Detailed information NTG0406236

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GO596_RS03595
• Genome accession: NZ_CP046628
• Coordinates: 710511..712952 (+)
• Length: 813 a.a.
• NCBI ID: WP_021143269.1
• Uniprot ID: A0A1G9LNK6
• Organism: Streptococcus equinus strain CNU 77-23
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 705511..717952

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO596_RS03575 (GO596_03575)	rpsB	707032..707799 (+)	768	WP_021143273.1	30S ribosomal protein S2	-
GO596_RS03580 (GO596_03580)	tsf	707906..708943 (+)	1038	WP_021143272.1	translation elongation factor Ts	-
GO596_RS03585 (GO596_03585)	-	709329..709793 (-)	465	WP_021143271.1	COG2426 family protein	-
GO596_RS03590 (GO596_03590)	-	710053..710514 (+)	462	WP_004233448.1	CtsR family transcriptional regulator	-
GO596_RS03595 (GO596_03595)	clpC	710511..712952 (+)	2442	WP_021143269.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GO596_RS03600 (GO596_03600)	dusB	713036..714013 (-)	978	WP_027968310.1	tRNA dihydrouridine synthase DusB	-
GO596_RS03605 (GO596_03605)	hslO	714006..714872 (-)	867	WP_074450857.1	Hsp33 family molecular chaperone HslO	-
GO596_RS03610 (GO596_03610)	-	715174..716064 (+)	891	WP_039691283.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90199.91 Da
• Isoelectric Point: 6.5810

