Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   GOM47_RS01395 Genome accession   NZ_CP046524
Coordinates   254306..255130 (+) Length   274 a.a.
NCBI ID   WP_235080833.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 249306..260130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS01360 (GOM47_01355) asnA 249396..250388 (+) 993 WP_061409759.1 aspartate--ammonia ligase -
  GOM47_RS01365 (GOM47_01360) rsmD 250453..250992 (+) 540 WP_235080829.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  GOM47_RS01370 (GOM47_01365) coaD 250982..251470 (+) 489 WP_235080830.1 pantetheine-phosphate adenylyltransferase -
  GOM47_RS01375 (GOM47_01370) sepM 251454..252491 (+) 1038 WP_235080831.1 SepM family pheromone-processing serine protease Regulator
  GOM47_RS01380 (GOM47_01375) - 252547..252777 (+) 231 WP_002892633.1 DUF1146 family protein -
  GOM47_RS01385 (GOM47_01380) murA 252801..254084 (+) 1284 WP_235080832.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GOM47_RS01390 (GOM47_01385) - 254071..254265 (+) 195 WP_061415718.1 DNA-directed RNA polymerase subunit beta -
  GOM47_RS01395 (GOM47_01390) endA 254306..255130 (+) 825 WP_235080833.1 DNA/RNA non-specific endonuclease Machinery gene
  GOM47_RS01400 (GOM47_01395) - 255271..256602 (+) 1332 WP_235080834.1 hemolysin family protein -
  GOM47_RS01410 (GOM47_01405) amiA 257130..259109 (+) 1980 WP_235080835.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29954.67 Da        Isoelectric Point: 9.9134

>NTDB_id=404973 GOM47_RS01395 WP_235080833.1 254306..255130(+) (endA) [Streptococcus oralis strain SOT]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQTAPNTPRTKVSQKKQASEAPSQELAESVLTESIKNQIKGGLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVIN

Nucleotide


Download         Length: 825 bp        

>NTDB_id=404973 GOM47_RS01395 WP_235080833.1 254306..255130(+) (endA) [Streptococcus oralis strain SOT]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTATATCAAGCA
GATGCAGACAGCGCCAAACACCCCTAGAACTAAGGTTAGTCAGAAAAAGCAAGCTTCAGAAGCTCCCAGTCAGGAGCTGG
CTGAAAGTGTCTTAACTGAGTCAATCAAAAACCAAATCAAGGGGGGACTCGAGTGGAATGGAGCAGGGGCCTTCATTGTC
AATGGCAATAAGACCAATCTAGATGCCAAGGTTTCTAGCAAACCCTATGCGGATAATAAGACAAAGACAGTGGGAAAAGA
AACAGTTCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAAACAGGAAATGGAT
CCACCTCTTGGACGCCACCAGGATGGCATCAGGTTAAAAATCTAAAGGGAGCCTACACACATGCAGTTGATAGAGGACAC
CTGCTAGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCGAATCAAGCGCAAGCTGAGGATTCGACTGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AGAATAAGAGAGTCCGTTATCGGGTAACTCTCCACTATGCGACAAATGAGGATCTAGTTCCGTCCGCTTCACAAATTGAA
GCCAAGTCTTCGGATGGCGAGTTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGTATCCAGCTTGACTACCGAAC
AGGTCAAGTTACGGTGATAAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.338

99.27

0.887
  endA Streptococcus pneumoniae D39

89.338

99.27

0.887
  endA Streptococcus pneumoniae R6

89.338

99.27

0.887
  endA Streptococcus pneumoniae TIGR4

89.338

99.27

0.887

Multiple sequence alignment