Detailed information NTG0404154

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: GNY17_RS14895
• Genome accession: NZ_CP046411
• Coordinates: 2901591..2902460 (-)
• Length: 289 a.a.
• NCBI ID: WP_005493974.1
• Uniprot ID: A0A249W3M2
• Organism: Vibrio parahaemolyticus strain 19-021-D1
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2896591..2907460

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GNY17_RS14860 (GNY17_14860)	rpsP	2897653..2897901 (+)	249	WP_005379962.1	30S ribosomal protein S16	-
GNY17_RS14865 (GNY17_14865)	rimM	2897930..2898478 (+)	549	WP_005462552.1	ribosome maturation factor RimM	-
GNY17_RS14870 (GNY17_14870)	trmD	2898506..2899249 (+)	744	WP_005462562.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
GNY17_RS14875 (GNY17_14875)	rplS	2899291..2899644 (+)	354	WP_005462554.1	50S ribosomal protein L19	-
GNY17_RS14880 (GNY17_14880)	yacG	2899945..2900139 (-)	195	WP_005462546.1	DNA gyrase inhibitor YacG	-
GNY17_RS14885 (GNY17_14885)	zapD	2900208..2900948 (-)	741	WP_015297254.1	cell division protein ZapD	-
GNY17_RS14890 (GNY17_14890)	coaE	2900976..2901590 (-)	615	WP_005480887.1	dephospho-CoA kinase	-
GNY17_RS14895 (GNY17_14895)	pilD	2901591..2902460 (-)	870	WP_005493974.1	prepilin peptidase	Machinery gene
GNY17_RS14900 (GNY17_14900)	pilC	2902525..2903748 (-)	1224	WP_005479682.1	type II secretion system F family protein	Machinery gene
GNY17_RS14905 (GNY17_14905)	pilB	2903773..2905458 (-)	1686	WP_025792845.1	type IV-A pilus assembly ATPase PilB	Machinery gene
GNY17_RS14910 (GNY17_14910)	pilA	2905464..2905922 (-)	459	WP_025518565.1	pilin	Machinery gene
GNY17_RS14915 (GNY17_14915)	nadC	2906185..2907072 (-)	888	WP_015297249.1	carboxylating nicotinate-nucleotide diphosphorylase	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32377.43 Da
• Isoelectric Point: 7.1971

>NTDB_id=404154 GNY17_RS14895 WP_005493974.1 2901591..2902460(-) (pilD) [Vibrio parahaemolyticus strain 19-021-D1]
MEVFQYYPWLFVVFASIFGLIVGSFLNVVIYRLPKIMELEWRRECAESFPEYKIKPPQEVLTLSVPRSSCQNCATPIRIR
DNIPVISWLLLKGKCHHCHTAISPRYPLIELLTAACAGFVAYHFGFSYFTVALIFFTFVLIAATFIDLDTMLLPDQLTLP
LTWAGIALALTEISPVSLQDAVIGAIAGYLCLWSVYWGFKLLTGKEGMGYGDFKLLAALGAWLGWQSLPMIILLSSVVGV
IFGLVQLRLQKQGIERAFPFGPYLAIAGWASLIWGDQILSWYFTSILGV

Nucleotide

• Length: 870 bp

>NTDB_id=404154 GNY17_RS14895 WP_005493974.1 2901591..2902460(-) (pilD) [Vibrio parahaemolyticus strain 19-021-D1]
ATGGAAGTGTTCCAGTACTACCCTTGGCTATTCGTGGTGTTTGCCAGTATCTTCGGTTTAATTGTGGGTAGTTTTCTTAA
TGTAGTCATTTATCGGCTACCTAAAATCATGGAATTAGAATGGCGCCGTGAATGCGCCGAATCATTCCCTGAATATAAGA
TTAAGCCACCTCAAGAAGTTTTGACATTAAGCGTGCCTCGCTCTTCGTGCCAAAACTGCGCGACGCCAATTCGTATTCGA
GACAATATTCCTGTAATCAGCTGGCTACTGTTAAAAGGAAAATGCCATCATTGTCATACCGCAATTAGTCCTCGATATCC
GCTGATAGAATTACTCACTGCAGCGTGCGCTGGTTTTGTGGCTTATCATTTCGGCTTTAGCTACTTTACGGTTGCGTTAA
TCTTTTTCACATTTGTCTTAATAGCCGCGACTTTTATCGATCTCGATACTATGCTGCTACCGGACCAATTAACATTACCA
TTAACTTGGGCTGGCATTGCGTTAGCATTAACAGAAATAAGCCCTGTTAGTCTACAAGACGCCGTAATTGGTGCGATTGC
CGGTTATTTGTGTCTTTGGTCAGTATATTGGGGTTTCAAACTGCTTACTGGTAAAGAAGGCATGGGTTACGGTGATTTTA
AATTGCTGGCTGCCCTTGGCGCTTGGCTAGGATGGCAATCATTACCAATGATCATCCTACTTTCTTCCGTCGTCGGTGTG
ATATTCGGGCTCGTTCAGTTACGACTACAAAAACAAGGTATAGAGAGAGCTTTCCCTTTCGGCCCATATTTAGCGATTGC
AGGATGGGCAAGCTTAATCTGGGGCGATCAAATTCTAAGTTGGTACTTCACGTCAATTTTAGGAGTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (135-244)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: A0A249W3M2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	88.927	100	0.889
pilD	Vibrio cholerae strain A1552	73.611	99.654	0.734
pilD	Acinetobacter baumannii D1279779	52.239	92.734	0.484
pilD	Acinetobacter nosocomialis M2	51.866	92.734	0.481
pilD	Neisseria gonorrhoeae MS11	47.101	95.502	0.45