Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GOM48_RS06815 Genome accession   NZ_CP046523
Coordinates   1343311..1345569 (+) Length   752 a.a.
NCBI ID   WP_235096587.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1338311..1350569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS06785 (GOM48_06775) - 1339096..1339869 (-) 774 WP_000673624.1 HAD hydrolase family protein -
  GOM48_RS06790 (GOM48_06780) - 1339874..1340731 (-) 858 WP_235096583.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  GOM48_RS06795 (GOM48_06785) - 1340881..1341201 (-) 321 WP_235096584.1 TfoX/Sxy family protein -
  GOM48_RS06800 (GOM48_06790) - 1341235..1341969 (-) 735 WP_235096585.1 amino acid ABC transporter ATP-binding protein -
  GOM48_RS06805 (GOM48_06795) - 1341969..1342652 (-) 684 WP_235096586.1 amino acid ABC transporter permease -
  GOM48_RS06810 (GOM48_06800) - 1342843..1343073 (+) 231 WP_000443579.1 DUF1797 family protein -
  GOM48_RS06815 (GOM48_06805) clpE 1343311..1345569 (+) 2259 WP_235096587.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GOM48_RS06820 (GOM48_06810) - 1345701..1346153 (+) 453 WP_000013078.1 NUDIX hydrolase -
  GOM48_RS06825 (GOM48_06815) - 1346212..1346511 (+) 300 WP_173258722.1 DUF1827 family protein -
  GOM48_RS06830 (GOM48_06820) metK 1346578..1347768 (-) 1191 WP_235096588.1 methionine adenosyltransferase -
  GOM48_RS06835 (GOM48_06830) - 1348112..1349455 (-) 1344 WP_038804977.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 84053.46 Da        Isoelectric Point: 5.1298

>NTDB_id=404927 GOM48_RS06815 WP_235096587.1 1343311..1345569(+) (clpE) [Streptococcus oralis strain SOD]
MLCQNCKINDSTIHLYTNINGQQKQIDLCQNCYKIIKTDPNNTLFKGMTDLNNRDFDPFGDFFNDLNNFRPSSNNIPPTQ
SGDGHGGNGGYGLQNRGPLQTPPSQERGLLEEYGINITEIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDAAIEA
AANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKEMQKN
KVTDQDTPIISEKTIEHIIEQKTNIPVGELKEKEQSQLIHLADDLKTHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPSEK
DLKAVMTSNGKIQIKSAKKTEKTEEIASEKEE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=404927 GOM48_RS06815 WP_235096587.1 1343311..1345569(+) (clpE) [Streptococcus oralis strain SOD]
ATGCTCTGTCAAAACTGTAAAATTAACGACTCAACAATTCATCTGTATACCAATATCAATGGACAGCAAAAGCAAATTGA
TCTCTGTCAAAATTGCTATAAAATTATCAAAACAGACCCAAACAATACCCTCTTTAAAGGAATGACTGACCTAAACAATC
GTGACTTTGATCCTTTCGGAGACTTTTTCAATGATTTGAACAATTTCAGACCTTCTTCTAATAACATCCCTCCCACTCAA
TCAGGTGATGGTCACGGTGGAAATGGGGGTTATGGACTTCAAAACCGCGGTCCACTTCAAACACCTCCTAGCCAAGAAAG
AGGACTCCTAGAGGAATATGGTATCAACATAACTGAGATTGCCCGTCGTGGGGATATTGACCCTGTTATCGGTCGAGATG
AGGAGATTATCCGTGTTATCGAAATCCTCAACCGTCGAACAAAAAACAATCCTGTCCTCATCGGAGAACCAGGTGTTGGT
AAAACAGCCGTTGTCGAAGGTCTGGCTCAAAAAATTGTCGATGGCGATGTTCCCCATAAACTCCAAGGTAAGCAAGTTAT
CCGTTTGGATGTGGTCAGTCTAGTTCAAGGAACAGGTATTCGAGGTCAATTTGAAGAGCGTATGCAAAAGCTCATGGAAG
AAATCCGCAAACGCGAGGACATCATTCTCTTTATCGATGAAATCCATGAAATTGTTGGTGCAGGATCTGCTGGCGATGGC
AATATGGATGCAGGAAATATCCTCAAACCTGCCCTTGCCCGTGGTGAATTGCAACTGGTCGGTGCCACTACTCTCAATGA
ATACCGTATCATTGAAAAAGATGCTGCTCTAGAGCGCCGTATGCAGCCTGTCAAGGTAGATGAGCCAACTGTTGAAGAAA
CCATTACTATCCTCAAAGGGATTCAAAAGAAATACGAAGACTACCATCATGTCAAGTACACAGACGCTGCTATCGAAGCT
GCTGCAAATCTTTCCAACCGCTATATCCAAGACCGCTTCTTGCCAGACAAGGCTATTGACCTGTTGGATGAAGCTGGTTC
TAAGATGAATCTGACACTGAACTTTGTTGATCCTAAAGTGATTGACCAGCGTTTAATTGAAGCTGAGAATCTCAAGGCTC
AGGCTACACGAGAGGAAGACTTTGAAAAGGCTGCTTATTTCCGTGATCAGATTGCCAAGTACAAGGAAATGCAAAAGAAC
AAGGTGACCGATCAGGATACTCCTATCATCAGTGAGAAAACCATTGAACATATCATTGAGCAGAAAACCAATATCCCTGT
TGGAGAACTCAAAGAAAAGGAACAATCTCAGCTTATCCATCTAGCAGACGACCTCAAAACTCATGTCATTGGTCAAGATG
AAGCTGTCGATAAGATTGCCAAAGCCATCCGTCGTAATCGTGTTGGACTTGGAACTCCTAACCGGCCAATCGGAAGCTTC
CTTTTTGTCGGACCAACTGGTGTCGGTAAAACAGAACTTTCCAAACAACTAGCCATTGAACTTTTTGGTTCTGCTGATAG
CATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGCGTGGCTAAATTAGTCGGTGCCCCTCCAGGTTATGTCG
GCTACGATGAAGCTGGGCAGCTGACTGAAAAAGTTCGTCGCAATCCTTACTCTCTCATCCTTCTCGATGAAGTCGAAAAA
GCCCATCCAGATGTCATGCACATGTTCCTTCAAGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACGAACAGTTAG
CTTTAAGGATGCTATCATTATCATGACCTCAAATGCGGGTACTGGTAAGGTCGAAGCCAGCGTTGGTTTTGGAGCTGCTC
GTGAAGGTCGAACCAACTCTGTTCTCGGTGAACTCGGCAACTTCTTTAGCCCTGAATTTATGAACCGTTTTGACGGCATC
ATCGAGTTCAAAGCTCTCAGCAAGGACAACCTTCTCCAAATCGTCGAACTCATGCTAGCAGATGTCAACAAACGCCTCTC
TAGCAACAATATCCACCTCGATGTGACAGACAAGGTCAAGGAAAAGTTGGTTGACTTGGGATATGATCCAAAAATGGGGG
CACGCCCACTCCGCCGTACCATTCAAGACCATATCGAGGATGCCATCACTGACTTCTACCTTGAAAATCCAAGTGAGAAA
GACCTCAAGGCAGTTATGACAAGCAATGGTAAGATTCAAATCAAATCTGCCAAAAAAACTGAAAAAACAGAAGAGATTGC
TTCTGAAAAAGAAGAATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(290-387)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-720)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.305

100

0.947
  clpE Streptococcus pneumoniae D39

94.305

100

0.947
  clpE Streptococcus pneumoniae R6

94.305

100

0.947
  clpE Streptococcus pneumoniae TIGR4

94.172

100

0.945
  clpE Streptococcus mutans UA159

83.952

100

0.842
  clpC Lactococcus lactis subsp. cremoris KW2

76.058

100

0.765
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

86.436

0.453
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.546

86.702

0.412
  clpC Streptococcus thermophilus LMD-9

46.751

83.91

0.392
  clpC Streptococcus pneumoniae TIGR4

47.343

82.58

0.391
  clpC Streptococcus pneumoniae Rx1

47.343

82.58

0.391
  clpC Streptococcus pneumoniae D39

47.343

82.58

0.391
  clpC Streptococcus thermophilus LMG 18311

46.508

83.777

0.39
  clpC Streptococcus mutans UA159

46.508

83.777

0.39

Multiple sequence alignment