Detailed information NTG0404865

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GE024_RS07755
• Genome accession: NZ_CP046521
• Coordinates: 1536097..1537134 (-)
• Length: 345 a.a.
• NCBI ID: WP_003044435.1
• Uniprot ID: A0AAV3FT85
• Organism: Streptococcus canis strain HL_100
• Function: processing of CSP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1534645..1535847	1536097..1537134	flank	250

Gene organization within MGE regions

Location: 1534645..1537134

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE024_RS07750 (GE024_07770)	-	1534645..1535847 (+)	1203	WP_156667764.1	IS110 family transposase	-
GE024_RS07755 (GE024_07775)	sepM	1536097..1537134 (-)	1038	WP_003044435.1	SepM family pheromone-processing serine protease	Regulator

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37690.50 Da
• Isoelectric Point: 9.7859

>NTDB_id=404865 GE024_RS07755 WP_003044435.1 1536097..1537134(-) (sepM) [Streptococcus canis strain HL_100]
MKIIKKIKWWLVSLFALVALLITLFFPLPYYVEMPGGAYDIRSVLQVNGKEDKGKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAIYQALTLANKPVTLDYKGVYVLDVSKDSTFKGALNLADTVTGVNDK
QFKSSTELVDYVSHLKLGDKVTVQFMSDSQPKSETGRIIKLKNGKNGIGIALTDHTKVRSEDKIAFSTQGVGGPSAGLMF
TLDIYDQIVKEDLRKGRIIAGTGTIGKHGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKALKKTHPKAISNYEEAKRA
AKQLKTKMKIVPVTNVQEALAYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=404865 GE024_RS07755 WP_003044435.1 1536097..1537134(-) (sepM) [Streptococcus canis strain HL_100]
ATGAAAATAATTAAAAAAATCAAATGGTGGCTGGTTAGCCTTTTTGCTCTAGTAGCTTTGCTGATTACCCTCTTTTTCCC
TCTACCTTATTACGTTGAAATGCCTGGCGGCGCTTATGATATTCGCTCTGTTTTACAAGTTAATGGAAAAGAAGATAAAG
GGAAGGGATCTTATCAATTTGTAGCCGTTAGCCTTAGCCGCGCCAGTTTGGCACAGTTATTGTATGCTTGGTTAACCCCT
TTTACCGAAATCAGTTCCGTTGAAGACACTACGGGTGGTTACAGTGATGCTGATTATATCCGCATTAACCAATTCTACAT
GGAAACCTCGCAAAATGCAGCGATCTATCAGGCATTAACCTTGGCGAACAAACCCGTTACGTTGGATTACAAAGGGGTTT
ACGTATTAGATGTTAGCAAAGACTCAACCTTCAAAGGTGCCTTGAATTTAGCAGATACTGTCACTGGTGTGAATGACAAG
CAATTTAAGAGTTCGACAGAGCTTGTGGACTATGTTTCTCATTTAAAACTTGGGGATAAAGTAACTGTTCAGTTTATGAG
TGATAGTCAGCCCAAGTCTGAGACAGGCCGTATTATTAAACTTAAAAACGGTAAAAATGGTATTGGGATTGCTCTTACAG
ACCATACTAAAGTTAGGTCAGAGGATAAGATCGCGTTTAGCACGCAAGGTGTTGGTGGTCCCAGTGCTGGTTTGATGTTT
ACCCTTGATATTTATGACCAAATTGTCAAGGAGGATCTTCGTAAAGGTCGTATCATCGCAGGTACAGGAACGATTGGCAA
ACATGGCGAAGTGGGAGATATTGGTGGCGCAGGCCTTAAAGTTGTGGCTGCCGCAGATGCTGGTGCTGAAATATTCTTTG
TTCCTAACAATCCTGTGGACAAGGCCTTAAAAAAAACGCATCCCAAAGCCATCAGCAACTATGAAGAAGCTAAGCGAGCA
GCTAAGCAATTAAAAACTAAAATGAAGATTGTGCCTGTGACCAATGTTCAGGAAGCTTTGGCTTATCTTCGGAAATGA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-304)

• PDZ domain (PDZ_2) (130-191)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.884	100	0.719