Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HZR12_RS04220 Genome accession   NZ_CP058615
Coordinates   848489..849205 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   P0A0I7
Organism   Staphylococcus aureus strain 110900     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 843489..854205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HZR12_RS04200 (HZR12_04200) - 844583..845533 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  HZR12_RS04205 (HZR12_04205) - 845682..847166 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  HZR12_RS04210 (HZR12_04210) - 847163..848122 (+) 960 WP_001253312.1 carbohydrate kinase -
  HZR12_RS04215 (HZR12_04215) - 848310..848417 (-) 108 WP_001790167.1 hypothetical protein -
  HZR12_RS04220 (HZR12_04220) agrA 848489..849205 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  HZR12_RS04225 (HZR12_04225) agrC 849224..850516 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  HZR12_RS04230 (HZR12_04230) agrD 850541..850681 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  HZR12_RS04235 (HZR12_04235) agrB 850678..851247 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  HZR12_RS14945 hld 851537..851617 (+) 81 WP_000046022.1 delta-hemolysin -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=405910 HZR12_RS04220 WP_000688492.1 848489..849205(-) (agrA) [Staphylococcus aureus strain 110900]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=405910 HZR12_RS04220 WP_000688492.1 848489..849205(-) (agrA) [Staphylococcus aureus strain 110900]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3BS1
  PDB 4G4K

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment