Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   HWU19_RS06645 Genome accession   NZ_CP058251
Coordinates   1395093..1396301 (+) Length   402 a.a.
NCBI ID   WP_237016384.1    Uniprot ID   -
Organism   Helicobacter pylori strain UBN18     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1390093..1401301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWU19_RS06630 - 1392175..1392315 (+) 141 WP_000789926.1 hypothetical protein -
  HWU19_RS06635 - 1392308..1393444 (+) 1137 WP_000067684.1 VirB8/TrbF family protein -
  HWU19_RS06640 - 1393441..1395096 (+) 1656 WP_033758819.1 TrbG/VirB9 family P-type conjugative transfer protein -
  HWU19_RS06645 comB10 1395093..1396301 (+) 1209 WP_237016384.1 DNA type IV secretion system protein ComB10 Machinery gene
  HWU19_RS06650 - 1396285..1398525 (+) 2241 WP_237016385.1 collagen-like protein -
  HWU19_RS06655 - 1398538..1399515 (+) 978 WP_237016386.1 hypothetical protein -
  HWU19_RS06660 - 1399532..1399807 (+) 276 WP_001278752.1 hypothetical protein -
  HWU19_RS06665 - 1399812..1400756 (+) 945 WP_140575238.1 CpaF/VirB11 family protein -
  HWU19_RS06670 - 1400753..1401271 (+) 519 WP_100973850.1 replication regulatory RepB family protein -

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 44929.45 Da        Isoelectric Point: 9.9996

>NTDB_id=404233 HWU19_RS06645 WP_237016384.1 1395093..1396301(+) (comB10) [Helicobacter pylori strain UBN18]
MKQSLLKKIGLGVGGFVVLIALGLLANKGSNNNNKEEIFQVSESKFPLSDYFFEEVKEEPKEKAKETPEVTTQEPTTQTS
PNPSVSANPNIKDYSHLNSNLNQQNNTITHLQQVLQSPSKINPKPKHTKEQLEFLNTRLKPLEPTKPATKPETEYGVDSF
TNLKYKDIGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFASMGRAVLIPKGSKVIGYYNNNNQIGQYRL
NIAWTRIITPQGINIMLTNARGADVKGYNGLVGKYISRNFQRYGIPLLTNTLSNGLLIGITSALANRQNRKGDGNPFFGD
YLLMQLTRNTGMGINQVINQMLRQYGAQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPPIKTKEEINNEE
EI

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=404233 HWU19_RS06645 WP_237016384.1 1395093..1396301(+) (comB10) [Helicobacter pylori strain UBN18]
ATGAAACAATCCTTGCTTAAAAAGATAGGCTTAGGTGTTGGGGGCTTTGTTGTTTTAATAGCATTAGGATTGCTTGCTAA
TAAAGGCTCAAACAATAACAATAAAGAAGAAATCTTTCAAGTAAGTGAGAGTAAATTCCCTTTAAGTGATTATTTCTTTG
AAGAAGTCAAAGAAGAGCCAAAAGAAAAAGCCAAAGAAACACCAGAAGTAACTACCCAAGAGCCTACAACACAAACTAGC
CCCAATCCTAGTGTTTCAGCTAATCCTAACATTAAAGATTATAGTCATCTTAACAGCAATCTTAATCAGCAAAATAATAC
TATCACGCATTTGCAACAAGTTTTACAAAGCCCCTCTAAAATAAATCCTAAACCAAAGCATACTAAAGAGCAATTAGAAT
TTTTAAACACACGCCTTAAACCTTTAGAACCAACTAAACCAGCCACTAAGCCTGAGACGGAATACGGCGTGGATAGTTTT
ACTAATTTAAAATATAAAGACATCGGCACTAATGAGCATAAGCTTTTAAGAACCATAACCGCTGATAGAATGATACCAGC
CTTTTTAATCACGCCTATTAGCTCTCAAATTGCTGGAAAAGTAACCGCCCAAGTAGAGAGCGATATATTTGCTTCTATGG
GTAGAGCGGTGCTAATCCCTAAAGGCTCTAAGGTTATAGGCTATTACAATAATAACAATCAAATTGGACAATACCGCCTT
AACATTGCTTGGACTAGAATTATCACGCCTCAAGGCATAAACATCATGCTCACTAACGCAAGGGGGGCTGATGTGAAGGG
TTATAATGGCTTAGTAGGCAAATACATTAGCCGAAACTTTCAACGCTATGGTATCCCCTTACTCACTAACACGCTCTCTA
ATGGTCTTTTAATAGGAATTACTTCAGCCTTAGCTAATAGGCAAAATAGAAAGGGTGATGGCAACCCTTTTTTTGGGGAT
TACTTGCTTATGCAACTCACTAGAAATACAGGCATGGGCATCAATCAAGTTATCAATCAAATGCTAAGGCAATATGGAGC
ACAAAACCCCATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGCCCTAATTTAGACATCTTTATCCCTAAACCAA
AAGATGGGGAGGTTTTAGCGGAGTTCTTTAAAGAGAAAAAACCCCCAATCAAAACAAAAGAGGAAATTAACAATGAAGAA
GAAATCTAA

Domains

Predicted by InterProScan.

Bacterial conjugation TrbI-like protein (TrbI)

(178-368)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

52.538

98.01

0.515

Multiple sequence alignment