Detailed information    

insolico Bioinformatically predicted

Overview


Name   vicX   Type   Regulator
Locus tag   GPA00_RS00540 Genome accession   NZ_CP046629
Coordinates   110904..111713 (-) Length   269 a.a.
NCBI ID   WP_021142843.1    Uniprot ID   A0A1G9KLS3
Organism   Streptococcus equinus strain CNU G6     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 75954..127993 110904..111713 within 0


Gene organization within MGE regions


Location: 75954..127993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPA00_RS00340 (GPA00_00340) - 76178..76597 (-) 420 WP_021142824.1 DUF948 domain-containing protein -
  GPA00_RS00345 (GPA00_00345) lgt 76619..77401 (-) 783 WP_157327092.1 prolipoprotein diacylglyceryl transferase -
  GPA00_RS00350 (GPA00_00350) hprK 77394..78329 (-) 936 WP_021142826.1 HPr(Ser) kinase/phosphatase -
  GPA00_RS00355 (GPA00_00355) - 78641..78922 (-) 282 WP_021142827.1 PspC domain-containing protein -
  GPA00_RS00360 (GPA00_00360) - 79019..79456 (-) 438 WP_033153081.1 SprT family protein -
  GPA00_RS00365 (GPA00_00365) - 79443..81575 (-) 2133 WP_157327094.1 Tex family protein -
  GPA00_RS00370 (GPA00_00370) - 81762..81896 (+) 135 WP_094140269.1 SPJ_0845 family protein -
  GPA00_RS00375 (GPA00_00375) - 81902..82807 (+) 906 WP_024343740.1 permease -
  GPA00_RS00380 (GPA00_00380) - 82804..83616 (+) 813 WP_021142833.1 TIGR03943 family putative permease subunit -
  GPA00_RS00385 (GPA00_00385) - 83654..83821 (-) 168 WP_021142834.1 hypothetical protein -
  GPA00_RS00390 (GPA00_00390) ftsY 83827..85149 (-) 1323 WP_157327096.1 signal recognition particle-docking protein FtsY -
  GPA00_RS00395 (GPA00_00395) - 85190..86011 (-) 822 WP_021142837.1 Cof-type HAD-IIB family hydrolase -
  GPA00_RS00400 (GPA00_00400) - 86011..86808 (-) 798 WP_033153097.1 Cof-type HAD-IIB family hydrolase -
  GPA00_RS00405 (GPA00_00405) - 86984..87793 (+) 810 WP_157327098.1 DUF6287 domain-containing protein -
  GPA00_RS00410 (GPA00_00410) - 87858..88268 (-) 411 WP_074639435.1 NUDIX hydrolase -
  GPA00_RS00415 (GPA00_00415) smc 88284..91823 (-) 3540 WP_157327100.1 chromosome segregation protein SMC -
  GPA00_RS00420 (GPA00_00420) rnc 91970..92656 (-) 687 WP_021142842.1 ribonuclease III -
  GPA00_RS00425 (GPA00_00425) - 93006..94223 (-) 1218 WP_001291561.1 tyrosine-type recombinase/integrase -
  GPA00_RS00430 (GPA00_00430) - 94305..94508 (-) 204 WP_000814511.1 excisionase -
  GPA00_RS09800 (GPA00_00435) - 94492..94743 (+) 252 WP_001845478.1 hypothetical protein -
  GPA00_RS00440 (GPA00_00440) - 94969..95199 (-) 231 WP_000857133.1 helix-turn-helix domain-containing protein -
  GPA00_RS00445 (GPA00_00445) - 95196..95618 (-) 423 WP_000804885.1 sigma-70 family RNA polymerase sigma factor -
  GPA00_RS00455 (GPA00_00455) - 96123..96476 (+) 354 WP_001227347.1 helix-turn-helix transcriptional regulator -
  GPA00_RS00460 (GPA00_00460) - 96536..96703 (-) 168 WP_000336323.1 cysteine-rich KTR domain-containing protein -
  GPA00_RS00465 (GPA00_00465) tet(M) 96822..98741 (-) 1920 WP_157327101.1 tetracycline resistance ribosomal protection protein Tet(M) -
  GPA00_RS09895 - 98757..98804 (-) 48 Protein_91 hypothetical protein -
  GPA00_RS00475 (GPA00_00475) - 99118..100050 (-) 933 WP_001224318.1 conjugal transfer protein -
  GPA00_RS00480 (GPA00_00480) - 100047..101048 (-) 1002 WP_000769868.1 lysozyme family protein -
  GPA00_RS00485 (GPA00_00485) - 101045..103222 (-) 2178 WP_000804748.1 CD3337/EF1877 family mobilome membrane protein -
  GPA00_RS00490 (GPA00_00490) - 103225..105672 (-) 2448 WP_157327103.1 ATP-binding protein -
  GPA00_RS00495 (GPA00_00495) - 105656..106048 (-) 393 WP_000723888.1 conjugal transfer protein -
  GPA00_RS00500 (GPA00_00500) - 106137..106634 (-) 498 WP_000342539.1 antirestriction protein ArdA -
  GPA00_RS00505 (GPA00_00505) - 106751..106972 (-) 222 WP_001009056.1 hypothetical protein -
  GPA00_RS00510 (GPA00_00510) mobT 107015..108220 (-) 1206 WP_000398284.1 MobT family relaxase -
  GPA00_RS00515 (GPA00_00515) - 108243..108395 (-) 153 WP_000879507.1 hypothetical protein -
  GPA00_RS00520 (GPA00_00520) - 108398..109783 (-) 1386 WP_000813488.1 FtsK/SpoIIIE domain-containing protein -
  GPA00_RS00525 (GPA00_00525) - 109812..110198 (-) 387 WP_000985015.1 YdcP family protein -
  GPA00_RS00530 (GPA00_00530) - 110214..110528 (-) 315 WP_000420682.1 YdcP family protein -
  GPA00_RS00540 (GPA00_00540) vicX 110904..111713 (-) 810 WP_021142843.1 MBL fold metallo-hydrolase Regulator
  GPA00_RS00545 (GPA00_00545) vicK 111714..113066 (-) 1353 WP_024343735.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPA00_RS00550 (GPA00_00550) vicR 113059..113769 (-) 711 WP_021142846.1 response regulator YycF Regulator
  GPA00_RS00555 (GPA00_00555) - 114077..114841 (+) 765 WP_024343734.1 amino acid ABC transporter ATP-binding protein -
  GPA00_RS00560 (GPA00_00560) - 114846..115655 (+) 810 WP_157327105.1 transporter substrate-binding domain-containing protein -
  GPA00_RS00565 (GPA00_00565) - 115671..116375 (+) 705 WP_039698014.1 amino acid ABC transporter permease -
  GPA00_RS00570 (GPA00_00570) - 116385..117032 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  GPA00_RS00575 (GPA00_00575) - 117064..117672 (-) 609 WP_074450680.1 TVP38/TMEM64 family protein -
  GPA00_RS00580 (GPA00_00580) - 117890..118186 (-) 297 WP_045797684.1 hypothetical protein -
  GPA00_RS00585 (GPA00_00585) - 118370..119860 (-) 1491 WP_157328499.1 sensor histidine kinase -
  GPA00_RS00590 (GPA00_00590) - 119832..120524 (-) 693 WP_024343730.1 response regulator transcription factor -
  GPA00_RS00595 (GPA00_00595) - 120613..121494 (-) 882 WP_157327107.1 DUF3114 domain-containing protein -
  GPA00_RS00600 (GPA00_00600) - 121576..122094 (+) 519 WP_021142857.1 TetR/AcrR family transcriptional regulator -
  GPA00_RS00605 (GPA00_00605) - 122209..123978 (+) 1770 WP_157327109.1 oleate hydratase -
  GPA00_RS09805 - 124043..124879 (-) 837 WP_232524212.1 pectate lyase -
  GPA00_RS09810 - 124940..125941 (-) 1002 WP_232524214.1 hypothetical protein -

Sequence


Protein


Download         Length: 269 a.a.        Molecular weight: 30229.07 Da        Isoelectric Point: 5.1978

>NTDB_id=406266 GPA00_RS00540 WP_021142843.1 110904..111713(-) (vicX) [Streptococcus equinus strain CNU G6]
MSENAFKYSVLASGSTGNSFYVETPQKRLLIDAGLTGKKITSLLADIDRKPEDLDAILITHEHSDHIKGVGVLARRYNLD
VYANEKTWQMIDERNMIGKLDTAQKHVFERGKVLTFGDIDIESFGVSHDAVDPQFYRLMKDNKSFVVLTDTGYVSDRMAG
VIENADGYLIESNHDVEILRAGSYPWSLKQRILSDRGHLSNEDGADTMIRTIGNRTKKIYLGHLSKENNIKELAHMTMEN
NLMQADFAVGHDMTVFDTSPDEATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=406266 GPA00_RS00540 WP_021142843.1 110904..111713(-) (vicX) [Streptococcus equinus strain CNU G6]
ATGTCTGAGAATGCTTTTAAATATAGTGTCTTAGCTTCCGGTTCTACTGGTAACTCATTTTATGTGGAAACACCACAAAA
ACGTCTTTTGATTGATGCAGGGTTGACTGGTAAGAAAATTACCAGTCTTCTTGCTGATATTGATCGAAAACCAGAAGATT
TGGATGCTATTTTAATTACACACGAACATTCCGACCATATTAAGGGTGTTGGAGTGCTTGCTCGTCGTTACAATCTTGAT
GTTTATGCCAATGAAAAAACTTGGCAAATGATTGATGAGCGCAATATGATTGGAAAACTTGACACTGCTCAGAAACATGT
TTTTGAGCGTGGTAAAGTATTGACTTTCGGTGATATTGATATTGAAAGTTTCGGAGTTAGCCACGATGCGGTTGATCCAC
AATTTTACCGTTTGATGAAAGATAACAAATCATTTGTTGTTTTGACTGATACGGGCTATGTTAGTGATAGAATGGCTGGC
GTCATTGAAAATGCAGATGGCTATTTGATTGAGTCAAATCACGATGTTGAGATATTGCGTGCGGGTTCTTATCCATGGAG
CTTAAAACAACGTATCTTATCTGATAGAGGGCATTTATCAAATGAAGATGGTGCAGATACGATGATTCGCACCATTGGTA
ATCGTACGAAAAAAATCTATCTTGGTCACTTGAGTAAGGAAAATAATATCAAAGAACTAGCTCACATGACTATGGAAAAT
AATTTGATGCAAGCTGATTTTGCGGTTGGACACGATATGACTGTCTTTGATACGTCACCGGATGAAGCAACGCCATTAAC
TGAAATCTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A1G9KLS3

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

76.208

100

0.762


Multiple sequence alignment