Detailed information NTG0403707

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GL187_RS09595
• Genome accession: NZ_CP046379
• Coordinates: 1881670..1882680 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 563
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1876670..1887680

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL187_RS09570 (GL187_09685)	-	1876723..1877949 (-)	1227	WP_197097759.1	pyridoxal phosphate-dependent aminotransferase	-
GL187_RS09575 (GL187_09690)	-	1878105..1878398 (-)	294	WP_000977366.1	hypothetical protein	-
GL187_RS09580 (GL187_09695)	-	1878561..1879013 (+)	453	WP_000079148.1	universal stress protein	-
GL187_RS09585 (GL187_09700)	-	1879048..1880436 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GL187_RS09590 (GL187_09705)	-	1880502..1881464 (+)	963	WP_001124777.1	asparaginase	-
GL187_RS09595 (GL187_09710)	ccpA	1881670..1882680 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
GL187_RS09600 (GL187_09715)	-	1883105..1883704 (-)	600	WP_000866719.1	response regulator transcription factor	-
GL187_RS09605 (GL187_09720)	-	1883706..1884803 (-)	1098	WP_000893546.1	sensor histidine kinase	-
GL187_RS09610 (GL187_09725)	-	1884803..1885540 (-)	738	WP_000832834.1	ABC transporter permease	-
GL187_RS09615 (GL187_09730)	-	1885542..1886426 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GL187_RS09620 (GL187_09735)	-	1886413..1886607 (-)	195	WP_000820180.1	hypothetical protein	-
GL187_RS09625 (GL187_09740)	-	1886604..1886810 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=403707 GL187_RS09595 WP_000990607.1 1881670..1882680(-) (ccpA) [Streptococcus pneumoniae strain 563]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=403707 GL187_RS09595 WP_000990607.1 1881670..1882680(-) (ccpA) [Streptococcus pneumoniae strain 563]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568