Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HWV68_RS18675 Genome accession   NZ_CP058242
Coordinates   3567428..3568141 (-) Length   237 a.a.
NCBI ID   WP_003244535.1    Uniprot ID   O06978
Organism   Bacillus subtilis strain SP1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3562428..3573141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWV68_RS18655 (HWV68_18650) ghrB 3562572..3563549 (+) 978 WP_010886621.1 bifunctional glyoxylate/hydroxypyruvate reductase B -
  HWV68_RS18660 (HWV68_18655) psdB 3563587..3565527 (-) 1941 WP_003243432.1 lantibiotic ABC transporter permease PsdB -
  HWV68_RS18665 (HWV68_18660) psdA 3565502..3566281 (-) 780 WP_003228167.1 lantibiotic ABC transporter ATP-binding protein PsdA -
  HWV68_RS18670 (HWV68_18665) psdS 3566364..3567434 (-) 1071 WP_003242699.1 two-component sensor histidine kinase PsdS -
  HWV68_RS18675 (HWV68_18670) braR 3567428..3568141 (-) 714 WP_003244535.1 two-component system response regulator PsdR Regulator
  HWV68_RS18680 (HWV68_18675) yvzJ 3568288..3568497 (+) 210 WP_003243327.1 lipoprotein -
  HWV68_RS18685 (HWV68_18680) yvcN 3568533..3569297 (-) 765 WP_009968228.1 arylamine N-acetyltransferase -
  HWV68_RS18690 (HWV68_18685) crh 3569298..3569555 (-) 258 WP_003219835.1 HPr family phosphocarrier protein -
  HWV68_RS18695 (HWV68_18690) whiA 3569579..3570529 (-) 951 WP_003243775.1 DNA-binding protein WhiA -
  HWV68_RS18700 (HWV68_18695) mgfK 3570552..3571505 (-) 954 WP_003244450.1 gluconeogenesis morphogenetic factor -
  HWV68_RS18705 (HWV68_18700) rapZ 3571507..3572394 (-) 888 WP_003243903.1 RNase adapter RapZ -
  HWV68_RS18710 (HWV68_18705) rppI 3572419..3572895 (-) 477 WP_010886622.1 8-oxo-dGTP diphosphatase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27514.39 Da        Isoelectric Point: 4.6062

>NTDB_id=404131 HWV68_RS18675 WP_003244535.1 3567428..3568141(-) (braR) [Bacillus subtilis strain SP1]
MYRILLVEDDERIASLLGGHLQKYGYEVKIAEQLNDIKLEFAEMKPDLVLLDINLPFFDGFYWCRQIRTISNAPIIFISA
RTDELNQVMAIENGGDDYITKPFHLEVVMAKIKSVLRRTYGEYSPSLPQESRIVELGGLTIYPDQNEAEWNSVRILFSQK
EFQLLSIFVREHKKIVSRDELLEALWDDVDFVDDNTLTVNVNRLRRKLENAGLTDCISTIRGQGYQFQVNRKDEAEC

Nucleotide


Download         Length: 714 bp        

>NTDB_id=404131 HWV68_RS18675 WP_003244535.1 3567428..3568141(-) (braR) [Bacillus subtilis strain SP1]
GTGTATCGGATTTTGCTTGTGGAAGATGATGAGCGGATTGCTTCTTTGCTGGGCGGTCATCTTCAAAAATACGGATATGA
AGTGAAAATTGCTGAACAGCTGAATGATATAAAATTGGAATTTGCAGAAATGAAGCCTGATCTTGTGCTGCTTGATATCA
ACCTGCCTTTTTTTGACGGGTTTTATTGGTGCAGGCAAATCCGTACCATTTCCAATGCGCCGATTATCTTTATATCGGCA
CGGACCGATGAGCTGAATCAGGTAATGGCGATTGAAAATGGCGGCGATGATTATATCACAAAGCCGTTCCATCTAGAGGT
AGTGATGGCCAAAATCAAAAGCGTCCTGCGCCGCACATATGGTGAATATTCGCCCTCTTTGCCGCAGGAATCTAGAATAG
TGGAGCTTGGCGGGCTGACGATTTATCCTGATCAGAATGAGGCCGAATGGAACAGCGTCCGGATTTTGTTTTCCCAAAAA
GAATTCCAGCTTCTCTCGATTTTTGTGAGGGAGCATAAAAAAATTGTCTCTCGTGATGAACTATTGGAGGCGTTATGGGA
TGACGTTGATTTTGTCGATGACAATACGTTAACGGTCAATGTCAATCGGCTGCGGAGAAAACTGGAGAATGCAGGACTGA
CAGATTGCATTTCCACAATCAGAGGACAAGGTTATCAATTTCAAGTCAATCGGAAGGATGAAGCGGAATGTTAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O06978

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

45.536

94.515

0.43

Multiple sequence alignment