Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GOM48_RS01530 Genome accession   NZ_CP046523
Coordinates   319334..320023 (+) Length   229 a.a.
NCBI ID   WP_235097923.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 314334..325023
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS01505 (GOM48_01495) gpsB 314389..314718 (+) 330 WP_000146526.1 cell division regulator GpsB -
  GOM48_RS01515 (GOM48_01505) - 315204..316361 (+) 1158 WP_235097919.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  GOM48_RS01520 (GOM48_01510) mapZ 316374..317822 (+) 1449 WP_235097921.1 cell division site-positioning protein MapZ -
  GOM48_RS01525 (GOM48_01515) gndA 317898..319322 (+) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  GOM48_RS01530 (GOM48_01520) covR 319334..320023 (+) 690 WP_235097923.1 DNA-binding response regulator Regulator
  GOM48_RS01535 (GOM48_01525) - 320123..321103 (+) 981 WP_235097925.1 N-acetylmuramoyl-L-alanine amidase family protein -
  GOM48_RS01540 (GOM48_01530) mvk 321221..322099 (+) 879 WP_235097927.1 mevalonate kinase -
  GOM48_RS01545 (GOM48_01535) mvaD 322081..323034 (+) 954 WP_235097929.1 diphosphomevalonate decarboxylase -
  GOM48_RS01550 (GOM48_01540) - 323021..324028 (+) 1008 WP_235097931.1 phosphomevalonate kinase -
  GOM48_RS01555 (GOM48_01545) fni 324012..325013 (+) 1002 WP_235097933.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26868.10 Da        Isoelectric Point: 8.0271

>NTDB_id=404905 GOM48_RS01530 WP_235097923.1 319334..320023(+) (covR) [Streptococcus oralis strain SOD]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGEKALSMALQIDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELRDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=404905 GOM48_RS01530 WP_235097923.1 319334..320023(+) (covR) [Streptococcus oralis strain SOD]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGGAAAAAGCCCTCTCCATGGCTCTCCAGATAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGAACCAAACCAGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCGAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACTAATATCGTGGATGTTTATATTCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACAGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment