Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   HED12_RS08500 Genome accession   NZ_CP056077
Coordinates   1637621..1640443 (+) Length   940 a.a.
NCBI ID   WP_202791743.1    Uniprot ID   -
Organism   Escherichia coli strain MS1170     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1632621..1645443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HED12_RS08475 (HED12_08460) soxR 1633559..1634023 (-) 465 WP_000412431.1 redox-sensitive transcriptional activator SoxR -
  HED12_RS08480 (HED12_08465) soxS 1634109..1634432 (+) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  HED12_RS08485 (HED12_08470) pdeC 1634468..1636021 (-) 1554 WP_021530927.1 c-di-GMP phosphodiesterase PdeC -
  HED12_RS08490 (HED12_08475) yjcB 1636450..1636731 (+) 282 WP_001298294.1 YjcB family protein -
  HED12_RS08495 (HED12_08480) ssb 1636830..1637366 (-) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  HED12_RS08500 (HED12_08485) uvrA 1637621..1640443 (+) 2823 WP_202791743.1 excinuclease ABC subunit UvrA Machinery gene
  HED12_RS08505 (HED12_08490) yjbR 1640478..1640834 (-) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  HED12_RS08510 (HED12_08495) yjbQ 1640838..1641254 (-) 417 WP_000270369.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  HED12_RS08515 (HED12_08500) aphA 1641365..1642078 (-) 714 WP_001226933.1 acid phosphatase AphA -
  HED12_RS08520 (HED12_08505) - 1642355..1644175 (+) 1821 WP_021513914.1 ATP-binding protein -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103865.50 Da        Isoelectric Point: 6.6065

>NTDB_id=403318 HED12_RS08500 WP_202791743.1 1637621..1640443(+) (uvrA) [Escherichia coli strain MS1170]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADIDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=403318 HED12_RS08500 WP_202791743.1 1637621..1640443(+) (uvrA) [Escherichia coli strain MS1170]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTTAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAGAAGCCGGACGTCGACCATATTGAAGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGCTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTCTGCTGTACGCTCGCGTTGGTGAGCCGCGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGTC
AGATGGTGGATAACGTGCTTTCGCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAATTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAAGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATAGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCCAACTTTGCCTGCCCGATTTGCGGTTACAGTATGCGCGAGCTGGAACCTCGCCT
GTTTTCATTTAACAACCCGGCGGGAGCCTGCCCGACCTGTGACGGTCTTGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAATTGTCGCTGGCTGGCGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGCGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGTCCGTGCGCCAGCTGCGAAGGAACCCGTCTGCGTCGGGAAGCACGCCACGTGTATGTCGAGAATACGCC
GCTGCCCGCCATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCAGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCAGCAGAGACACTTTCCGGCGGTGAAGCCCAGCGTATTCGTCTGGCGAGCCAGATTGGTGCAGGCCTGGTTGG
CGTGATGTACGTGCTGGATGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGCTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGATCATGTGATCGATATC
GGTCCGGGTGCGGGTGTTCACGGCGGTGAAGTCGTCGCGGAAGGTCCGCTGGAAGCAATAATGGCGGTGCCAGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAAGTGCCGAAGAAGCGCGTTCCGGCAAATCCGGAAAAAGTGCTGA
AACTGACAGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTGACGCTGCCGGTGGGTCTGTTTACTTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACACTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGACTGGAACATTTCGACAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCAACCTACACCGGTGTGTTTACGCCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGCTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAGGCCTGTCAGGGCGACGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGACATTTACGTACCGTGCGACCAGTGCAAAGGCAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTCGGGCAGTCCGC
AACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACGCTGT
ATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTAATTGAGCACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCGGA
AGGCGGCAGTGGGGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAACCGTCGCAGAGTGCGAAGCTTCGCATACGGCGC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

UvrA interaction domain (UvrA_inter)

(130-236)

ABC transporter (ABC_tran)

(806-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.37

100

0.576
  uvrA Streptococcus pneumoniae TIGR4

57.37

100

0.576
  uvrA Streptococcus pneumoniae D39

57.37

100

0.576

Multiple sequence alignment