Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GE573_RS15600 Genome accession   NZ_CP047119
Coordinates   3037044..3037700 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain AK-0     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3032044..3042700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE573_RS15570 (GE573_03110) oppF 3032575..3033492 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  GE573_RS15575 (GE573_03111) - 3033598..3034785 (+) 1188 WP_015239569.1 putative glycoside hydrolase -
  GE573_RS15580 (GE573_03112) - 3034903..3035481 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  GE573_RS15585 (GE573_03113) spx 3035660..3036055 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  GE573_RS15590 (GE573_03114) - 3036112..3036768 (-) 657 WP_007409109.1 TerC family protein -
  GE573_RS19770 - 3036951..3037061 (+) 111 Protein_3034 adaptor protein MecA -
  GE573_RS15600 (GE573_03115) mecA 3037044..3037700 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  GE573_RS15605 (GE573_03116) - 3037852..3039012 (+) 1161 WP_063095693.1 competence protein CoiA family protein -
  GE573_RS15610 (GE573_03117) pepF 3039240..3041069 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  GE573_RS15615 (GE573_03118) - 3041107..3041274 (-) 168 WP_003155026.1 hypothetical protein -
  GE573_RS15620 (GE573_03119) spxH 3041562..3042464 (-) 903 WP_039251990.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=410702 GE573_RS15600 WP_003155032.1 3037044..3037700(+) (mecA) [Bacillus velezensis strain AK-0]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=410702 GE573_RS15600 WP_003155032.1 3037044..3037700(+) (mecA) [Bacillus velezensis strain AK-0]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment