Detailed information NTG0410985

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: H3M14_RS10145
• Genome accession: NZ_CP059697
• Coordinates: 1969666..1972269 (-)
• Length: 867 a.a.
• NCBI ID: WP_016264638.1
• Uniprot ID: -
• Organism: Latilactobacillus sakei strain CBA3635
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1964666..1977269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H3M14_RS10120 (H3M14_10120)	ruvB	1964678..1965685 (-)	1008	WP_016264643.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
H3M14_RS10125 (H3M14_10125)	ruvA	1965698..1966309 (-)	612	WP_016264642.1	Holliday junction branch migration protein RuvA	Machinery gene
H3M14_RS10130 (H3M14_10130)	-	1966560..1967120 (-)	561	WP_182159999.1	TIGR00730 family Rossman fold protein	-
H3M14_RS10135 (H3M14_10135)	-	1967136..1967681 (-)	546	WP_016264640.1	nucleoside triphosphate pyrophosphatase	-
H3M14_RS10140 (H3M14_10140)	hexB	1967681..1969642 (-)	1962	WP_182160002.1	DNA mismatch repair endonuclease MutL	Machinery gene
H3M14_RS10145 (H3M14_10145)	hexA	1969666..1972269 (-)	2604	WP_016264638.1	DNA mismatch repair protein MutS	Machinery gene
H3M14_RS10150 (H3M14_10150)	-	1972291..1973097 (-)	807	WP_016264637.1	TIGR00282 family metallophosphoesterase	-
H3M14_RS10155 (H3M14_10155)	-	1973274..1975103 (-)	1830	WP_016264636.1	APC family permease	-

Sequence

Protein

• Length: 867 a.a.
• Molecular weight: 96876.71 Da
• Isoelectric Point: 5.2556

>NTDB_id=410985 H3M14_RS10145 WP_016264638.1 1969666..1972269(-) (hexA) [Latilactobacillus sakei strain CBA3635]
MPQKTKETPMMAQYQKVKDQYPDAFLFYRLGDFYELFNDDAVKASQLLELTLTARNKNAADPIPMCGVPHHAAQNYIDIL
VDQGYKVAICEQMEDPKTAKGMVKREVVQLVTPGTVMDEKAGHAKQNNYLTAVVAQGDQFGFAYTDLSTGEMKVSQISSL
DVLLNEMLSLQTKEVVVNHDVPSEVVQAFVQQQILVSYQDEGADTAEVSFVSQNISQPLALAVIKQLVVYLATTQKRHLG
HLQRAQAYEPSQYLKLDHSAKMNLELTASLRTGHKSGTLLWLLDETKTAMGGRLLKQWLERPLLDLNQIKNRQNQVASFL
QHYFERTNLQEALTKVYDLERLAGRVAFGSVNGRDLIQLKTSLEQIPKIKDVLTGINETQAFDQALTRLDPVDDVRTLIE
TAINPDSPISVTDGGIIQDGYDEQLDQYRNAMSNGKQWLAQLEAQEREATGIHNLKIGFNRVFGYYIEVTRANLSSLPEG
RYERKQTLTNAERFITPELKEKEQLILEAEERSTALEYELFTQVREQVKLQIERLQTLAKGVAALDVLQSFAVVSESYHY
VQPTLRTDSREIDLVDGRHPVVEKVLGRQKYIPNAVQMGKETDMLLITGPNMSGKSTYMRQLALTVIMAQMGCFVPAKSA
NLPVFDQIFTRIGAADDLISGQSTFMVEMMEANRAIMSATANSLILFDEIGRGTATYDGMALAQAIIEYIHDHVHAKTLF
STHYHELTALADTLTALRNVHVGAVEENGELVFLHKMLAGPADKSYGIHVAKLAGMPETLLQRADVILGQLEDKPKAPVQ
PEIVVPAQPTAAAVEEQMALFEPEVAAPVDKKTDKVVAAIKNFDLMSATPLEALNQLYEWQKQLNKH

