Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   GOM48_RS09505 Genome accession   NZ_CP046523
Coordinates   1889551..1891983 (-) Length   810 a.a.
NCBI ID   WP_235097535.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1884551..1896983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS09480 (GOM48_09415) - 1884982..1885668 (-) 687 WP_235097525.1 YoaK family protein -
  GOM48_RS09485 (GOM48_09420) - 1885795..1886478 (-) 684 WP_235097527.1 hypothetical protein -
  GOM48_RS09490 (GOM48_09425) - 1886783..1887556 (-) 774 WP_235097529.1 NUDIX domain-containing protein -
  GOM48_RS09495 (GOM48_09430) pnuC 1887558..1888337 (-) 780 WP_235097532.1 nicotinamide riboside transporter PnuC -
  GOM48_RS09500 (GOM48_09435) - 1888347..1889405 (-) 1059 WP_235097533.1 AAA family ATPase -
  GOM48_RS09505 (GOM48_09440) clpC 1889551..1891983 (-) 2433 WP_235097535.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GOM48_RS09510 (GOM48_09445) - 1891985..1892443 (-) 459 WP_001211258.1 CtsR family transcriptional regulator -
  GOM48_RS09515 (GOM48_09450) - 1892562..1893290 (-) 729 WP_235097537.1 ABC transporter ATP-binding protein -
  GOM48_RS09520 (GOM48_09455) - 1893290..1894297 (-) 1008 WP_235097539.1 ABC transporter substrate-binding protein -
  GOM48_RS09525 (GOM48_09460) - 1894336..1895094 (-) 759 WP_235097541.1 ABC transporter permease -
  GOM48_RS09530 (GOM48_09465) - 1895057..1895293 (-) 237 WP_235098771.1 MTH1187 family thiamine-binding protein -

Sequence

Protein


Download         Length: 810 a.a.        Molecular weight: 90360.20 Da        Isoelectric Point: 5.9338

>NTDB_id=404948 GOM48_RS09505 WP_235097535.1 1889551..1891983(-) (clpC) [Streptococcus oralis strain SOD]
MNYSKALNECIESAYMVASHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVTDKQNSMANMMGMPQAQSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGILRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADESDLTPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRIFEELKKTYRPEFINRIDEKVVFHSLDS
EHMQEIVKIMVKPLIASLAEKGIDLKLQASALKLLASQGYNPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

