Detailed information NTG0404232

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HWU19_RS06625
• Genome accession: NZ_CP058251
• Coordinates: 1389602..1392178 (+)
• Length: 858 a.a.
• NCBI ID: WP_237016383.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain UBN18
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1384602..1397178

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWU19_RS06590	-	1385080..1387023 (-)	1944	WP_237016380.1	site-specific DNA-methyltransferase	-
HWU19_RS06595	-	1387017..1387373 (-)	357	Protein_1285	restriction endonuclease	-
HWU19_RS06600	-	1387428..1388216 (+)	789	WP_237016381.1	integrase	-
HWU19_RS06605	-	1388320..1388799 (+)	480	WP_237016382.1	hypothetical protein	-
HWU19_RS06610	comB2	1388796..1389080 (+)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
HWU19_RS06615	comB3	1389091..1389354 (+)	264	WP_001177711.1	hypothetical protein	Machinery gene
HWU19_RS06620	-	1389366..1389602 (+)	237	WP_140522774.1	hypothetical protein	-
HWU19_RS06625	comB4	1389602..1392178 (+)	2577	WP_237016383.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HWU19_RS06630	-	1392175..1392315 (+)	141	WP_000789926.1	hypothetical protein	-
HWU19_RS06635	-	1392308..1393444 (+)	1137	WP_000067684.1	VirB8/TrbF family protein	-
HWU19_RS06640	-	1393441..1395096 (+)	1656	WP_033758819.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HWU19_RS06645	comB10	1395093..1396301 (+)	1209	WP_237016384.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98646.78 Da
• Isoelectric Point: 8.7648

>NTDB_id=404232 HWU19_RS06625 WP_237016383.1 1389602..1392178(+) (comB4) [Helicobacter pylori strain UBN18]
MLESALKYCKEKAIDLLAGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNIYAKAIITQFESKEIYKTEYFLVFETITSNVKSFFEKKKLEMTTSINEELEES
SKEDKQENENSSNETHSNTSSKKDKKNKFKKKITFSATSKRALLIQTIERVKNALKEFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFVIEFQNQNTFCACVGIKAYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKADIDNYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRHQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFNLKEFVNAIVKTNTDILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVLK

Nucleotide

• Length: 2577 bp

>NTDB_id=404232 HWU19_RS06625 WP_237016383.1 1389602..1392178(+) (comB4) [Helicobacter pylori strain UBN18]
ATGTTAGAAAGCGCCCTTAAATATTGCAAGGAAAAAGCCATAGACCTTTTAGCAGGGTTTGTGCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGACTTAGAGGGCTATTTTGATACTAGACAAAATGTTCTCAAC
ACCATTAGTAAAGACATTCAATTAAGAATTGTGGCTAAAAGGCGTAAGGAATTTATCAATCAAAGTCCAAATATTGACAA
TATTTATGCCAAAGCTATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAGTATTTTTTAGTGTTTGAAACTA
TCACTTCTAATGTCAAGTCTTTCTTTGAAAAAAAGAAATTGGAAATGACTACTTCAATTAATGAAGAGTTAGAAGAAAGC
TCTAAAGAAGATAAACAAGAGAATGAAAATAGCTCCAATGAAACTCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CTCTTAAAGAATTTAAACCCACTTTACTAAATTCTAAAGAAGTATTAAATTTCTACGCAGAATACATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAGAAAGATTACTTTGT
CATTGAATTTCAAAATCAAAACACCTTTTGTGCGTGTGTGGGGATTAAGGCTTATGAGAGCGAAGAAATTTCTTCGCTCC
CTATATCTACTCTTTTACACACCCAAATTGAACTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACTAAGAAAAAGCTCACGCTTTCTAAAATAGTAAAAGCTGATATTGATAATTATATAGAATTAGTGCA
AGCCAATCGTTTGAGCATGCAAGAGTGTGCTTTAAACTTAGTTATAAGGGCTAAAAGTAAAGCTAAATTAGACAAGTCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTACAGAAACTATAGGGCTAAAACCATCTTATTTT
TCATTCTTCCCAAATAACGCCAATATCAACCCTAGAATGAGACATCAAACTTCCCAAGTCATAGCATCTTTGATTTTGTT
TGAGAAAAATAATACAGGTTTTAGAGCAAATTCTTGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAATTTTCATAATCAAGAAGTCAAACATAAGGGCGTGTTAGCCCACAATGTCGCACGAGTAGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGTAAAACCACACTCATTAGCTATTTGATGATGAGTGCCTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAATGCTATTGATACAATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCCTTTTAATTTAAAAGAGTTTG
TCAATGCCATTGTTAAAACCAATACAGACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGTCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGACAGAGCCTTAAAAATCAATCGTGGGTTTTTATGCTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATTACTCAAGCTAGAAAGGCTAATGGG
GTCATTGTTCTAGCCTTACAAGACATTAACCAACTAAGCGAAGTGAGAAACGCTCAAAGCTTTATAAAAAATATGGGGCA
ATTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGATAATCT
CATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTTTGATGACAAAAAACACTTAG
AAAAGGTGCTTAAATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.786	97.902	0.458