Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GFX43_RS05895 Genome accession   NZ_CP046448
Coordinates   1157988..1158632 (+) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain ZD01     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1152988..1163632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFX43_RS05870 (GFX43_005870) - 1153403..1153771 (-) 369 WP_015483634.1 hypothetical protein -
  GFX43_RS20655 - 1153949..1154011 (-) 63 Protein_1141 hypothetical protein -
  GFX43_RS05875 (GFX43_005875) degQ 1154233..1154373 (+) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  GFX43_RS05880 (GFX43_005880) - 1154558..1155418 (+) 861 WP_015483633.1 polyprenyl synthetase family protein -
  GFX43_RS05885 (GFX43_005885) comX 1155431..1155595 (+) 165 WP_015384519.1 competence pheromone ComX -
  GFX43_RS05890 (GFX43_005890) comP 1155607..1157907 (+) 2301 WP_046340263.1 histidine kinase Regulator
  GFX43_RS05895 (GFX43_005895) comA 1157988..1158632 (+) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  GFX43_RS05900 (GFX43_005900) yuxO 1158650..1159030 (+) 381 WP_015483631.1 hotdog fold thioesterase -
  GFX43_RS05905 (GFX43_005905) mnhG 1159069..1159443 (-) 375 WP_014477830.1 monovalent cation/H(+) antiporter subunit G -
  GFX43_RS05910 (GFX43_005910) mrpF 1159427..1159711 (-) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  GFX43_RS05915 (GFX43_005915) mrpE 1159711..1160187 (-) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  GFX43_RS05920 (GFX43_005920) mrpD 1160193..1161674 (-) 1482 WP_015384516.1 Na+/H+ antiporter subunit D -
  GFX43_RS05925 (GFX43_005925) mrpC 1161667..1162008 (-) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  GFX43_RS05930 (GFX43_005930) mrpB 1162008..1162439 (-) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=404380 GFX43_RS05895 WP_003220716.1 1157988..1158632(+) (comA) [Bacillus subtilis strain ZD01]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=404380 GFX43_RS05895 WP_003220716.1 1157988..1158632(+) (comA) [Bacillus subtilis strain ZD01]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATCT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATTTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCCCGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment