Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GOM47_RS06865 Genome accession   NZ_CP046524
Coordinates   1346783..1349041 (+) Length   752 a.a.
NCBI ID   WP_235080302.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1341783..1354041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS06835 (GOM47_06825) - 1342568..1343341 (-) 774 WP_235080297.1 HAD hydrolase family protein -
  GOM47_RS06840 (GOM47_06830) - 1343346..1344203 (-) 858 WP_235080298.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  GOM47_RS06845 (GOM47_06835) - 1344352..1344672 (-) 321 WP_235080299.1 TfoX/Sxy family protein -
  GOM47_RS06850 (GOM47_06840) - 1344706..1345440 (-) 735 WP_000140925.1 amino acid ABC transporter ATP-binding protein -
  GOM47_RS06855 (GOM47_06845) - 1345440..1346123 (-) 684 WP_235080300.1 amino acid ABC transporter permease -
  GOM47_RS06860 (GOM47_06850) - 1346314..1346544 (+) 231 WP_235080301.1 DUF1797 family protein -
  GOM47_RS06865 (GOM47_06855) clpE 1346783..1349041 (+) 2259 WP_235080302.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GOM47_RS06870 (GOM47_06860) - 1349172..1349624 (+) 453 WP_235080303.1 NUDIX hydrolase -
  GOM47_RS06875 (GOM47_06865) - 1349683..1349982 (+) 300 WP_173258722.1 DUF1827 family protein -
  GOM47_RS06880 (GOM47_06870) metK 1350049..1351239 (-) 1191 WP_235080304.1 methionine adenosyltransferase -
  GOM47_RS06885 (GOM47_06880) - 1352201..1352861 (+) 661 Protein_1312 IS30 family transposase -
  GOM47_RS06890 (GOM47_06885) ftsX 1352982..1353908 (-) 927 WP_235080305.1 permease-like cell division protein FtsX -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83969.35 Da        Isoelectric Point: 5.1791

