Detailed information NTG0409137

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GP482_RS07480
• Genome accession: NZ_CP046875
• Coordinates: 1534180..1536621 (-)
• Length: 813 a.a.
• NCBI ID: WP_158914592.1
• Uniprot ID: A0AAE6UZ66
• Organism: Streptococcus ruminicola strain CNU_77-61
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1529180..1541621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GP482_RS07460 (GP482_07460)	-	1530022..1530840 (+)	819	WP_158914590.1	hypothetical protein	-
GP482_RS07465 (GP482_07465)	-	1530867..1532138 (+)	1272	WP_074964931.1	toxic anion resistance protein	-
GP482_RS07470 (GP482_07470)	hslO	1532258..1533124 (+)	867	WP_006531039.1	Hsp33 family molecular chaperone HslO	-
GP482_RS07475 (GP482_07475)	dusB	1533117..1534094 (+)	978	WP_074603053.1	tRNA dihydrouridine synthase DusB	-
GP482_RS07480 (GP482_07480)	clpC	1534180..1536621 (-)	2442	WP_158914592.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GP482_RS07485 (GP482_07485)	-	1536618..1537079 (-)	462	WP_039696152.1	CtsR family transcriptional regulator	-
GP482_RS07490 (GP482_07490)	-	1537337..1537801 (+)	465	WP_074560991.1	small multi-drug export protein	-
GP482_RS07495 (GP482_07495)	tsf	1537901..1538938 (-)	1038	WP_074869514.1	translation elongation factor Ts	-
GP482_RS07500 (GP482_07500)	rpsB	1539047..1539814 (-)	768	WP_074564586.1	30S ribosomal protein S2	-
GP482_RS07510 (GP482_07510)	-	1540335..1541288 (+)	954	WP_158914594.1	S66 peptidase family protein	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90063.65 Da
• Isoelectric Point: 6.5806

>NTDB_id=409137 GP482_RS07480 WP_158914592.1 1534180..1536621(-) (clpC) [Streptococcus ruminicola strain CNU_77-61]
MSEYSMKMQEVFSIAQYQAARFESPYLESWHMLLAMVAVHDSVAGLTFAEYQNKIAYEEYEAAAVLALGKSPLADVKNVQ
FLEQSKALKDVLTFAESICKVTGSTEVGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDSARLLDLRKSLSRNAGFTKE
KIKAIHDLRKPKKATMGGAFSEMMKPQSTAGELSDFTRDLTELARQGKLEPVIGREKEVSRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGEIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEADGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHIEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYETFHNVTISDQ
AVLTAVKAAHRYLTSKNLPDSAIDLLDEASATVQGLVKKEAPAALTAADKAILEGDFKLATKLLKESRKKVTRKPTAVTE
DDIMATLSRLSGIPVEKMTQADSKKYLTLEKELHKRVIGQDAAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGARDMAHDYDAMQKRIMEELKKAYRPEFINRIDEKVVFHH
LTQENMRDVVKIMVKPLIETLAEKDITLKFQPSALKYLAEAGYDPEMGARPLRRTLQDKVEDKLSELILAGNLASGNTLK
IGVSKGQLKFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=409137 GP482_RS07480 WP_158914592.1 1534180..1536621(-) (clpC) [Streptococcus ruminicola strain CNU_77-61]
ATGAGTGAATATTCAATGAAAATGCAGGAGGTTTTCAGTATTGCCCAGTACCAAGCGGCGCGATTTGAAAGCCCATATTT
AGAAAGTTGGCATATGCTTTTAGCCATGGTAGCTGTTCATGATTCAGTGGCAGGGTTAACATTTGCTGAATACCAAAATA
AGATTGCTTACGAAGAGTACGAAGCGGCAGCTGTTTTGGCGCTCGGGAAATCACCTTTGGCAGATGTGAAAAATGTGCAG
