Detailed information NTG0405535

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GNK04_RS03515
• Genome accession: NZ_CP046564
• Coordinates: 643618..645750 (+)
• Length: 710 a.a.
• NCBI ID: WP_159781208.1
• Uniprot ID: A0A7Z2QAJ5
• Organism: Bacillus sp. N1-1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 638618..650750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GNK04_RS03480 (GNK04_03480)	-	639120..639560 (+)	441	WP_159781202.1	hypothetical protein	-
GNK04_RS03485 (GNK04_03485)	-	639739..640125 (+)	387	WP_159781203.1	general stress protein	-
GNK04_RS03490 (GNK04_03490)	-	640240..640437 (-)	198	WP_098446507.1	DUF2188 domain-containing protein	-
GNK04_RS03495 (GNK04_03495)	-	640821..641180 (-)	360	WP_159781204.1	DUF4870 domain-containing protein	-
GNK04_RS03500 (GNK04_03500)	-	641286..641630 (-)	345	WP_159781205.1	hypothetical protein	-
GNK04_RS03505 (GNK04_03505)	mnmH	641747..642808 (+)	1062	WP_159781206.1	tRNA 2-selenouridine(34) synthase MnmH	-
GNK04_RS03510 (GNK04_03510)	-	642771..643235 (-)	465	WP_159781207.1	hypothetical protein	-
GNK04_RS03515 (GNK04_03515)	clpC	643618..645750 (+)	2133	WP_159781208.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GNK04_RS03520 (GNK04_03520)	-	646011..647279 (+)	1269	WP_159781209.1	ATP-grasp domain-containing protein	-
GNK04_RS03525 (GNK04_03525)	-	647312..649282 (+)	1971	WP_159781210.1	hypothetical protein	-
GNK04_RS03530 (GNK04_03530)	-	649402..649698 (+)	297	WP_098446515.1	Dabb family protein	-
GNK04_RS03535 (GNK04_03535)	-	649721..650722 (+)	1002	WP_159781211.1	zinc-binding dehydrogenase	-

Sequence

Protein

• Length: 710 a.a.
• Molecular weight: 78885.35 Da
• Isoelectric Point: 4.9020

>NTDB_id=405535 GNK04_RS03515 WP_159781208.1 643618..645750(+) (clpC) [Bacillus sp. N1-1]
MLCDQCQQNQASVQLNVQMNQHKKRVNLCSTCYANVMNGQTASSPKGQMDDFFQSFMASAGQNGFTGQEDGPQTESGNGK
GGLLDNLGRNLSDAAKAGLIDPVIGRENEVARVIETLNRRNKNNPVLIGEAGVGKTAIAEGLALRISEGQVPSKLKNKEI
YLLDVASLVSNTGVRGQFEERMKQLISELQSRKNVILFIDELHQIVGAGSAEGSMDAGNILKPALARGELQLIGATTLKE
YRQIEKDAALERRFQPVMVNEPTVEEAIQILKGLQPKYEEYHEVNYTEEAIRACVSLSNRFIQDRFLPDKAIDLMDEAGA
KMNLTFAVSNHDEIQQRLHQIATEKNKAAEAEDYELAAKLRTEELQLEKQLEETLKSNSNMNHSVDLDEIQQIVEGKTGI
PVRKLREDEQTKMKNLAERLNAKVIGQEDAVNKVAKAIRRSRAGLKRQNRPIGSFLFVGPTGVGKTELSRSLAEEMFGDR
DAMIRLDMSEYMEKHSVSKLIGSPPGYVGHEEAGQLTERVRRKPYSIILIDEVEKAHPDVQNMFLQILDDGRLTDSQGRT
VSFKDTVIIMTSNAGTSERRITVGFESAESYTGVMESLGGYFRPEFLNRFDGIIPFKSLEQSSLVTIVDLMINDLDESLE
EQDITLTISEAAKEKLAELGYNPQFGARPLRRVIEEHVEDGIADLLVDEGSIKSVTVEIVEDKIVVSQKK