>NTDB_id=406236 GO596_RS03595 WP_021143269.1 710511..712952(+) (clpC) [Streptococcus equinus strain CNU 77-23]
MSEYSMKMQEVFSIAQFQAARFESPYLESWHVLLAMVAVHDSVAGLTFAEYQNKIAYEEYEAAAVLALGKSPLSDVKNVQ
FLEQSKALKDVLAFAESICKVTDGTEIGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDSVRLLDLRKSLSRNAGFTKE
KIKAIHDLRKPKKATMGGAFSEMMKPQSTAGELSDFTRDLTELARQGKLEPVIGREKEVSRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGEIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEADGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHIEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYETFHNVIISDE
AVLTAVKAAHRYLTSKNLPDSAIDLLDETSATVQGLVKKKAPEALTDIDKAILEGDFKKATKLLKKSRKVVTRKPAVVTE
DDIMATLSRLSGIPVEKMTQADSKKYLTLEKELHKRVIGQDAAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGARDMAHDYDAMQKRIMEELKKAYRPEFINRIDEKVVFHH
LTQENMRDVVKIMVKPLIATLAEKDITLKFQPSALKYLAEAGYDPEMGARPLRRTIQDKVEDKLSELILSGDLASGNTLK
IGVSKGQLKFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=406236 GO596_RS03595 WP_021143269.1 710511..712952(+) (clpC) [Streptococcus equinus strain CNU 77-23]
ATGAGTGAATATTCAATGAAAATGCAGGAGGTTTTCAGCATTGCCCAGTTTCAGGCTGCGCGATTTGAAAGCCCATATTT
AGAAAGTTGGCATGTGCTTTTAGCCATGGTTGCTGTTCATGATTCAGTGGCTGGCTTGACGTTTGCTGAATATCAAAATA
AGATTGCCTATGAAGAGTACGAAGCAGCAGCTGTTTTGGCCCTTGGTAAATCACCATTGTCAGATGTGAAAAATGTTCAA
TTTTTAGAACAATCAAAGGCTTTAAAAGACGTGTTGGCGTTTGCTGAGTCTATTTGCAAAGTAACTGACGGTACAGAAAT
CGGAACTGAGCACGTGCTTTATGCCATGCTCTTGAATCTTGATTTGTTTGCGACACGTTTGTTAGAAGTTGCTGGATTCA
AAAATAAAGAAGATGGTGACTCAGTTCGCTTGCTTGATTTACGCAAATCATTGTCACGTAATGCTGGATTTACCAAAGAA
AAAATCAAAGCTATCCATGATCTTCGTAAGCCTAAAAAAGCTACGATGGGCGGAGCTTTCTCAGAAATGATGAAACCTCA
GTCAACTGCGGGAGAATTATCAGACTTCACTCGTGATTTAACTGAATTAGCTCGTCAAGGAAAACTTGAGCCAGTTATTG
GACGTGAAAAAGAAGTCTCTCGCATGGTTCAAGTACTTAGCCGTAAGACTAAAAATAATCCTGTCTTAGTTGGTGAAGCT
GGTGTCGGAAAAACGGCTCTTGCTTATGGTTTGGCACAACGTATTGTCAATGGTGAAATTCCTTATGAACTCCAAGATAT
GCGTGTCTTAGAGCTTGATATGATGAGTGTTGTTGCGGGGACTCGTTTCCGTGGTGATTTCGAAGAACGCATGAACCAAA
TCATCTCAGACATTGAAGCTGATGGTCATATTATTTTGTTTATCGATGAAGTCCACACTATCATGGGTTCTGGTTCAGGT
ATTGATAGCACTTTGGATGCTGCTAATATCTTAAAACCAGCTCTTGCGCGTGGTACACTTCACATGGTTGGTGCGACAAC
ACAAGAAGAATACCAAAAACACATTGAAAAAGATGCTGCGCTTTCTCGTCGTTTTGCTAAAATTACGATTGAAGAGCCAA
GTGTTGAAGATGCTTATCAGATTCTTCTTGGACTTAAGAAATCTTATGAAACATTCCACAATGTTATCATTTCTGATGAA
GCTGTGCTGACTGCTGTTAAAGCTGCACACCGCTATTTGACAAGCAAAAATCTTCCAGACTCAGCTATTGATTTGCTTGA
TGAAACGAGTGCAACAGTTCAAGGTCTTGTTAAGAAAAAAGCTCCTGAAGCGTTGACTGATATTGATAAAGCTATCTTGG
AAGGTGATTTCAAAAAAGCAACGAAATTGCTTAAAAAATCTCGCAAGGTTGTGACACGTAAGCCAGCAGTTGTCACTGAA
GATGACATTATGGCAACTCTTAGCCGTCTGTCAGGTATTCCTGTTGAGAAAATGACACAAGCTGATAGCAAGAAATATTT
GACGCTTGAAAAAGAACTTCACAAACGTGTTATCGGTCAAGATGCTGCGATTTCTGCTATCAGCCGTGCGATTCGCCGTA
ATCAGGCAGGTATTCGCACAGGTAAACGTCCGATTGGTTCTTTCATGTTCTTAGGACCAACTGGGGTTGGTAAGACAGAG
CTTGCTAAAGCTTTGGCAGAACTTCTTTTTGATGATGAATCTGCGCTTATTCGTTTCGACATGTCTGAGTACATGGAAAA
ATTCGCGGCGAGTCGTCTTAACGGAGCGCCTCCAGGATATGTTGGCTATGAAGAAGGTGGAGAACTTACAGAAAAAGTTC
GTAACAAACCTTATTCAGTCCTTCTATTTGATGAGGTTGAAAAAGCTCACCCAGACATTTTCAATGTGCTTCTTCAAGTC
TTGGATGATGGTGTGTTGACAGACAGTCGTGGTCGTAAAGTTGACTTCTCAAACACTATTATTATCATGACGTCAAACCT
TGGTGCGACAGCTCTTCGTGATGATAAGACTGTTGGATTTGGTGCGCGTGATATGGCTCATGACTATGATGCTATGCAAA
AACGTATCATGGAAGAACTTAAGAAAGCTTATCGTCCTGAGTTTATCAACCGTATTGATGAAAAAGTTGTTTTCCACCAT
TTAACTCAAGAAAATATGCGCGATGTTGTTAAAATTATGGTTAAACCATTGATTGCAACTTTGGCTGAAAAAGATATCAC
ACTTAAATTCCAACCATCAGCGCTTAAATACCTTGCTGAAGCTGGATATGACCCAGAAATGGGTGCTCGTCCACTTCGCC
GTACTATTCAAGATAAAGTCGAAGATAAACTATCTGAACTTATCCTATCAGGTGATTTGGCAAGCGGAAATACTCTTAAA
ATTGGTGTTTCAAAAGGTCAACTCAAATTTGATATTGCATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-47)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-134)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA lid domain (AAA_lid_9) (374-459)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

3D structure

• AlphaFold DB: A0A1G9LNK6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	78.079	99.877	0.78
clpC	Streptococcus thermophilus LMG 18311	73.865	100	0.74
clpC	Streptococcus thermophilus LMD-9	73.742	100	0.739
clpC	Streptococcus pneumoniae TIGR4	68.103	99.877	0.68
clpC	Streptococcus pneumoniae Rx1	68.103	99.877	0.68
clpC	Streptococcus pneumoniae D39	68.103	99.877	0.68
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.216	100	0.502
clpC	Bacillus subtilis subsp. subtilis str. 168	43.855	100	0.448