Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HWV68_RS21245 Genome accession   NZ_CP058242
Coordinates   4072290..4072979 (-) Length   229 a.a.
NCBI ID   WP_003243527.1    Uniprot ID   P42421
Organism   Bacillus subtilis strain SP1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4067290..4077979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWV68_RS21225 (HWV68_21220) yxeA 4068195..4068542 (-) 348 WP_003227084.1 YxeA family protein -
  HWV68_RS21230 (HWV68_21225) yxdM 4068556..4070424 (-) 1869 WP_003244410.1 ABC transporter permease YxdM -
  HWV68_RS21235 (HWV68_21230) yxdL 4070399..4071172 (-) 774 WP_003243557.1 ABC transporter ATP-binding protein YxdL -
  HWV68_RS21240 (HWV68_21235) yxdK 4071316..4072293 (-) 978 WP_003243885.1 two-component system sensor histidine kinase YxdK -
  HWV68_RS21245 (HWV68_21240) braR 4072290..4072979 (-) 690 WP_003243527.1 two-component system response regulator YxdJ Regulator
  HWV68_RS21250 (HWV68_21245) iolJ 4073087..4073959 (-) 873 WP_003242766.1 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase -
  HWV68_RS21255 (HWV68_21250) iolI 4073980..4074816 (-) 837 WP_003244546.1 2-keto-myo-inositol isomerase -
  HWV68_RS21260 (HWV68_21255) iolH 4074902..4075771 (-) 870 WP_003243149.1 sugar phosphate isomerase/epimerase -
  HWV68_RS21265 (HWV68_21260) iolG 4075791..4076825 (-) 1035 WP_003244482.1 bifunctional inositol 2-dehydrogenase/D-chiro-inositol 1-dehydrogenase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26600.34 Da        Isoelectric Point: 4.8564

>NTDB_id=404146 HWV68_RS21245 WP_003243527.1 4072290..4072979(-) (braR) [Bacillus subtilis strain SP1]
MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREKPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISA
RSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKES
KLLEVLLERGEKVTSRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRELNAPVSIEAVRGEGYQLRAQS

Nucleotide


Download         Length: 690 bp        

>NTDB_id=404146 HWV68_RS21245 WP_003243527.1 4072290..4072979(-) (braR) [Bacillus subtilis strain SP1]
TTGAATAAAATCATGATTGTGGAAGACAGTGAAGACATTCGCGGACTATTGCAGAATTACCTTGAAAAATACGGATATCA
AACAGTGGTCGCCGCGGATTTTACAGCTGTTCTTGATGTCTTTTTGCGGGAAAAGCCCGATGTGGTGCTGCTTGATATCA
ATTTGCCGGCATATGACGGATATTATTGGTGCCGGCAGATCCGCCAGCACTCCACAAGCCCGATCATCTTTATTTCTGCC
AGAAGCGGGGAAATGGATCAGGTGATGGCGATTGAAAATGGGGGAGACGATTATATCGAAAAACCGTTTTCTTATGATAT
TGTGCTTGCGAAAATCAAAAGCCAGATCCGGAGGGCGTACGGGGAGTACGCCGCAAAGCAGGGAGAGAAAGTGGTTGAAT
ATGCCGGCGTTCAGCTCTTTGTGGAACGGTTTGAACTGCGTTTTCAGGATGAAAAAAGTGAGCTTTCTAAAAAAGAAAGC
AAGCTTTTGGAAGTGCTGCTTGAGCGGGGAGAAAAGGTGACGAGTCGGGACCGTCTCATGGAAAAGACGTGGGACACCGA
CATATTCATCGATGATAATACACTTAACGTGTATATCACGCGGCTCAGAAAAAAACTGCGGGAGCTGAATGCGCCTGTTT
CTATTGAAGCGGTGCGGGGCGAAGGCTACCAGCTGAGGGCGCAGTCATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P42421

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

41.704

97.38

0.406

Multiple sequence alignment