Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GOM46_RS05940 Genome accession   NZ_CP046525
Coordinates   1180475..1182724 (+) Length   749 a.a.
NCBI ID   WP_049530939.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1175475..1187724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS05910 (GOM46_05900) - 1176220..1176405 (+) 186 WP_006149832.1 hypothetical protein -
  GOM46_RS05915 (GOM46_05905) - 1176429..1177277 (-) 849 WP_006149957.1 NAD(P)H-hydrate dehydratase -
  GOM46_RS05920 (GOM46_05910) - 1177394..1178251 (-) 858 WP_006149835.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  GOM46_RS05925 (GOM46_05915) - 1178389..1179123 (-) 735 WP_006145885.1 amino acid ABC transporter ATP-binding protein -
  GOM46_RS05930 (GOM46_05920) - 1179123..1179806 (-) 684 WP_006149889.1 amino acid ABC transporter permease -
  GOM46_RS05935 (GOM46_05925) - 1180005..1180235 (+) 231 WP_004253825.1 DUF1797 family protein -
  GOM46_RS05940 (GOM46_05930) clpE 1180475..1182724 (+) 2250 WP_049530939.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GOM46_RS05945 (GOM46_05935) - 1182814..1183263 (+) 450 WP_235083329.1 NUDIX hydrolase -
  GOM46_RS05950 (GOM46_05940) - 1183327..1183626 (+) 300 WP_006149955.1 DUF1827 family protein -
  GOM46_RS05955 (GOM46_05945) - 1183815..1184447 (+) 633 WP_006149873.1 GNAT family N-acetyltransferase -
  GOM46_RS05960 (GOM46_05950) metK 1184493..1185683 (-) 1191 WP_006149959.1 methionine adenosyltransferase -
  GOM46_RS05965 (GOM46_05955) - 1185922..1186620 (-) 699 WP_006149854.1 GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 749 a.a.        Molecular weight: 83393.62 Da        Isoelectric Point: 5.1677

>NTDB_id=405078 GOM46_RS05940 WP_049530939.1 1180475..1182724(+) (clpE) [Streptococcus infantis strain SO]
MLCQNCKINDSTIHLYTNLNGQQKQIDLCQNCYKIIKTDPNNSLFKGITDLNNRDFDPFGDFFNDLNNFRPSSNSNTPPT
QSGGGYGGNGGYGSQNRGPAQTPPPSQEKGLLDEYGINVTEIARRGNIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRKDVILFIDEIHEIVGAGSAG
EGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGIQKKYEDYHHVHYTDGAI
EAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KTKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLINLADDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFD
GIIEFKALSKENLLQIVDLMLDDVNKRLSSNNIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENPS
EKDLKAVMTSKGKIVIKSKNKTETVESND

Nucleotide


Download         Length: 2250 bp        

>NTDB_id=405078 GOM46_RS05940 WP_049530939.1 1180475..1182724(+) (clpE) [Streptococcus infantis strain SO]
ATGCTCTGTCAAAATTGTAAAATCAATGACTCAACAATCCATCTTTACACTAATCTGAATGGGCAACAAAAGCAAATCGA
TCTTTGCCAAAATTGCTACAAAATTATCAAAACAGATCCTAACAATAGCTTATTTAAAGGAATTACAGATTTAAACAATC
GTGATTTCGATCCATTTGGAGATTTCTTTAACGACCTGAACAACTTTAGACCTTCTTCTAATAGCAATACTCCTCCTACC
CAGTCAGGTGGTGGATACGGCGGTAATGGTGGCTATGGTTCCCAAAATCGTGGACCGGCTCAAACTCCTCCTCCTAGTCA
GGAAAAAGGACTCTTGGATGAATATGGTATCAATGTTACTGAGATTGCCCGTCGTGGAAATATCGACCCTGTGATTGGTC
GTGACGAAGAAATCATCCGCGTTATTGAAATTCTCAACCGTAGAACCAAAAACAACCCTGTCCTTATCGGTGAGCCTGGT
GTTGGTAAGACAGCCGTTGTCGAGGGCTTAGCTCAGAAAATTGTTGATGGTGATGTTCCCCATAAACTTCAAGGGAAAGA
AGTCATTCGCCTAGATGTTGTCAGCCTTGTCCAAGGTACAGGAATTCGTGGACAGTTCGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTAAGCGTAAAGATGTCATCCTCTTCATTGACGAAATTCACGAAATCGTCGGTGCTGGTTCTGCTGGA
GAAGGAAATATGGATGCAGGAAATATCCTCAAACCAGCTCTTGCTCGCGGCGAACTCCAACTAGTTGGTGCTACTACCCT
CAATGAATATCGCATCATCGAAAAAGATGCAGCCCTTGAGCGCCGTATGCAACCTGTCAAAGTTGATGAACCAACTGTGG
AAGAGACTATTATTATTCTTAAAGGTATTCAAAAGAAATACGAAGATTACCACCACGTTCATTATACTGACGGAGCTATC
GAAGCAGCTGCTACTCTCTCTAACCGCTATATCCAAGATCGTTTCTTGCCGGATAAGGCCATTGACCTCCTAGATGAAGC
TGGTTCTAAAATGAACTTAACCTTAAATTTTGTGGATCCAAAGGTCATCGACCAACGTTTAATCGAAGCAGAAAATCTCA
AGGCACAAGCAACCCGCGATGAAGACTTTGAAAAAGCAGCCTACTTCCGTGACCAGATTGCTAAATATAAGGAAATGCAA
AAGACCAAGGTAACGGATCAGGATACCCCAATCATCAGTGAAAAAACAATCGAACACATCATCGAACAAAAGACCAATAT
CCCAGTTGGTGATTTGAAAGAAAAAGAACAGTCTCAACTGATCAACCTAGCAGATGACCTCAAGGCTCATGTTATTGGTC
AAGATGATGCTGTCGATAAGATTGCTAAGGCTATCCGTCGTAACCGTGTTGGGCTTGGAACACCAAACCGTCCAATTGGT
AGCTTCCTCTTTGTTGGTCCTACAGGTGTCGGTAAAACAGAACTCTCTAAACAACTGGCCATCGAACTCTTTGGTTCTGC
TGATAGCATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGCGTTGCTAAACTCGTCGGTGCTCCTCCAGGAT
ACGTCGGCTATGATGAGGCTGGACAATTGACTGAAAAGGTTCGTCGTAACCCCTACTCACTGATCCTCTTGGATGAAGTT
GAAAAAGCCCATCCAGATGTTATGCATATGTTCCTTCAAGTCTTGGATGATGGTCGTTTAACAGATGGTCAAGGTCGGAC
TGTTAGCTTTAAGGATGCCATCATTATCATGACCTCAAATGCAGGTACAGGTAAGGCAGAAGCTAGCGTTGGTTTTGGTG
CTGCTAGAGAAGGTCGTACCAACTCTGTTCTTGGAGAATTAGGCAACTTCTTTAGTCCAGAATTCATGAACCGTTTTGAC
GGCATTATCGAATTCAAGGCTCTCAGCAAGGAAAATCTCCTTCAAATCGTTGACCTCATGCTAGATGATGTGAATAAGCG
ACTTTCCAGCAATAATATCCATCTCGATGTCACAGAAAAGGTCAAAGAAAAACTTGTAGACCTTGGTTACGATCCAAAAA
TGGGAGCTCGTCCACTCCGTCGTACCATCCAAGACTATATCGAAGATGCCATTACAGACTACTACCTTGAAAATCCTAGT
GAAAAAGACCTCAAGGCAGTCATGACAAGTAAAGGTAAAATCGTGATTAAGTCCAAAAATAAAACGGAAACGGTCGAGTC
AAACGACTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-722)

ATPase family associated with various cellular activities (AAA) (AAA)

(154-272)

AAA lid domain (AAA_lid_9)

(292-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.251

99.866

0.941
  clpE Streptococcus pneumoniae D39

94.251

99.866

0.941
  clpE Streptococcus pneumoniae R6

94.251

99.866

0.941
  clpE Streptococcus pneumoniae TIGR4

94.118

99.866

0.94
  clpE Streptococcus mutans UA159

83.845

100

0.838
  clpC Lactococcus lactis subsp. cremoris KW2

76.72

100

0.774
  clpC Bacillus subtilis subsp. subtilis str. 168

50.718

92.924

0.471
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.166

83.712

0.403
  clpC Streptococcus pneumoniae TIGR4

47.134

83.845

0.395
  clpC Streptococcus pneumoniae Rx1

47.134

83.845

0.395
  clpC Streptococcus pneumoniae D39

47.134

83.845

0.395
  clpC Streptococcus thermophilus LMD-9

46.955

83.311

0.391
  clpC Streptococcus thermophilus LMG 18311

46.635

83.311

0.389
  clpC Streptococcus mutans UA159

46.411

83.712

0.389

Multiple sequence alignment