Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GPZ88_RS09190 Genome accession   NZ_CP046919
Coordinates   1811820..1813148 (-) Length   442 a.a.
NCBI ID   WP_039696862.1    Uniprot ID   A0A091BVP1
Organism   Streptococcus ruminicola strain CNU_G2     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1806820..1818148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS09165 (GPZ88_09140) - 1807338..1808402 (-) 1065 WP_166044198.1 BMP family lipoprotein -
  GPZ88_RS09170 (GPZ88_09145) deoC 1808596..1809261 (-) 666 WP_074625712.1 deoxyribose-phosphate aldolase -
  GPZ88_RS09175 (GPZ88_09150) - 1809763..1810356 (-) 594 WP_157629041.1 class I SAM-dependent methyltransferase -
  GPZ88_RS09180 (GPZ88_09155) coaA 1810488..1811408 (+) 921 WP_157629042.1 type I pantothenate kinase -
  GPZ88_RS09185 (GPZ88_09160) rpsT 1811484..1811735 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  GPZ88_RS09190 (GPZ88_09165) ciaH 1811820..1813148 (-) 1329 WP_039696862.1 sensor histidine kinase Regulator
  GPZ88_RS09195 (GPZ88_09170) ciaR 1813138..1813812 (-) 675 WP_074563738.1 response regulator transcription factor Regulator
  GPZ88_RS09200 (GPZ88_09175) - 1813979..1816522 (-) 2544 WP_157629043.1 M1 family metallopeptidase -
  GPZ88_RS09205 (GPZ88_09180) phoU 1816753..1817406 (-) 654 WP_039696860.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 50098.00 Da        Isoelectric Point: 6.6262

>NTDB_id=409454 GPZ88_RS09190 WP_039696862.1 1811820..1813148(-) (ciaH) [Streptococcus ruminicola strain CNU_G2]
MLNNIHKKLSTGTFSNFFHFFIVFTGIFIIMTTIILQIMRYGLYSSVDTTLKNAADNASDYVTRTMERSDSLQSNNSFSN
SGKGKPSSNVASLSNVSVLLYDTNGKIVNAIDAFVQFGTLASSVDEDTIGEIKDEKMTTIFGQTEKYHVLTVRVYSSDYP
TIEYATFLISVSQLDEANERYVTITVSVMIIFWMISILASIYLANWMRKPILESYEKQKRFVENASHELRTPLAVLQNRL
ESLFRRPNATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIQPSIFNEIFENYNMIAEENGKTFVAHNS
ADRPIKTDRTLLKQLMTILFDNAIKYTDDDGFIEFTVKTTERQTILTVADNGPGISDADKAKIFDRFYRVDKARTRQKGG
FGLGLSLAKQIVDALKGDIQVKDNHPKGTIFEVRFNRHNFGK

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=409454 GPZ88_RS09190 WP_039696862.1 1811820..1813148(-) (ciaH) [Streptococcus ruminicola strain CNU_G2]
ATGCTGAATAACATACACAAAAAATTATCAACAGGAACGTTTTCTAATTTTTTCCATTTCTTCATTGTATTTACAGGAAT
TTTCATCATTATGACCACGATTATCTTGCAGATTATGCGTTATGGTCTATATTCTTCTGTAGATACCACTTTAAAAAATG
CAGCTGACAACGCAAGTGATTACGTCACACGAACAATGGAGCGTAGTGATTCCTTACAATCTAATAATAGTTTTAGTAAT
TCTGGAAAAGGAAAACCCAGCTCAAATGTGGCAAGTTTAAGTAATGTCAGTGTGCTATTGTACGATACAAATGGAAAAAT
CGTAAATGCAATTGATGCGTTTGTCCAGTTTGGGACATTAGCATCTAGTGTTGATGAAGACACTATTGGTGAGATTAAAG
ACGAGAAAATGACAACTATCTTTGGTCAAACCGAAAAATACCATGTTTTAACGGTTAGAGTGTATAGTAGTGACTATCCA
ACGATTGAATACGCGACTTTCTTAATCAGTGTTAGTCAGCTTGATGAGGCAAACGAACGTTATGTAACCATAACTGTTTC
AGTCATGATTATTTTCTGGATGATTTCAATTTTAGCAAGTATTTACTTGGCAAATTGGATGCGTAAACCAATTTTAGAAA
GTTATGAAAAACAAAAGCGTTTTGTTGAAAATGCTAGTCACGAATTAAGAACGCCGTTAGCGGTGCTTCAAAACCGACTT
GAAAGTCTTTTTAGACGACCGAATGCAACAATTCTTGATAACAGTGAAAGTATTGCAGCGAGTCTTGACGAAGTTCGTAA
TATGCGTATTTTAACAACCAATCTTTTGAACCTTGCTAGGCGAGATGATGGATTGAAAGTTGAATTAGAAGAAATCCAAC
CTTCAATCTTTAATGAAATTTTTGAGAATTACAACATGATTGCCGAAGAAAATGGTAAAACTTTTGTTGCTCATAATTCT
GCGGATCGTCCGATAAAAACTGATCGCACCTTGCTTAAACAATTGATGACAATCTTGTTTGATAATGCGATTAAGTACAC
TGATGACGACGGTTTTATTGAATTTACAGTTAAAACAACAGAACGCCAGACTATTCTAACCGTCGCTGATAATGGGCCAG
GTATTAGTGACGCTGATAAAGCGAAAATTTTTGATCGCTTTTATCGCGTTGATAAGGCAAGGACACGTCAAAAAGGTGGC
TTTGGACTTGGTCTATCCTTAGCTAAACAAATTGTTGATGCCTTAAAAGGTGATATTCAAGTTAAGGATAATCATCCAAA
AGGAACTATCTTTGAAGTTCGTTTTAACCGACATAATTTTGGTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A091BVP1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.54

98.416

0.586
  ciaH Streptococcus pneumoniae Rx1

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae D39

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae R6

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae TIGR4

52.174

98.869

0.516

Multiple sequence alignment