Detailed information    

insolico Bioinformatically predicted

Overview

Name   HI0659   Type   Machinery gene
Locus tag   GL185_RS04830 Genome accession   NZ_CP046357
Coordinates   972309..972575 (-) Length   88 a.a.
NCBI ID   WP_001808618.1    Uniprot ID   A0A0E9GZQ4
Organism   Streptococcus pneumoniae strain 525     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 972653..973147 972309..972575 flank 78


Gene organization within MGE regions


Location: 972309..973147
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL185_RS04830 (GL185_04880) HI0659 972309..972575 (-) 267 WP_001808618.1 helix-turn-helix transcriptional regulator Machinery gene
  GL185_RS04835 (GL185_04885) - 972659..973147 (-) 489 Protein_968 IS30 family transposase -

Sequence

Protein


Download         Length: 88 a.a.        Molecular weight: 9622.15 Da        Isoelectric Point: 4.4893

>NTDB_id=403166 GL185_RS04830 WP_001808618.1 972309..972575(-) (HI0659) [Streptococcus pneumoniae strain 525]
MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEVSGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAI
VPLEQGKS

Nucleotide


Download         Length: 267 bp        

>NTDB_id=403166 GL185_RS04830 WP_001808618.1 972309..972575(-) (HI0659) [Streptococcus pneumoniae strain 525]
TTGGAAGGATGTCCATCTGAGCTCTTTAGCAAGGAGGAAATCCTTGAAAGTGATATGCGAGTGGCTATCATGAGCGAGTT
GATTGAGGCTAGGTATGAACAAGGAATCAGTCAGAAAAAGCTGGAAGAAGTCAGTGGAATAAGCCAGCCTGTCATAGCTA
GGATGGAGACAGGAAAGACTAGTCCTCAGTTGGATACAGTCTTAAAAGTCCTAGCCAGTTTAGGAAAGACACTAGCAATC
GTCCCACTTGAACAGGGAAAAAGTTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(29-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E9GZQ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  HI0659 Haemophilus influenzae Rd KW20

61.039

87.5

0.534

Multiple sequence alignment