Detailed information NTG0409188

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: SAURSH1000_RS03625
• Genome accession: NZ_CP059180
• Coordinates: 756917..757999 (+)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain SH1000
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 751917..762999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAURSH1000_RS03605 (SAURSH1000_000720)	-	752772..753842 (-)	1071	WP_000460983.1	GGDEF domain-containing protein	-
SAURSH1000_RS03610 (SAURSH1000_000721)	-	754160..755215 (+)	1056	WP_000258151.1	MraY family glycosyltransferase	-
SAURSH1000_RS03615 (SAURSH1000_000722)	-	755385..756026 (-)	642	WP_000192947.1	YigZ family protein	-
SAURSH1000_RS03620 (SAURSH1000_000723)	fakB1	756170..756553 (+)	384	WP_001804582.1	fatty acid kinase FakB1	-
SAURSH1000_RS03625 (SAURSH1000_000724)	comFA	756917..757999 (+)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
SAURSH1000_RS03630 (SAURSH1000_000725)	-	757992..758666 (+)	675	WP_001057965.1	ComF family protein	-
SAURSH1000_RS03635 (SAURSH1000_000726)	raiA	758727..759299 (+)	573	WP_000617735.1	ribosome-associated translation inhibitor RaiA	-
SAURSH1000_RS03640 (SAURSH1000_000727)	secA	759713..762244 (+)	2532	WP_000506534.1	preprotein translocase subunit SecA	-
SAURSH1000_RS03645 (SAURSH1000_000728)	-	762286..762390 (+)	105	WP_001790092.1	hypothetical protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=409188 SAURSH1000_RS03625 WP_001548033.1 756917..757999(+) (comFA) [Staphylococcus aureus strain SH1000]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=409188 SAURSH1000_RS03625 WP_001548033.1 756917..757999(+) (comFA) [Staphylococcus aureus strain SH1000]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367