Nucleotide

• Length: 2133 bp

>NTDB_id=405535 GNK04_RS03515 WP_159781208.1 643618..645750(+) (clpC) [Bacillus sp. N1-1]
ATGCTTTGTGATCAATGCCAACAAAATCAGGCTTCGGTTCAACTGAATGTCCAAATGAATCAACATAAGAAAAGAGTTAA
CCTTTGTAGCACGTGTTACGCAAATGTGATGAATGGTCAAACAGCTTCATCACCAAAAGGTCAAATGGATGATTTCTTTC
AATCCTTTATGGCTTCAGCAGGACAAAATGGTTTTACGGGTCAAGAAGATGGACCACAAACAGAATCAGGGAATGGTAAA
GGCGGTTTACTTGATAACCTCGGACGAAATTTATCTGACGCAGCAAAAGCTGGTTTGATTGACCCAGTCATTGGGCGCGA
AAATGAGGTAGCGAGAGTGATTGAAACATTAAACCGTCGTAATAAAAATAATCCAGTTTTAATCGGTGAAGCAGGTGTCG
GAAAAACGGCGATTGCAGAAGGTCTTGCTTTGAGAATTTCAGAAGGTCAAGTACCTTCTAAACTAAAGAATAAAGAAATT
TATTTATTAGATGTTGCATCTCTTGTTTCAAATACGGGTGTAAGAGGTCAGTTTGAAGAAAGAATGAAGCAACTGATTTC
TGAACTTCAAAGTCGAAAAAATGTAATCTTATTTATAGATGAACTGCATCAAATTGTAGGGGCTGGATCTGCAGAAGGAT
CTATGGATGCAGGAAACATTTTAAAACCAGCTCTTGCAAGAGGCGAGCTTCAATTAATTGGGGCAACAACTCTTAAAGAA
TATCGTCAAATCGAAAAGGATGCAGCATTAGAACGACGTTTTCAACCAGTAATGGTGAATGAGCCTACTGTAGAAGAAGC
CATTCAGATTCTAAAAGGTTTGCAACCTAAGTATGAAGAGTACCATGAAGTGAACTATACGGAAGAAGCGATTCGTGCGT
GTGTCTCATTATCGAACCGGTTCATTCAAGATCGTTTCTTACCAGATAAAGCAATCGACTTAATGGATGAAGCAGGCGCC
AAAATGAACCTAACGTTTGCTGTGTCGAACCACGATGAAATTCAGCAGCGTTTACACCAGATTGCTACTGAAAAAAACAA
GGCAGCAGAGGCAGAAGATTATGAGCTAGCTGCAAAACTAAGAACAGAAGAATTACAGCTTGAGAAACAGCTCGAAGAAA
CGTTGAAAAGCAACTCAAATATGAATCATTCAGTGGATCTTGATGAGATTCAGCAGATTGTAGAGGGAAAAACAGGTATT
CCAGTCCGTAAGCTTCGGGAAGATGAGCAAACGAAAATGAAAAACCTTGCAGAGCGACTGAATGCTAAAGTAATTGGTCA
GGAAGATGCTGTTAACAAAGTAGCAAAAGCAATTCGCCGAAGTCGTGCAGGATTAAAACGCCAGAATCGTCCAATAGGTT
CTTTCCTATTCGTCGGTCCAACTGGTGTCGGAAAAACAGAACTTTCCCGTTCTCTTGCAGAAGAAATGTTCGGTGATCGA
GATGCGATGATTCGACTTGATATGAGTGAATATATGGAAAAACACTCTGTCTCTAAACTGATCGGTTCCCCTCCGGGCTA
TGTCGGTCATGAGGAAGCAGGCCAATTAACAGAAAGAGTACGTCGTAAACCATATAGCATCATCTTAATTGATGAAGTGG
AGAAAGCTCATCCTGATGTACAAAATATGTTCCTTCAAATCCTTGATGATGGGCGTCTTACAGATAGTCAAGGTAGGACG
GTAAGCTTTAAAGATACGGTTATTATCATGACAAGTAATGCCGGAACTTCTGAGCGAAGAATTACTGTTGGTTTTGAATC
AGCAGAAAGCTATACAGGCGTGATGGAGAGTCTTGGTGGTTACTTTAGACCTGAATTCTTAAATCGATTTGATGGAATTA
TTCCATTTAAGTCACTTGAACAATCAAGTCTCGTTACCATTGTAGACCTTATGATTAATGATTTAGATGAAAGCCTTGAA
GAACAAGATATTACACTTACAATTAGTGAAGCAGCAAAAGAGAAGTTGGCTGAACTTGGATATAATCCACAGTTTGGTGC
ACGCCCTCTTCGCAGAGTGATTGAAGAACATGTGGAAGATGGTATTGCTGATTTGCTTGTCGATGAAGGCAGTATCAAAT
CCGTGACGGTTGAAATTGTAGAAGATAAGATTGTTGTTTCACAAAAGAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (263-362)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (619-693)

• AAA domain (Cdc48 subfamily) (AAA_2) (450-611)

• ATPase family associated with various cellular activities (AAA) (AAA) (126-257)

3D structure

• AlphaFold DB: A0A7Z2QAJ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	56.581	100	0.587
clpE	Streptococcus mutans UA159	56.925	100	0.579
clpE	Streptococcus pneumoniae Rx1	54.496	100	0.563
clpE	Streptococcus pneumoniae D39	54.496	100	0.563
clpE	Streptococcus pneumoniae R6	54.496	100	0.563
clpE	Streptococcus pneumoniae TIGR4	54.434	100	0.562
clpC	Bacillus subtilis subsp. subtilis str. 168	55.431	88.169	0.489
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.554	92.113	0.438
clpC	Streptococcus thermophilus LMD-9	45.636	91.972	0.42
clpC	Streptococcus thermophilus LMG 18311	45.482	91.972	0.418
clpC	Streptococcus pneumoniae TIGR4	44.854	91.69	0.411
clpC	Streptococcus pneumoniae Rx1	45.383	90	0.408
clpC	Streptococcus pneumoniae D39	45.383	90	0.408
clpC	Streptococcus mutans UA159	46.764	87.042	0.407