Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GE024_RS07585 Genome accession   NZ_CP046521
Coordinates   1497561..1499858 (+) Length   765 a.a.
NCBI ID   WP_093998792.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1492561..1504858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS07550 (GE024_07565) - 1492731..1493519 (-) 789 WP_003044313.1 TrmB family transcriptional regulator -
  GE024_RS11215 - 1494465..1494794 (-) 330 WP_232038585.1 GTPase -
  GE024_RS07565 (GE024_07580) - 1494791..1495272 (-) 482 Protein_1443 ferrous iron transport protein A -
  GE024_RS07570 (GE024_07585) - 1495483..1496217 (-) 735 WP_003044324.1 amino acid ABC transporter ATP-binding protein -
  GE024_RS07575 (GE024_07590) - 1496217..1496903 (-) 687 WP_093998791.1 amino acid ABC transporter permease -
  GE024_RS07580 (GE024_07595) - 1497030..1497260 (-) 231 WP_002983885.1 YkuJ family protein -
  GE024_RS07585 (GE024_07600) clpE 1497561..1499858 (+) 2298 WP_093998792.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GE024_RS07590 (GE024_07605) - 1499985..1500440 (+) 456 WP_093998793.1 NUDIX hydrolase -
  GE024_RS07595 (GE024_07610) - 1500491..1500793 (+) 303 WP_003044336.1 DUF1827 family protein -
  GE024_RS07600 (GE024_07615) tnpA 1501145..1501609 (+) 465 Protein_1450 IS200/IS605 family transposase -
  GE024_RS07605 (GE024_07620) ileS 1501780..1504581 (-) 2802 WP_093999221.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 765 a.a.        Molecular weight: 85039.25 Da        Isoelectric Point: 5.4142

>NTDB_id=404864 GE024_RS07585 WP_093998792.1 1497561..1499858(+) (clpE) [Streptococcus canis strain HL_100]
MLCQNCNLNESTIHLYTNVNGKQRQVDLCQNCYQIMKTDPTNPILGGLNRGQKAQDRSSHPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGNYNGQGQGQPQPQAPNQQAKGLLEEFGINVTDIARHGDIDPVIGRDEEITRVIEILNRRTK
NNPVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKEVILFIDEI
HEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDY
HHVKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKINLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFR
DQIAKYKEMQAQKVNEQDIPIITEKNIEAIVEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDAAVDKIAKAIRRNRV
GLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRN
PYSLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSNF
FSPEFMNRFDGIIEFKALSKDNLLHIVDLMLADVNQRLAYNNIDLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDA
ITDYYLEHPTEKDLRAVMTSNGNIMIKAAKKGETVPTTQEQDNNH

Nucleotide


Download         Length: 2298 bp        

>NTDB_id=404864 GE024_RS07585 WP_093998792.1 1497561..1499858(+) (clpE) [Streptococcus canis strain HL_100]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATTCATCTTTACACAAATGTTAATGGAAAACAAAGACAGGTTGA
CCTTTGTCAAAACTGTTACCAAATCATGAAAACAGACCCAACCAATCCTATTTTAGGTGGCCTAAACAGAGGACAAAAAG
CCCAAGATCGGTCTTCACATCCTTTCTTTGATGACTTTTTCGGCGACCTCAATAATTTTAGAGCCTTCGGTAATCTTCCT
AATACACCGCCTACACAAGCGGGCCAAAATGGCAACGGAGGAGGACGTCACGGTGGCAATTATAATGGGCAAGGGCAAGG
GCAACCACAGCCGCAAGCCCCAAATCAGCAAGCAAAAGGCCTACTAGAAGAATTTGGCATTAACGTGACCGATATTGCAA
GGCATGGCGATATTGACCCTGTTATCGGCCGTGATGAGGAAATCACCCGTGTGATTGAAATCCTCAATCGCCGAACCAAA
AATAATCCTGTGCTTATTGGTGAGCCAGGAGTTGGTAAAACTGCTGTTGTAGAAGGTTTGGCTCAAAAAATTGTTGATGG
TACTGTTCCTCATAAATTGCAGGGCAAACAAGTTATCCGTCTTGATGTGGTTAGTCTTGTTCAGGGAACAGGTATCCGTG
GTCAATTTGAAGAGCGCATGCAGAAATTAATGGAAGAAATTCGCAATCGCAAGGAGGTCATTCTCTTCATTGATGAAATT
CATGAGATTGTCGGTGCCGGTTCTGCTGGCGATGGCAATATGGATGCTGGTAATATTTTAAAACCAGCCTTAGCCCGTGG
TGAATTGCAGCTCGTCGGTGCTACCACCTTAAATGAATACCGTATTATTGAAAAAGATGCCGCCTTAGAACGACGCATGC
AGCCGGTGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACGATTTTAAAAGGTATCCAACCCAAATACGAAGACTAC
CATCATGTCAAATATAGCCCAGCTGCTATTGAAGCTGCCGCTCATTTATCCAACCGCTATATTCAAGACCGTTTTCTTCC
AGATAAGGCTATTGACCTCTTGGACGAAGCTGGTTCCAAAATAAATTTAACCCTCAACTTTGTTGATCCGAAAGAGATTG
ACAAACGCCTTATTGAAGCAGAAAATCTCAAAGCCCAAGCTACTCGAGACGAAGACTATGAACGCGCCGCTTATTTCCGC
GATCAAATTGCAAAATACAAAGAAATGCAGGCTCAAAAAGTCAATGAGCAAGATATTCCAATCATTACTGAAAAAAACAT
TGAAGCTATTGTAGAGCAAAAAACTAATATTCCAGTTGGAGACTTGAAAGAAAAAGAACAGTCTCAACTTGTAAATTTAG
CCAACGATCTAAAAGCACACGTGATTGGACAAGACGCTGCTGTTGATAAAATTGCTAAGGCTATTCGTCGTAACCGCGTG
GGACTTGGTACGCCAAATCGTCCAATCGGTTCCTTCCTTTTTGTTGGACCGACTGGGGTCGGTAAAACGGAATTGTCTAA
ACAGCTGGCTATTGAACTCTTTGGCTCGGCAGACAACATGATTCGCTTTGACATGTCCGAATACATGGAAAAACACGCTG
TCGCCAAATTAGTCGGAGCACCTCCAGGTTATGTCGGTTATGAAGAAGCCGGACAGTTAACCGAACAAGTTCGTCGCAAT
CCGTATTCCCTTATTCTCTTAGATGAGGTGGAGAAAGCCCATCCTGACGTCATGCACATGTTCTTGCAAGTTCTTGATGA
TGGCCGTTTAACAGATGGTCAAGGACGAACAGTCAGCTTCAAGGACACCATTATTATCATGACTTCCAATGCCGGAACAG
GCAAAACCGAGGCCTCAGTTGGCTTTGGTGCGGCTAGAGAAGGACGGACAAATTCTGTTCTAGGTGAATTAAGCAACTTC
TTCAGCCCAGAATTCATGAACCGTTTTGATGGTATTATCGAATTTAAGGCCTTGAGCAAGGATAACCTCCTACACATCGT
TGATTTAATGTTAGCTGATGTTAATCAACGCTTAGCTTACAATAATATCGACCTAGATGTGACACAAAAGGTCAAAGAAA
AATTAGTTGACCTAGGCTATGATCCTAAAATGGGCGCTCGACCTCTTCGTCGCACCATTCAAGATTACATTGAAGATGCT
ATTACAGACTACTATTTAGAACATCCAACTGAAAAAGACTTGCGTGCCGTTATGACAAGCAATGGGAACATTATGATTAA
AGCCGCTAAAAAAGGGGAAACCGTTCCTACTACCCAAGAACAGGACAACAATCATTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(302-399)

ATPase family associated with various cellular activities (AAA) (AAA)

(164-283)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(658-732)

AAA domain (Cdc48 subfamily) (AAA_2)

(487-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.469

98.954

0.846
  clpE Streptococcus pneumoniae Rx1

83.574

99.477

0.831
  clpE Streptococcus pneumoniae D39

83.574

99.477

0.831
  clpE Streptococcus pneumoniae R6

83.574

99.477

0.831
  clpE Streptococcus pneumoniae TIGR4

83.443

99.477

0.83
  clpC Lactococcus lactis subsp. cremoris KW2

74.248

100

0.742
  clpC Bacillus subtilis subsp. subtilis str. 168

51.149

85.359

0.437
  clpC Streptococcus pneumoniae D39

47.476

82.876

0.393
  clpC Streptococcus pneumoniae Rx1

47.476

82.876

0.393
  clpC Streptococcus pneumoniae TIGR4

47.319

82.876

0.392
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.429

84.183

0.391
  clpC Streptococcus mutans UA159

47.665

81.176

0.387
  clpC Streptococcus thermophilus LMD-9

46.795

81.569

0.382
  clpC Streptococcus thermophilus LMG 18311

46.474

81.569

0.379

Multiple sequence alignment