>NTDB_id=404999 GOM47_RS06865 WP_235080302.1 1346783..1349041(+) (clpE) [Streptococcus oralis strain SOT]
MLCQNCKINDSTIHLYTNINGQQKQIDLCQNCYKIIKTDPNNTLFKGMTDLNNHDFDPFGDFFNDLNNFKPSSNNIPPTQ
SGGGYGGNGGYGPQNRGPLQTPPSQERGLLEEYGINVTEIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDAAIEA
AANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKEMQKN
KVTDQDTPIISEKTIEHIIEQKTNIPVGELKEKEQSQLIHLAEDLKAHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGRAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKPLSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYNPKMGARPLRRTIQDHIEDAITDYYLENPSEK
DLKAVMTSNGKIQIKSAKKTEKTEEIASEKEE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=404999 GOM47_RS06865 WP_235080302.1 1346783..1349041(+) (clpE) [Streptococcus oralis strain SOT]
ATGCTCTGTCAAAACTGTAAAATTAACGACTCAACAATTCATCTGTATACCAATATCAATGGACAGCAAAAGCAAATTGA
TCTCTGTCAAAATTGCTATAAAATTATCAAAACAGATCCAAATAATACCCTCTTTAAAGGAATGACTGACTTAAATAATC
ATGACTTTGATCCATTCGGCGACTTTTTCAATGACTTGAACAATTTCAAACCTTCTTCTAATAACATCCCTCCAACTCAA
TCTGGTGGGGGATATGGAGGAAACGGTGGTTATGGACCTCAAAACCGCGGCCCACTTCAAACACCTCCTAGCCAAGAAAG
AGGACTCCTAGAGGAATATGGTATCAACGTAACTGAGATTGCTCGTCGGGGAGATATTGACCCTGTTATCGGTCGAGATG
AGGAGATTATCCGCGTTATCGAAATCCTCAACCGAAGAACCAAGAACAACCCTGTCCTTATCGGAGAACCAGGTGTTGGT
AAAACAGCCGTTGTCGAAGGTTTAGCTCAGAAGATTGTCGATGGCGATGTTCCCCATAAACTCCAAGGCAAGCAAGTTAT
CCGTTTGGATGTGGTCAGTCTAGTCCAAGGAACTGGTATCCGTGGCCAATTTGAAGAGCGTATGCAAAAGCTCATGGAAG
AAATCCGCAAACGCGAGGACATCATTCTCTTTATCGATGAAATCCATGAAATTGTCGGTGCAGGATCTGCTGGCGATGGC
AATATGGATGCAGGAAATATCCTCAAACCTGCCCTTGCCCGTGGTGAATTGCAACTGGTCGGTGCCACTACTCTCAATGA
ATACCGTATCATTGAAAAAGATGCTGCTCTAGAGCGCCGTATGCAGCCTGTCAAGGTAGATGAACCAACTGTCGAAGAAA
CCATTACCATCCTCAAAGGGATTCAAAAGAAATACGAAGACTACCATCACGTCAAGTACACAGACGCTGCTATTGAAGCT
GCTGCAAATCTTTCCAACCGCTACATCCAAGACCGTTTCTTACCTGACAAGGCTATTGACCTTTTAGACGAAGCCGGTTC
AAAGATGAATTTGACGCTGAACTTTGTTGATCCTAAAGTAATTGACCAACGTTTAATTGAAGCTGAGAATCTCAAGGCTC
AAGCTACACGAGAGGAAGACTTTGAAAAAGCTGCCTACTTCCGTGATCAGATTGCCAAGTACAAGGAAATGCAAAAGAAC
AAGGTGACCGATCAGGATACTCCAATCATCAGCGAGAAAACGATTGAACATATCATCGAGCAGAAAACCAATATCCCTGT
TGGGGAGCTAAAAGAAAAAGAACAGTCTCAATTGATCCATCTAGCAGAAGACCTCAAGGCCCATGTTATCGGACAAGATG
AGGCTGTCGATAAGATTGCAAAAGCCATCCGTCGAAATCGTGTTGGACTTGGAACTCCTAACCGCCCAATCGGAAGCTTC
CTCTTTGTCGGACCAACTGGTGTCGGTAAGACAGAACTGTCCAAACAACTAGCTATCGAACTCTTTGGTTCTGCTGACAG
CATGATTCGCTTTGACATGAGCGAATACATGGAAAAACACAGCGTTGCTAAATTAGTCGGTGCCCCTCCAGGTTATGTAG
GCTACGATGAAGCGGGTCAATTAACAGAAAAAGTTCGTCGCAATCCCTACTCTCTCATCCTTCTCGATGAAGTCGAAAAA
GCCCATCCAGATGTGATGCACATGTTCCTTCAGGTCTTGGACGATGGTCGTTTGACTGATGGGCAAGGACGTACAGTTAG
CTTTAAGGATGCCATCATCATCATGACCTCAAATGCGGGTACTGGTAGGGCCGAAGCCAGTGTTGGTTTTGGAGCTGCTC
GTGAAGGTCGAACCAACTCTGTTCTCGGTGAACTCGGTAACTTCTTTAGCCCAGAGTTTATGAACCGTTTTGACGGCATC
ATCGAATTTAAACCTCTCAGCAAGGACAACCTCCTCCAAATCGTCGAACTCATGCTAGCGGATGTCAACAAACGCCTCTC
TAGCAACAATATCCACCTCGATGTGACAGACAAGGTCAAGGAAAAGTTGGTTGACTTGGGATATAATCCAAAAATGGGGG
CACGGCCACTCCGTCGTACCATTCAAGACCATATCGAGGATGCTATCACAGACTACTACCTTGAAAACCCAAGTGAAAAA
GACCTCAAGGCAGTTATGACAAGCAATGGCAAGATTCAAATTAAATCTGCCAAAAAAACTGAAAAAACAGAAGAGATTGC
TTCTGAAAAAGAAGAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-720)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA lid domain (AAA_lid_9)

(290-387)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.305

100

0.947
  clpE Streptococcus pneumoniae D39

94.305

100

0.947
  clpE Streptococcus pneumoniae R6

94.305

100

0.947
  clpE Streptococcus pneumoniae TIGR4

94.172

100

0.945
  clpE Streptococcus mutans UA159

83.156

100

0.834
  clpC Lactococcus lactis subsp. cremoris KW2

75.794

100

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

52.308

86.436

0.452
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.546

86.702

0.412
  clpC Streptococcus thermophilus LMD-9

46.751

83.91

0.392
  clpC Streptococcus pneumoniae Rx1

47.343

82.58

0.391
  clpC Streptococcus pneumoniae D39

47.343

82.58

0.391
  clpC Streptococcus pneumoniae TIGR4

47.343

82.58

0.391
  clpC Streptococcus thermophilus LMG 18311

46.508

83.777

0.39
  clpC Streptococcus mutans UA159

46.508

83.777

0.39

Multiple sequence alignment