TTCTTAGAACAATCTAAAGCCCTAAAAGACGTCTTAACTTTTGCTGAGTCAATTTGCAAAGTGACTGGCAGCACCGAAGT
CGGAACAGAGCATGTCCTTTATGCTATGTTGTTGAATCTTGATTTGTTTGCGACACGTTTGTTAGAAGTTGCTGGATTCA
AAAATAAGGAAGATGGTGATTCAGCACGCTTGCTTGATTTGCGTAAATCATTGTCACGTAATGCTGGATTTACTAAAGAA
AAAATCAAAGCTATTCACGATCTTCGCAAACCCAAAAAAGCTACAATGGGCGGAGCTTTCTCAGAAATGATGAAACCTCA
GTCAACTGCGGGAGAATTATCAGACTTCACTCGTGATTTAACTGAATTAGCTCGTCAAGGAAAACTTGAGCCAGTTATCG
GACGTGAAAAAGAAGTCTCTCGCATGGTTCAAGTACTTAGCCGTAAGACTAAAAATAATCCTGTCTTGGTCGGTGAAGCT
GGTGTCGGAAAAACGGCTCTTGCTTATGGTTTGGCACAACGTATTGTCAATGGTGAAATTCCTTATGAACTCCAAGATAT
GCGTGTCTTAGAGCTTGATATGATGAGTGTTGTTGCGGGGACTCGTTTCCGTGGTGATTTCGAAGAACGCATGAACCAAA
TCATCTCAGACATTGAAGCTGATGGTCATATTATTTTATTTATCGATGAAGTCCACACTATCATGGGTTCTGGTTCAGGT
ATTGATAGTACTTTGGATGCTGCTAATATCTTAAAACCTGCTCTTGCACGTGGTACGCTTCACATGGTTGGTGCGACAAC
TCAAGAAGAATATCAAAAACATATCGAAAAAGATGCAGCTCTTTCACGTCGTTTTGCGAAAATTACGATTGAAGAACCAA
GTGTTGAAGATGCTTATCAAATTTTACTTGGGCTTAAGAAATCTTACGAAACTTTCCATAATGTGACGATTTCTGATCAA
GCTGTGTTGACGGCTGTTAAAGCTGCACACCGTTATTTGACAAGTAAAAATCTACCAGATTCAGCTATTGATTTGCTTGA
TGAAGCTAGTGCAACTGTTCAAGGTTTGGTTAAAAAAGAAGCCCCAGCAGCTCTTACAGCTGCAGATAAAGCTATTTTAG
AAGGTGATTTCAAATTAGCTACAAAATTGCTTAAAGAGTCACGTAAGAAAGTGACACGTAAACCAACAGCTGTGACTGAA
GATGATATCATGGCAACACTTAGTCGTCTGTCAGGTATTCCTGTTGAGAAAATGACACAAGCCGATAGCAAGAAATATTT
GACGCTTGAAAAAGAACTTCACAAACGTGTTATCGGTCAAGATGCTGCGATTTCTGCTATCAGCCGTGCGATTCGCCGTA
ATCAAGCAGGTATTCGCACAGGTAAACGTCCAATTGGTTCATTCATGTTCTTAGGACCAACGGGTGTTGGTAAGACAGAA
TTGGCTAAAGCTTTGGCTGAACTTCTCTTTGATGATGAATCAGCACTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCGGCGAGTCGTTTGAACGGAGCTCCTCCAGGATACGTTGGTTATGAAGAAGGTGGCGAATTGACTGAAAAAGTTC
GTAACAAACCTTATTCAGTCCTTCTTTTCGATGAAGTTGAAAAAGCTCATCCAGATATTTTCAACGTCCTTCTTCAAGTT
TTGGATGATGGTGTGTTGACAGATAGTCGTGGTCGTAAAGTTGACTTCTCAAATACTATTATTATCATGACGTCAAACCT
TGGTGCGACTGCCCTTCGTGATGATAAAACTGTTGGATTTGGTGCGCGTGATATGGCTCATGATTATGATGCTATGCAAA
AACGTATCATGGAAGAACTTAAGAAAGCTTATCGTCCAGAATTTATCAACCGTATTGATGAAAAGGTTGTCTTCCACCAC
TTGACACAAGAAAATATGCGTGACGTGGTTAAAATCATGGTTAAACCATTGATTGAAACCTTAGCTGAAAAAGATATTAC
GCTCAAATTCCAACCATCAGCACTTAAATATCTTGCTGAGGCTGGATATGACCCAGAAATGGGAGCTCGTCCACTTCGTC
GTACTCTCCAAGATAAAGTTGAAGATAAATTATCAGAGCTTATCCTAGCAGGCAACCTAGCAAGTGGAAATACCCTTAAA
ATTGGTGTTTCTAAAGGACAACTCAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-134)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA lid domain (AAA_lid_9) (374-454)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	77.34	99.877	0.772
clpC	Streptococcus thermophilus LMG 18311	73.988	100	0.742
clpC	Streptococcus thermophilus LMD-9	73.865	100	0.74
clpC	Streptococcus pneumoniae TIGR4	67.488	99.877	0.674
clpC	Streptococcus pneumoniae Rx1	67.488	99.877	0.674
clpC	Streptococcus pneumoniae D39	67.488	99.877	0.674
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.94	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	43.923	100	0.449