Detailed information NTG0406282

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GPA00_RS02470
• Genome accession: NZ_CP046629
• Coordinates: 496846..499287 (-)
• Length: 813 a.a.
• NCBI ID: WP_157327413.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU G6
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 491846..504287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS02450 (GPA00_02450)	-	492711..493529 (+)	819	WP_157327407.1	hypothetical protein	-
GPA00_RS02455 (GPA00_02455)	-	493548..494822 (+)	1275	WP_157327409.1	toxic anion resistance protein	-
GPA00_RS02460 (GPA00_02460)	hslO	494936..495802 (+)	867	WP_074450857.1	Hsp33 family molecular chaperone HslO	-
GPA00_RS02465 (GPA00_02465)	dusB	495795..496772 (+)	978	WP_157327411.1	tRNA dihydrouridine synthase DusB	-
GPA00_RS02470 (GPA00_02470)	clpC	496846..499287 (-)	2442	WP_157327413.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GPA00_RS02475 (GPA00_02475)	-	499284..499745 (-)	462	WP_157327415.1	CtsR family transcriptional regulator	-
GPA00_RS02480 (GPA00_02480)	-	500005..500469 (+)	465	WP_021143271.1	COG2426 family protein	-
GPA00_RS02485 (GPA00_02485)	tsf	500855..501892 (-)	1038	WP_024344414.1	translation elongation factor Ts	-
GPA00_RS02490 (GPA00_02490)	rpsB	501999..502766 (-)	768	WP_021143273.1	30S ribosomal protein S2	-
GPA00_RS02500 (GPA00_02500)	-	503944..504096 (+)	153	WP_157327417.1	hypothetical protein	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90227.96 Da
• Isoelectric Point: 6.5810

>NTDB_id=406282 GPA00_RS02470 WP_157327413.1 496846..499287(-) (clpC) [Streptococcus equinus strain CNU G6]
MSEYSMKMQEVFSIAQFQAARFESPYLESWHVLLAMVAVHDSVAGLTFAEYQNKIAYEEYEAAAVLALGKSPLSDVKNVQ
FLEQSKALKDVLAFAESICKVTDGTEIGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDSVRLLDLRKSLSRNAGFTKE
KIKAIHDLRKPKKATMGGAFSEMMKPQSTAGELSDFTRDLTELARQGKLEPVIGREKEVSRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGEIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEADGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHIEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYETFHNVIISDE
AVLTVVKAAHRYLTSKNLPDSAIDLLDETSATVQGLVKKKAPEALTDIDKAILEGDFKKATKLLKKSRKVVTRKPAVVTE
DDIMATLSRLSGIPVEKMTQADSKKYLTLEKELHKRVIGQDAAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGARDMAHDYDAMQKRIMEELKKAYRPEFINRIDEKVVFHH
LTQENMRDVVKIMVKPLIATLAEKDITLKFQPSALKYLAEAGYDPEMGARPLRRTIQDKVEDKLSELILSGDLASGNTLK
IGVSKGQLKFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=406282 GPA00_RS02470 WP_157327413.1 496846..499287(-) (clpC) [Streptococcus equinus strain CNU G6]
ATGAGTGAATATTCAATGAAAATGCAGGAGGTTTTCAGCATTGCCCAGTTTCAGGCTGCGCGATTTGAAAGCCCATATTT
AGAAAGTTGGCATGTGCTTTTAGCCATGGTTGCTGTTCATGATTCAGTGGCTGGCTTGACGTTTGCTGAATATCAAAATA
AGATTGCCTATGAAGAGTATGAAGCAGCAGCTGTTTTGGCTCTTGGTAAATCACCATTGTCAGATGTGAAAAATGTTCAA
TTTTTAGAACAATCAAAGGCTTTAAAAGACGTGTTGGCGTTTGCTGAGTCTATTTGCAAAGTAACTGACGGTACAGAAAT
