.819
  clpE Streptococcus pneumoniae R6

81.915

100

0.819
  clpE Streptococcus pneumoniae TIGR4

81.782

100

0.818
  clpC Lactococcus lactis subsp. cremoris KW2

76.502

99.601

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

51.772

86.303

0.447
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

45.884

87.234

0.4
  clpC Streptococcus pneumoniae Rx1

46.984

83.777

0.394
  clpC Streptococcus pneumoniae D39

46.984

83.777

0.394
  clpC Streptococcus pneumoniae TIGR4

46.825

83.777

0.392
  clpC Streptococcus mutans UA159

46.326

83.245

0.386
  clpC Streptococcus thermophilus LMD-9

46.4

83.112

0.386
  clpC Streptococcus thermophilus LMG 18311

46.08

83.112

0.383

Multiple sequence alignment