Nucleotide


Download         Length: 2433 bp        

>NTDB_id=404948 GOM48_RS09505 WP_235097535.1 1889551..1891983(-) (clpC) [Streptococcus oralis strain SOD]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAGAGTGCCTACATGGTTGCGAGCCATTTTGGAGCTCGTTACCTAGA
GTCATGGCACTTGTTGATTGCCATGTCCAATCACAGTTACAGCGTGGCAGGTGCGACTTTAAATGATTATCCTTATGAAA
TGGACCGTCTAGAAGAGGTTGCTTTAGAACTGACTGAAACGGACTATAGCCAGGACGAAACCTTTACGGAATTGCCTTTT
TCTCATCGTTTGGAGGTCCTATTTGCAGAAGCAGAGTATGTGGCCTCAGTGGTCCATGCAAAGGTGCTAGGGACAGAGCA
TGTTCTCTATGCGATTTTGCATGATGGCAATGCCTTGGCAACTCGCATCTTGGAGAGAGCAGGCTTCTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCCGCTCTTCGTCGCAATCTAGAAGAGCGTGCAGGATGGACTCGTGAAGACCTTAAGGCT
TTGCGTCAACGCCATCGCACAGTAACTGACAAGCAAAATTCCATGGCCAATATGATGGGCATGCCTCAAGCTCAAAGTGG
AGGCCTAGAGGATTACACGCATGACCTGACGGAGCAAGCGCGCTCTGGCAAGTTAGAGCCAGTTATCGGTCGTGACAAGG
AAATCTCACGTATGATTCAGATTTTGAGTCGTAAGACCAAGAACAATCCTGTCTTGGTTGGTGATGCTGGTGTTGGGAAA
ACAGCTCTGGCACTTGGACTTGCCCAGCGTATTGCTAGTGGGGACGTACCTGCAGAAATGGCAAAGATGCGTGTTCTAGA
GCTTGATTTGATGAATGTTGTTGCAGGGACACGTTTCCGTGGTGACTTTGAAGAACGTATGAACAACATCATCAAGGATA
TAGAGGAAGATGGCAAAGTGATTCTCTTTATCGATGAACTCCACACCATTATGGGTTCTGGAAGCGGTATTGACTCGACT
CTGGATGCGGCCAATATCTTGAAACCAGCCTTGGCGCGTGGAATTTTGAGAACGGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGATGCTGCCCTTTCTCGTCGTTTTGCAAAAGTGACGATTGAAGAGCCAAGTCTAGCTGACA
GTATGACTATTTTGCAAGGTTTGAAGGCTACCTATGAGAAACACCACCGTGTGCAAATCACAGATGAAGCTGTTGAAACA
GCTGTTAAGATGGCGCATCGTTACTTGACCAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTAGATGAGGCGGCAGC
AACAGTGCAAAACAAATCCAAGCATGTGAAAGCAGACGAATCCGACTTGACTCCAGCTGACAAGGCACTTATGGATGGCA
AGTGGAAACAGGCAGCCCAGCTAATCGCAAAAGAAGAGGAAGTACCTGTCTACAAAGACTTGGTGACAGAGTCTGATATT
TTGACTACCTTGAGTCGCTTGTCAGGTATTCCAGTCCAAAAACTGACTCAAACGGATGCTAAGAAATACCTGAACTTGGA
AGCTGAACTACACAAACGTGTCATCGGTCAAGATCAAGCTGTTTCAAGTATTAGCCGTGCCATTCGCCGCAATCAGTCAG
GTATTCGTAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGGCCGACAGGAGTCGGTAAGACCGAATTGGCAAAG
GCTCTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTTGCGGC
TAGCCGTCTCAATGGAGCACCTCCTGGCTATGTGGGCTACGAGGAAGGTGGGGAGTTGACTGAGAAGGTTCGCAACAAAC
CTTACTCAGTGCTTCTCTTTGACGAGGTAGAAAAGGCCCATCCAGACATCTTTAATGTCCTCTTGCAGGTTTTGGACGAC
GGTGTCTTGACAGATAGCAAGGGGCGCAAGGTTGATTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
GGCTCTTCGTGATGACAAGACTGTTGGCTTTGGCGCGAAAGACATTCGTTTTGACCAGGAAAATATGGAAAAACGAATCT
TTGAAGAGTTGAAAAAAACTTATCGACCAGAGTTTATCAACCGTATTGATGAAAAGGTGGTTTTCCACAGTTTGGATAGC
GAACACATGCAAGAAATTGTCAAGATTATGGTGAAACCATTGATTGCTAGCCTGGCAGAGAAGGGTATCGACCTGAAACT
GCAAGCTTCAGCCCTGAAGTTGCTAGCTAGCCAAGGTTACAATCCAGAAATGGGAGCTCGCCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAGGACAAGTTGGCAGAACTTCTTCTTAAGGGAGAACTGGTAGCAGGCAAGACACTCAAGATTGGTGTC
AAAGCTGGTCAACTAAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(718-797)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(103-133)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-49)

AAA domain (Cdc48 subfamily) (AAA_2)

(540-711)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-344)

AAA lid domain (AAA_lid_9)

(371-446)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

96.667

100

0.967
  clpC Streptococcus pneumoniae D39

96.667

100

0.967
  clpC Streptococcus pneumoniae TIGR4

96.667

100

0.967
  clpC Streptococcus mutans UA159

67.774

100

0.68
  clpC Streptococcus thermophilus LMD-9

66.83

100

0.672
  clpC Streptococcus thermophilus LMG 18311

66.708

100

0.67
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

49.275

100

0.504
  clpC Bacillus subtilis subsp. subtilis str. 168

44.828

100

0.449
  clpE Streptococcus mutans UA159

48.71

76.543

0.373
  clpC Lactococcus lactis subsp. cremoris KW2

46.89

77.407

0.363

Multiple sequence alignment