Detailed information    

insolico Bioinformatically predicted

Overview

Name   tfoX   Type   Regulator
Locus tag   GPW74_RS01570 Genome accession   NZ_CP046737
Coordinates   344672..345259 (+) Length   195 a.a.
NCBI ID   WP_001005366.1    Uniprot ID   A0A0K9UTP3
Organism   Vibrio cholerae strain 2015V-1126     
Function   master regulator of natural competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 339672..350259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW74_RS01550 panP 339994..341640 (-) 1647 WP_085602429.1 pyridoxal-dependent aspartate 1-decarboxylase PanP -
  GPW74_RS01555 - 341750..342259 (-) 510 WP_000826868.1 hypothetical protein -
  GPW74_RS01560 - 342448..343353 (-) 906 WP_123012223.1 lysine exporter LysO family protein -
  GPW74_RS01565 - 343374..344294 (-) 921 WP_184478465.1 HDOD domain-containing protein -
  GPW74_RS01570 tfoX 344672..345259 (+) 588 WP_001005366.1 TfoX/Sxy family DNA transformation protein Regulator
  GPW74_RS01575 - 345355..345903 (-) 549 WP_001232640.1 hypothetical protein -
  GPW74_RS01580 - 346094..346591 (-) 498 WP_001031962.1 response regulator -
  GPW74_RS01585 - 346588..348543 (-) 1956 WP_123012225.1 ATP-binding protein -
  GPW74_RS01590 - 348766..350031 (+) 1266 WP_025998897.1 YdgA family protein -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22816.03 Da        Isoelectric Point: 6.9718

>NTDB_id=406850 GPW74_RS01570 WP_001005366.1 344672..345259(+) (tfoX) [Vibrio cholerae strain 2015V-1126]
MNEQQFFDYVTKFGAYQKRSMFGGIGLFQHDAMYVLVSEDRIFVRGGEELDPELLALGCEKYRHVKKQTTATVNYYDITE
LYEQHHPELDSIIERSIQFSVNQREFQRSAASRRLRDLPNMQLTLERMVKKAGIDDVETFMSLGAPEVFNKVRQAYGSDV
DVKLLWKFAGAIEGIHWKLLQEPRKRQLLESCQQR

Nucleotide


Download         Length: 588 bp        

>NTDB_id=406850 GPW74_RS01570 WP_001005366.1 344672..345259(+) (tfoX) [Vibrio cholerae strain 2015V-1126]
ATGAATGAGCAACAGTTTTTCGACTACGTAACTAAGTTTGGCGCCTACCAAAAACGCTCGATGTTTGGTGGTATTGGCTT
GTTTCAACACGACGCTATGTATGTGTTGGTCAGTGAAGACCGCATTTTTGTGCGTGGTGGAGAAGAGCTCGACCCTGAGC
TCTTGGCCTTAGGGTGCGAGAAATATCGCCATGTTAAAAAACAGACAACGGCAACCGTAAACTATTACGACATCACTGAA
CTGTATGAGCAACATCACCCTGAGCTAGACTCGATCATTGAACGCTCGATTCAGTTTTCTGTGAATCAGCGGGAATTTCA
ACGCTCAGCAGCCAGTCGTCGTCTACGGGATTTACCCAATATGCAACTGACTTTGGAGCGTATGGTAAAAAAAGCGGGCA
TTGACGATGTGGAAACTTTTATGAGTCTCGGTGCGCCAGAAGTGTTTAATAAGGTGCGTCAAGCTTATGGAAGTGATGTC
GATGTAAAACTACTGTGGAAGTTTGCGGGTGCGATTGAAGGCATTCACTGGAAATTGCTGCAAGAGCCGCGTAAGCGCCA
ACTGTTAGAAAGTTGTCAGCAGCGTTAA

Domains

Predicted by InterproScan.

TfoX C-terminal domain (TfoX_C)

(112-190)

TfoX N-terminal domain (TfoX_N)

(9-99)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9UTP3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  tfoX Vibrio cholerae O1 biovar El Tor str. N16961

100

100

1
  tfoX Vibrio cholerae O1 biovar El Tor strain DRC-193A

100

100

1
  tfoX Vibrio cholerae O1 biovar El Tor strain P27459

100

100

1
  tfoX Vibrio cholerae O1 biovar El Tor strain E7946

100

100

1
  tfoX Vibrio cholerae strain A1552

100

100

1
  tfoX Vibrio campbellii strain DS40M4

69.43

98.974

0.687
  tfoX Vibrio parahaemolyticus RIMD 2210633

68.394

98.974

0.677
  tfoX Aliivibrio fischeri ES114

59.043

96.41

0.569

Multiple sequence alignment