Detailed information
Bioinformatically predicted
Overview
| Name | sepM | Type | Regulator |
| Locus tag | GL185_RS09025 | Genome accession | NZ_CP046357 |
| Coordinates | 1786059..1787096 (+) | Length | 345 a.a. |
| NCBI ID | WP_000727276.1 | Uniprot ID | A0AAQ2ZXI6 |
| Organism | Streptococcus pneumoniae strain 525 | ||
| Function | processing of CSP (predicted from homology) Competence regulation |
||
Genomic Context
Location: 1781059..1792096
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GL185_RS08990 (GL185_09145) | yidC | 1781094..1782020 (-) | 927 | WP_000835948.1 | membrane protein insertase YidC | - |
| GL185_RS08995 (GL185_09150) | - | 1782098..1782376 (-) | 279 | WP_001174613.1 | acylphosphatase | - |
| GL185_RS09000 (GL185_09155) | - | 1782410..1783150 (+) | 741 | WP_000152701.1 | RNA methyltransferase | - |
| GL185_RS09005 (GL185_09160) | - | 1783206..1783889 (+) | 684 | WP_001016913.1 | Bax inhibitor-1/YccA family protein | - |
| GL185_RS09010 (GL185_09165) | asnA | 1784001..1784993 (+) | 993 | WP_000747993.1 | aspartate--ammonia ligase | - |
| GL185_RS09015 (GL185_09170) | rsmD | 1785058..1785597 (+) | 540 | WP_000706962.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD | - |
| GL185_RS09020 (GL185_09175) | coaD | 1785587..1786075 (+) | 489 | WP_001280742.1 | pantetheine-phosphate adenylyltransferase | - |
| GL185_RS09025 (GL185_09180) | sepM | 1786059..1787096 (+) | 1038 | WP_000727276.1 | SepM family pheromone-processing serine protease | Regulator |
| GL185_RS09030 (GL185_09185) | - | 1787154..1787384 (+) | 231 | WP_000250392.1 | DUF1146 family protein | - |
| GL185_RS09035 (GL185_09190) | murA | 1787408..1788691 (+) | 1284 | WP_000358028.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| GL185_RS09040 (GL185_09195) | - | 1788684..1788872 (+) | 189 | WP_001813390.1 | DNA-directed RNA polymerase subunit beta | - |
| GL185_RS09045 (GL185_09200) | endA | 1788911..1789735 (+) | 825 | WP_001036786.1 | DNA-entry nuclease EndA | Machinery gene |
| GL185_RS09050 (GL185_09205) | - | 1790026..1791357 (+) | 1332 | WP_016398203.1 | hemolysin family protein | - |
Sequence
Protein
Download Length: 345 a.a. Molecular weight: 37553.61 Da Isoelectric Point: 5.0724
>NTDB_id=403205 GL185_RS09025 WP_000727276.1 1786059..1787096(+) (sepM) [Streptococcus pneumoniae strain 525]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP
Nucleotide
Download Length: 1038 bp
>NTDB_id=403205 GL185_RS09025 WP_000727276.1 1786059..1787096(+) (sepM) [Streptococcus pneumoniae strain 525]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sepM | Streptococcus mutans UA159 |
59.357 |
99.13 |
0.588 |