CGGAACTGAACACGTGCTTTATGCCATGCTCTTGAATCTTGATTTGTTTGCGACACGTTTGTTAGAAGTTGCTGGATTCA
AAAATAAAGAAGATGGTGACTCAGTTCGCTTGCTTGATTTACGCAAATCATTGTCACGTAATGCTGGATTTACCAAAGAA
AAAATCAAAGCTATCCATGATCTTCGTAAACCTAAAAAAGCTACAATGGGCGGAGCTTTCTCAGAAATGATGAAACCTCA
GTCAACTGCGGGAGAATTGTCAGATTTCACTCGTGATTTGACTGAATTAGCTCGTCAAGGAAAACTTGAGCCAGTTATCG
GACGTGAAAAAGAAGTCTCTCGCATGGTTCAAGTACTTAGCCGTAAGACTAAAAATAATCCTGTCTTAGTTGGTGAAGCT
GGTGTCGGAAAAACAGCTCTTGCTTATGGTTTGGCACAACGTATTGTCAATGGTGAAATTCCTTATGAACTCCAAGATAT
GCGTGTCTTAGAGCTTGATATGATGAGTGTTGTTGCGGGGACTCGTTTCCGTGGTGATTTCGAAGAACGCATGAACCAAA
TCATCTCAGACATTGAAGCGGATGGACATATCATTTTGTTCATCGATGAAGTCCACACTATCATGGGTTCTGGTTCAGGT
ATTGATAGTACTTTGGATGCTGCTAATATCTTAAAACCAGCTCTTGCACGTGGTACACTTCACATGGTTGGTGCGACAAC
ACAAGAAGAATACCAAAAACACATTGAAAAAGATGCTGCGCTTTCTCGTCGTTTTGCTAAAATTACGATTGAAGAGCCAA
GTGTTGAAGATGCTTATCAGATTCTTCTTGGACTTAAGAAATCTTATGAAACATTCCACAATGTTATCATTTCTGATGAA
GCTGTGCTGACTGTTGTTAAAGCTGCACACCGCTATTTGACAAGCAAAAATCTTCCAGACTCAGCTATTGATTTGCTTGA
TGAAACGAGTGCAACAGTCCAAGGTCTTGTTAAGAAAAAAGCTCCTGAAGCGTTGACTGATATTGATAAAGCTATCTTGG
AAGGTGATTTCAAAAAAGCAACGAAATTGCTTAAAAAATCTCGCAAGGTTGTGACACGTAAGCCAGCAGTTGTCACTGAG
GATGACATTATGGCAACTCTTAGCCGTCTGTCAGGTATTCCTGTTGAGAAAATGACACAAGCCGATAGCAAGAAATATTT
GACACTTGAAAAAGAACTTCACAAACGTGTTATCGGTCAAGATGCTGCGATTTCTGCTATCAGCCGTGCGATTCGCCGTA
ATCAAGCAGGTATTCGCACAGGTAAACGTCCAATTGGTTCTTTCATGTTCTTAGGACCAACTGGGGTTGGTAAGACAGAG
CTTGCTAAAGCTTTGGCAGAACTTCTTTTTGATGATGAATCTGCGCTTATTCGTTTCGACATGTCTGAGTACATGGAAAA
ATTCGCGGCGAGTCGTCTTAACGGAGCGCCTCCAGGATATGTTGGCTATGAAGAAGGTGGAGAACTTACAGAAAAAGTTC
GTAACAAACCTTATTCAGTTCTTCTATTTGATGAGGTTGAAAAAGCTCACCCAGACATTTTCAATGTGCTTCTTCAAGTC
TTGGATGATGGTGTGTTGACAGACAGTCGTGGTCGTAAAGTTGACTTCTCAAACACTATTATTATCATGACGTCAAACCT
TGGTGCGACAGCTCTTCGTGATGATAAGACTGTTGGATTTGGTGCGCGTGATATGGCCCATGACTATGATGCTATGCAAA
AACGTATCATGGAAGAACTTAAGAAAGCTTATCGTCCTGAGTTTATCAATCGTATTGATGAAAAAGTTGTCTTCCACCAT
TTAACTCAAGAAAATATGCGCGATGTTGTTAAAATTATGGTTAAACCATTGATTGCAACTTTGGCTGAAAAAGATATCAC
ACTTAAATTCCAACCATCAGCGCTTAAATACCTTGCTGAAGCTGGATATGACCCAGAAATGGGTGCTCGTCCACTTCGTC
GTACTATTCAAGATAAAGTCGAAGATAAACTATCTGAACTTATCCTATCAGGTGATTTGGCAAGCGGAAATACTCTTAAA
ATTGGTGTTTCAAAAGGTCAACTCAAATTTGATATTGCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-47)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-134)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA lid domain (AAA_lid_9) (374-459)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	77.956	99.877	0.779
clpC	Streptococcus thermophilus LMG 18311	73.742	100	0.739
clpC	Streptococcus thermophilus LMD-9	73.62	100	0.738
clpC	Streptococcus pneumoniae TIGR4	67.98	99.877	0.679
clpC	Streptococcus pneumoniae Rx1	67.98	99.877	0.679
clpC	Streptococcus pneumoniae D39	67.98	99.877	0.679
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.095	100	0.501
clpC	Bacillus subtilis subsp. subtilis str. 168	43.735	100	0.446