Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   GPW70_RS10060 Genome accession   NZ_CP046740
Coordinates   1099795..1101924 (+) Length   709 a.a.
NCBI ID   WP_032472636.1    Uniprot ID   -
Organism   Vibrio cholerae strain 3566-06     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1094795..1106924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW70_RS10030 - 1095144..1095719 (-) 576 WP_000999601.1 PilZ domain-containing protein -
  GPW70_RS10035 lolC 1095895..1097103 (+) 1209 WP_032472633.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  GPW70_RS10040 lolD 1097096..1097782 (+) 687 WP_001061290.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  GPW70_RS10045 lolE 1097783..1099027 (+) 1245 WP_000493013.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  GPW70_RS10055 - 1099142..1099672 (-) 531 WP_032472634.1 DUF2062 domain-containing protein -
  GPW70_RS10060 comEC 1099795..1101924 (+) 2130 WP_032472636.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GPW70_RS10065 msbA 1101955..1103703 (+) 1749 WP_000052155.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  GPW70_RS10070 lpxK 1103706..1104713 (+) 1008 WP_025987731.1 tetraacyldisaccharide 4'-kinase -
  GPW70_RS10075 - 1104694..1104873 (+) 180 WP_000350068.1 Trm112 family protein -
  GPW70_RS10080 kdsB 1104873..1105631 (+) 759 WP_000011327.1 3-deoxy-manno-octulosonate cytidylyltransferase -

Sequence

Protein


Download         Length: 709 a.a.        Molecular weight: 79812.05 Da        Isoelectric Point: 7.5763

>NTDB_id=406918 GPW70_RS10060 WP_032472636.1 1099795..1101924(+) (comEC) [Vibrio cholerae strain 3566-06]
MVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNLLYQAGPDIIIKGRVDSFFTQTRYAYEGLVLIHEVNGQTLNKMTR
PRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYMAQSVVARAVVKPDTAYQIVQESGIRSSLFFELEQLTHT
SPYQGLILALTFGERKGIDEPEWQALRNSGLIHLVAISGLHIGIAFSVGYFLGLGMMRLHAQLLWSPFVCGALLAVLYAW
LAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLGAVLLWSPFASLSNSFWMSFLAVAIVLYQLASQSQSQVWWKA
LLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVIVPALFLGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQF
ADVGWWVVPSKVQGVVAASVAILLHYRFMSLKACSLLLGMMGLWWWFPSLTPLWRMDVLDVGHGLAIVIEQDERAIVYDT
GSSWPGGSYVQSVIEPILQQRGLRQVDGVILSHLDNDHAGDWQGLAERWQPNWIRASQLGTEFMPCIRGESWQWQSLHFT
VLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEWLLARDGAQLQSEVMIVPHHGSKTSSTAEFIAQVNPKLA
IASVAKDNRWNLPNPQVVARYQAQQVEWLDTGQAGQISLFFYPDQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide


Download         Length: 2130 bp        

>NTDB_id=406918 GPW70_RS10060 WP_032472636.1 1099795..1101924(+) (comEC) [Vibrio cholerae strain 3566-06]
ATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCTTCGTGGCTGCCATACTAACCATTGTGCTACAGGG
CAACCTTATACGAGATCAATCCAATCTGCTCTATCAAGCAGGGCCGGATATTATCATAAAAGGCCGTGTTGACAGCTTTT
TTACGCAAACTCGTTACGCTTATGAGGGTTTGGTCCTCATTCATGAAGTGAATGGACAAACCTTAAACAAAATGACTCGC
CCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGACCGCGTCGAATTTTCGGTAACTCTCAAGCCGATAGT
GGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATGGCGCAATCTGTCGTCGCACGGGCGGTCGTAAAAC
CTGACACCGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAGTTTGTTTTTTGAGCTGGAACAATTAACGCATACC
AGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAAAAGGTATTGATGAGCCAGAGTGGCAAGCCTTACG
CAATAGTGGCTTAATTCATTTAGTGGCGATTTCGGGGCTACACATTGGTATCGCTTTTAGCGTGGGTTATTTTCTCGGGC
TCGGCATGATGCGTCTTCATGCTCAGTTATTGTGGTCCCCTTTTGTGTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGG
CTGGCCGGATTTACTCTGCCCACTCAGCGCGCATTGATCATGTGCTTACTCAATGTGGCGTTGATCATGTTGGCTTTTCC
TCTTTCCGCGCTCAAGCGGATTCTACTCACCTTGGGCGCGGTCTTGCTTTGGTCGCCATTCGCCTCACTTTCAAACAGTT
TCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGCCAGTCAAAGCCAGAGTCAGGTGTGGTGGAAAGCT
CTGCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCACCGGTCACGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGC
AGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATTGTCCCAGCTTTGTTTTTGGGCCTACTACTCATGG
TGGTATGGCCTAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTGGACGTTTTTACCGCTCGATTGGGCTTTGCAGTTT
GCCGATGTAGGCTGGTGGGTGGTCCCCAGCAAAGTACAAGGTGTAGTCGCAGCGAGTGTGGCCATCCTCTTGCATTATCG
ATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATGGGCTTATGGTGGTGGTTTCCCTCTCTCACTCCACTTT
GGCGAATGGATGTGCTGGATGTTGGACATGGCTTGGCGATTGTGATTGAGCAAGATGAGCGAGCAATTGTCTACGATACA
GGCAGCAGTTGGCCGGGAGGCAGCTATGTGCAAAGCGTGATTGAGCCTATTCTCCAACAGCGAGGGCTACGCCAAGTCGA
TGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGGCAAGGTTTAGCTGAGCGCTGGCAACCTAATTGGA
TTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATCCGTGGTGAAAGCTGGCAGTGGCAATCTCTCCATTTTACG
GTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATTCGTGTGTGATTCGTATGACTGATACTCAGTCTAA
CCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGGAGTGGCTGCTTGCTCGAGACGGAGCGCAACTGCAAAGTG
AGGTGATGATCGTGCCGCACCACGGCAGTAAAACGTCGTCCACCGCAGAGTTTATTGCCCAAGTGAATCCCAAACTTGCG
ATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGCAAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGA
GTGGCTAGATACTGGACAAGCTGGGCAAATTAGCCTCTTTTTCTATCCAGATCAGCTGGATTGGTTTACCCAGCGTAGCC
TTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(12-135)

Metallo-beta-lactamase superfamily (Lactamase_B)

(461-641)

Competence protein (Competence)

(170-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

98.449

100

0.984
  comEC Vibrio parahaemolyticus RIMD 2210633

41.433

100

0.416
  comEC Vibrio campbellii strain DS40M4

41.018

99.718

0.409

Multiple sequence alignment