Nucleotide

• Length: 2604 bp

>NTDB_id=410985 H3M14_RS10145 WP_016264638.1 1969666..1972269(-) (hexA) [Latilactobacillus sakei strain CBA3635]
ATGCCGCAAAAAACAAAAGAAACGCCAATGATGGCCCAATATCAAAAGGTTAAGGATCAATATCCAGACGCCTTTTTATT
TTATAGATTGGGTGATTTTTACGAATTATTCAATGATGATGCTGTTAAAGCATCACAACTTTTAGAATTAACGCTGACAG
CGCGTAATAAGAATGCAGCAGACCCCATTCCGATGTGTGGTGTGCCCCATCATGCAGCGCAAAACTACATTGATATTTTA
GTGGATCAAGGTTACAAGGTCGCCATTTGTGAGCAGATGGAAGATCCTAAAACGGCTAAGGGCATGGTCAAACGCGAAGT
TGTCCAATTAGTAACACCTGGGACCGTGATGGACGAAAAAGCCGGTCACGCTAAACAAAATAATTATTTAACGGCAGTCG
TTGCACAAGGCGATCAATTTGGCTTTGCCTATACGGATTTATCCACAGGTGAAATGAAGGTTAGCCAAATCAGTAGTTTA
GATGTGTTATTAAACGAAATGTTGAGTTTACAAACCAAAGAAGTGGTTGTGAACCATGATGTCCCAAGCGAAGTCGTTCA
AGCCTTTGTCCAACAACAAATCTTGGTTTCTTATCAAGATGAGGGGGCCGATACGGCAGAGGTCAGTTTTGTTTCTCAAA
ATATCTCACAACCACTAGCATTAGCCGTCATTAAACAGTTAGTTGTTTATTTAGCAACGACGCAAAAGCGGCACTTGGGC
CATTTACAACGCGCCCAAGCCTATGAACCTTCTCAATACTTGAAGTTGGATCATTCGGCTAAGATGAACCTCGAATTAAC
GGCTTCATTACGAACTGGCCATAAGAGTGGGACGTTATTGTGGCTACTGGATGAAACAAAGACTGCGATGGGTGGTCGTT
TATTAAAACAATGGTTGGAACGACCATTGTTGGATTTAAACCAGATTAAGAACCGGCAAAACCAAGTCGCTAGTTTCTTA
CAGCACTATTTTGAAAGGACGAACCTTCAAGAAGCCCTAACCAAGGTTTATGATTTGGAACGTCTAGCGGGTCGCGTTGC
TTTTGGGAGCGTTAATGGTCGCGATTTGATTCAATTAAAAACATCCTTAGAACAGATTCCAAAGATTAAAGATGTTTTGA
CGGGCATTAACGAAACGCAGGCTTTTGATCAAGCGTTAACGCGTTTGGATCCAGTTGATGATGTGCGGACGTTAATTGAA
ACAGCGATTAACCCGGATTCACCGATTTCAGTGACTGATGGCGGGATTATTCAAGATGGTTACGACGAACAACTTGATCA
ATACCGCAATGCGATGTCTAACGGCAAGCAGTGGTTGGCGCAATTAGAGGCGCAAGAACGAGAAGCCACGGGCATTCATA
ATTTGAAAATCGGCTTTAACCGCGTCTTTGGGTATTATATCGAAGTCACGCGGGCTAACTTGAGTTCATTACCGGAAGGG
CGGTATGAACGCAAACAAACGTTAACCAACGCCGAACGATTCATCACACCGGAACTAAAAGAAAAAGAACAACTGATTTT
AGAGGCGGAAGAACGCTCAACCGCTTTAGAATACGAATTGTTTACCCAAGTTCGGGAACAAGTGAAGTTACAGATTGAAC
GGCTCCAAACATTGGCTAAAGGCGTAGCGGCCCTAGATGTCTTGCAAAGTTTTGCGGTCGTCAGCGAAAGCTACCACTAT
GTCCAACCAACATTAAGAACTGATAGTCGCGAAATTGATTTAGTCGATGGCCGTCATCCGGTGGTTGAAAAGGTATTGGG
ACGCCAAAAATATATCCCCAATGCTGTTCAAATGGGCAAAGAAACGGATATGTTATTAATTACCGGACCTAATATGTCTG
GTAAAAGTACCTACATGCGGCAATTGGCCTTAACGGTCATCATGGCGCAAATGGGTTGTTTTGTACCTGCCAAGTCAGCG
AACTTGCCTGTATTTGATCAAATTTTTACCCGCATTGGCGCGGCAGATGATTTGATTTCAGGACAAAGTACGTTTATGGT
AGAAATGATGGAAGCCAACCGTGCAATTATGAGTGCGACCGCCAATAGTTTAATTCTTTTCGATGAAATTGGTCGGGGAA
CGGCAACTTACGATGGAATGGCCTTGGCACAAGCGATTATCGAATATATCCATGATCACGTCCACGCCAAGACGCTCTTT
TCAACGCATTATCATGAATTGACGGCTTTAGCCGATACGTTGACCGCCCTTCGTAACGTGCATGTTGGTGCGGTTGAGGA
AAACGGCGAGTTGGTCTTCTTACACAAGATGTTGGCCGGACCTGCGGATAAGTCTTACGGGATTCATGTCGCTAAACTAG
CGGGCATGCCAGAAACCTTATTACAACGGGCCGATGTTATTTTAGGTCAGTTAGAAGATAAACCAAAAGCACCGGTGCAA
CCAGAAATAGTCGTACCAGCACAACCGACTGCAGCGGCTGTCGAAGAACAGATGGCGCTTTTTGAACCAGAAGTGGCGGC
CCCGGTCGATAAGAAAACAGATAAAGTGGTAGCGGCAATTAAGAATTTTGATTTGATGAGCGCCACACCACTAGAAGCCC
TCAATCAATTATATGAGTGGCAAAAGCAATTAAATAAACATTAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-119)

• MutS domain II (MutS_II) (128-243)

• MutS family domain IV (MutS_IV) (420-512)

• MutS domain V (MutS_V) (605-792)

• MutS domain III (MutS_III) (263-552)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	52.079	99.885	0.52
mutS	Pseudomonas stutzeri strain ATCC 17587	38.655	100	0.391