Detailed information NTG0409909

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: GQX63_RS09580
• Genome accession: NZ_CP047021
• Coordinates: 1959484..1960527 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain M2024
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1954484..1965527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQX63_RS09550 (GQX63_09560)	-	1954906..1956162 (-)	1257	WP_001793428.1	aminopeptidase	-
GQX63_RS09555 (GQX63_09565)	-	1956165..1956365 (-)	201	WP_000180460.1	DUF1128 family protein	-
GQX63_RS09560 (GQX63_09570)	-	1956512..1956976 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
GQX63_RS09565 (GQX63_09575)	-	1956983..1957258 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
GQX63_RS09570 (GQX63_09580)	-	1957536..1958753 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
GQX63_RS09575 (GQX63_09585)	vraR	1958865..1959494 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
GQX63_RS09580 (GQX63_09590)	vraS	1959484..1960527 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
GQX63_RS09585 (GQX63_09595)	liaF	1960524..1961225 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
GQX63_RS09590 (GQX63_09600)	-	1961240..1961626 (-)	387	WP_001110179.1	hypothetical protein	-
GQX63_RS09595 (GQX63_09605)	map	1961843..1962601 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
GQX63_RS09600 (GQX63_09610)	-	1963132..1964118 (+)	987	WP_000999716.1	aromatic acid exporter family protein	-
GQX63_RS09605 (GQX63_09615)	-	1964608..1965021 (-)	414	WP_001670387.1	hypothetical protein	-
GQX63_RS09610 (GQX63_09620)	-	1965050..1965160 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=409909 GQX63_RS09580 WP_001017131.1 1959484..1960527(-) (vraS) [Staphylococcus aureus strain M2024]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=409909 GQX63_RS09580 WP_001017131.1 1959484..1960527(-) (vraS) [Staphylococcus aureus strain M2024]
ATGAACCATTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1