Detailed information NTG0040623

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SSUJS14_RS09510
• Genome accession: NC_017618
• Coordinates: 1918806..1921259 (-)
• Length: 817 a.a.
• NCBI ID: WP_014636516.1
• Uniprot ID: -
• Organism: Streptococcus suis JS14
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1913806..1926259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUJS14_RS09485 (SSUJS14_1929)	hslO	1914049..1914915 (+)	867	WP_012027852.1	Hsp33 family molecular chaperone HslO	-
SSUJS14_RS09490 (SSUJS14_1930)	dusB	1914908..1915912 (+)	1005	WP_012775355.1	tRNA dihydrouridine synthase DusB	-
SSUJS14_RS09495 (SSUJS14_1931)	-	1916058..1916831 (-)	774	WP_012027854.1	NUDIX domain-containing protein	-
SSUJS14_RS09500 (SSUJS14_1932)	pnuC	1916824..1917645 (-)	822	WP_012027855.1	nicotinamide riboside transporter PnuC	-
SSUJS14_RS09505 (SSUJS14_1933)	-	1917655..1918692 (-)	1038	WP_012028524.1	AAA family ATPase	-
SSUJS14_RS09510 (SSUJS14_1934)	clpC	1918806..1921259 (-)	2454	WP_014636516.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SSUJS14_RS09515 (SSUJS14_1935)	-	1921265..1921723 (-)	459	WP_012027859.1	CtsR family transcriptional regulator	-
SSUJS14_RS09525 (SSUJS14_1936)	-	1921873..1922222 (+)	350	Protein_1819	thioredoxin domain-containing protein	-
SSUJS14_RS09530 (SSUJS14_1938)	-	1922222..1922923 (+)	702	WP_012027861.1	hypothetical protein	-
SSUJS14_RS09535 (SSUJS14_1939)	tsf	1923186..1924226 (-)	1041	WP_012027862.1	translation elongation factor Ts	-
SSUJS14_RS09540 (SSUJS14_1940)	rpsB	1924382..1925158 (-)	777	WP_012775356.1	30S ribosomal protein S2	-
SSUJS14_RS09545 (SSUJS14_1941)	-	1925505..1926017 (-)	513	WP_012775452.1	adenylate kinase	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90162.56 Da
• Isoelectric Point: 6.3138

>NTDB_id=40623 SSUJS14_RS09510 WP_014636516.1 1918806..1921259(-) (clpC) [Streptococcus suis JS14]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFATSRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG

Nucleotide

• Length: 2454 bp

>NTDB_id=40623 SSUJS14_RS09510 WP_014636516.1 1918806..1921259(-) (clpC) [Streptococcus suis JS14]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGACTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-54)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (104-130)

• ATPase family associated with various cellular activities (AAA) (AAA) (232-364)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• AAA lid domain (AAA_lid_9) (371-451)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-802)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	71.341	99.51	0.71
clpC	Streptococcus pneumoniae Rx1	71.341	99.51	0.71
clpC	Streptococcus pneumoniae D39	71.341	99.51	0.71
clpC	Streptococcus mutans UA159	66.049	99.143	0.655
clpC	Streptococcus thermophilus LMG 18311	64.706	99.878	0.646
clpC	Streptococcus thermophilus LMD-9	64.583	99.878	0.645
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.206	100	0.493
clpC	Bacillus subtilis subsp. subtilis str. 168	44.526	99.51	0.443