Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SPYALAB49_RS03750 Genome accession   NC_017596
Coordinates   738491..738967 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes Alab49     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 733491..743967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYALAB49_RS03725 (SPYALAB49_000761) - 733532..734320 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  SPYALAB49_RS03730 (SPYALAB49_000762) - 734360..735466 (+) 1107 WP_014635422.1 FAD-binding oxidoreductase -
  SPYALAB49_RS03735 (SPYALAB49_000763) rfbA 735524..736393 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  SPYALAB49_RS03740 (SPYALAB49_000764) - 736393..736986 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  SPYALAB49_RS03745 (SPYALAB49_000765) rfbB 737230..738270 (+) 1041 WP_014635423.1 dTDP-glucose 4,6-dehydratase -
  SPYALAB49_RS03750 (SPYALAB49_000766) mutX 738491..738967 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  SPYALAB49_RS03755 (SPYALAB49_000767) - 739025..740206 (+) 1182 WP_002990002.1 AI-2E family transporter -
  SPYALAB49_RS03760 (SPYALAB49_000768) - 740196..741443 (+) 1248 WP_002991966.1 tetratricopeptide repeat protein -
  SPYALAB49_RS03765 (SPYALAB49_000769) fbp54 741502..743154 (-) 1653 WP_014635424.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=40394 SPYALAB49_RS03750 WP_002984880.1 738491..738967(+) (mutX) [Streptococcus pyogenes Alab49]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=40394 SPYALAB49_RS03750 WP_002984880.1 738491..738967(+) (mutX) [Streptococcus pyogenes Alab49]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAAATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment