Detailed information NTG0040539

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SSUST3_RS02660
• Genome accession: NC_015433
• Coordinates: 507208..509436 (-)
• Length: 742 a.a.
• NCBI ID: WP_013730209.1
• Uniprot ID: -
• Organism: Streptococcus suis ST3
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 502208..514436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUST3_RS02645 (SSUST3_0511)	-	504419..505621 (-)	1203	WP_009909264.1	IS110-like element ISSsu7 family transposase	-
SSUST3_RS02650 (SSUST3_0512)	-	506171..506506 (-)	336	WP_013730208.1	DUF1827 family protein	-
SSUST3_RS02655 (SSUST3_0513)	-	506561..507022 (-)	462	WP_002938708.1	NUDIX hydrolase	-
SSUST3_RS02660 (SSUST3_0514)	clpE	507208..509436 (-)	2229	WP_013730209.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SSUST3_RS02665 (SSUST3_0515)	-	509660..509890 (+)	231	WP_002938704.1	DUF1797 family protein	-
SSUST3_RS02670 (SSUST3_0516)	-	510016..510705 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
SSUST3_RS02675 (SSUST3_0517)	-	510698..511432 (+)	735	WP_002938699.1	amino acid ABC transporter ATP-binding protein	-
SSUST3_RS02680 (SSUST3_0518)	-	511562..512410 (+)	849	WP_002938697.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
SSUST3_RS02685 (SSUST3_0519)	-	513848..514141 (+)	294	WP_002938694.1	hypothetical protein	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82669.02 Da
• Isoelectric Point: 5.2167

>NTDB_id=40539 SSUST3_RS02660 WP_013730209.1 507208..509436(-) (clpE) [Streptococcus suis ST3]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGEHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=40539 SSUST3_RS02660 WP_013730209.1 507208..509436(-) (clpE) [Streptococcus suis ST3]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAACATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCTACTCAAGCCGGTGAGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTAACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGGAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAACAATTAGCTATCGAACTCTTCGGTTCGGCAGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACAGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGTCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACTATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTGCGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• AAA lid domain (AAA_lid_9) (291-389)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.228	100	0.836
clpE	Streptococcus pneumoniae D39	82.228	100	0.836
clpE	Streptococcus pneumoniae R6	82.228	100	0.836
clpE	Streptococcus pneumoniae TIGR4	82.228	100	0.836
clpE	Streptococcus mutans UA159	82.243	100	0.83
clpC	Lactococcus lactis subsp. cremoris KW2	77.517	97.709	0.757
clpC	Bacillus subtilis subsp. subtilis str. 168	52.462	87.601	0.46
clpC	Streptococcus mutans UA159	48.558	84.097	0.408
clpC	Streptococcus thermophilus LMD-9	48.248	84.636	0.408
clpC	Streptococcus thermophilus LMG 18311	47.93	84.636	0.406
clpC	Streptococcus pneumoniae TIGR4	47.84	84.232	0.403
clpC	Streptococcus pneumoniae Rx1	47.84	84.232	0.403
clpC	Streptococcus pneumoniae D39	47.84	84.232	0.403
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.815	84.636	0.396