Detailed information NTG0404931

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: GOM48_RS07780
• Genome accession: NZ_CP046523
• Coordinates: 1542519..1544672 (+)
• Length: 717 a.a.
• NCBI ID: WP_235097043.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOD
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1537519..1549672

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM48_RS07745 (GOM48_07685)	ccrZ	1537614..1538408 (-)	795	WP_000363015.1	cell cycle regulator CcrZ	-
GOM48_RS07750 (GOM48_07690)	-	1538571..1538993 (-)	423	Protein_1504	lysostaphin resistance A-like protein	-
GOM48_RS07755 (GOM48_07695)	-	1539663..1539857 (-)	195	WP_235097038.1	hypothetical protein	-
GOM48_RS07760 (GOM48_07700)	-	1539915..1540100 (-)	186	WP_235097039.1	bacteriocin class II family protein	-
GOM48_RS07765 (GOM48_07705)	-	1540408..1541412 (-)	1005	WP_235097040.1	thioredoxin domain-containing protein	-
GOM48_RS07770 (GOM48_07710)	-	1541573..1541977 (-)	405	WP_235097041.1	immunity protein	-
GOM48_RS07775 (GOM48_07715)	-	1541997..1542233 (-)	237	WP_235097042.1	Blp family class II bacteriocin	-
GOM48_RS07780 (GOM48_07720)	comA/nlmT	1542519..1544672 (+)	2154	WP_235097043.1	peptide cleavage/export ABC transporter BlpA	Regulator
GOM48_RS07785 (GOM48_07725)	-	1544683..1546044 (+)	1362	WP_235097044.1	bacteriocin secretion accessory protein	-
GOM48_RS07790 (GOM48_07730)	blpC	1546101..1546256 (+)	156	WP_235097045.1	quorum-sensing system pheromone BlpC	-
GOM48_RS07795 (GOM48_07735)	-	1546299..1547639 (-)	1341	WP_235097046.1	sensor histidine kinase	-
GOM48_RS07800 (GOM48_07740)	comE/blpR	1547653..1548390 (-)	738	WP_235097047.1	response regulator transcription factor	Regulator
GOM48_RS07805 (GOM48_07745)	-	1548395..1548733 (-)	339	WP_235097048.1	LytTR family DNA-binding domain-containing protein	-
GOM48_RS07810 (GOM48_07750)	-	1549013..1549342 (+)	330	WP_235097049.1	helicase BlpT	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80694.68 Da
• Isoelectric Point: 7.4090

>NTDB_id=404931 GOM48_RS07780 WP_235097043.1 1542519..1544672(+) (comA/nlmT) [Streptococcus oralis strain SOD]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADQTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLITYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISIGLVITYILQQVMGFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGAVLLAQNPNLFLLSLISIPIYVF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTNLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQAPENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNNMISQEDILKACELAEIRQDIEKMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=404931 GOM48_RS07780 WP_235097043.1 1542519..1544672(+) (comA/nlmT) [Streptococcus oralis strain SOD]
ATGACTTCTTATAAACGTACATTTGTTCCACAAATAGATGCTAGAGACTGTGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGATTTGAAACAAGGCCTGTTCAAGCAGATCAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATTGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTACTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAGTATATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAATCGGTCTAGTTA
TCACTTATATCCTCCAACAAGTCATGGGCTTCTCCCGTGATTATCTCCTAACTGTTCTGAGTCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGGGAAATCATTTC
ACGGTTCACAGATGCCAACTCTATCATAGATGCCTTGGCTTCTACCATTCTCTCTCTTTTTCTTGATGTTTCCATTCTGA
TTCTTGTAGGGGCTGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACGTGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAATGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAATTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTCCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAGTTCCAAGCCCCAGAAAACCCTGTTCATTCGCATTTTTTG
ATGGGAGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACTTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAATATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGATCTATTTTGGAAAACTTAACCTTGGGCGGTAATAATATGATTAG
CCAAGAAGATATTCTAAAAGCTTGTGAATTAGCCGAAATCCGTCAAGATATCGAAAAAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGCTTATCTGGAGGACAAAAGCAACGAATCGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTAATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGCAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.028	99.721	0.718
comA	Streptococcus mitis NCTC 12261	66.199	99.442	0.658
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653
comA	Streptococcus pneumoniae Rx1	65.638	99.442	0.653
comA	Streptococcus pneumoniae D39	65.638	99.442	0.653
comA	Streptococcus pneumoniae R6	65.638	99.442	0.653
comA	Streptococcus mitis SK321	65.638	99.442	0.653
comA	Streptococcus pneumoniae TIGR4	65.358	99.442	0.65