Detailed information NTG0404111

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: GNT62_RS28180
• Genome accession: NZ_CP046406
• Coordinates: 5865345..5866682 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain SE5458
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5860345..5871682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GNT62_RS28155 (GNT62_28070)	pgeF	5860488..5861216 (-)	729	WP_003094684.1	peptidoglycan editing factor PgeF	-
GNT62_RS28160 (GNT62_28075)	rluD	5861213..5862175 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
GNT62_RS28165 (GNT62_28080)	-	5862321..5863346 (+)	1026	WP_003094687.1	outer membrane protein assembly factor BamD	-
GNT62_RS28170 (GNT62_28085)	-	5863503..5863748 (+)	246	WP_014603563.1	PP0621 family protein	-
GNT62_RS28175 (GNT62_28090)	pilS	5863738..5865330 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
GNT62_RS28180 (GNT62_28095)	pilR	5865345..5866682 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
GNT62_RS28185 (GNT62_28100)	thiO	5866728..5867822 (-)	1095	WP_003094695.1	glycine oxidase ThiO	-
GNT62_RS28190 (GNT62_28105)	-	5867957..5868466 (+)	510	WP_015503652.1	Tfp pilus assembly protein FimT/FimU	-
GNT62_RS28195 (GNT62_28110)	-	5868572..5869078 (+)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
GNT62_RS28200 (GNT62_28115)	pilV	5869069..5869626 (+)	558	WP_003094697.1	type 4a pilus minor pilin PilV	Machinery gene
GNT62_RS28205 (GNT62_28120)	pilW	5869623..5870447 (+)	825	WP_003094698.1	type 4a pilus minor pilin PilW	-
GNT62_RS28210 (GNT62_28125)	pilX	5870444..5871031 (+)	588	WP_003094700.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=404111 GNT62_RS28180 WP_003094694.1 5865345..5866682(+) (pilR) [Pseudomonas aeruginosa strain SE5458]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=404111 GNT62_RS28180 WP_003094694.1 5865345..5866682(+) (pilR) [Pseudomonas aeruginosa strain SE5458]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTAGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384