Detailed information
Bioinformatically predicted
Overview
| Name | sepM | Type | Regulator |
| Locus tag | GL183_RS01520 | Genome accession | NZ_CP046355 |
| Coordinates | 286551..287588 (+) | Length | 345 a.a. |
| NCBI ID | WP_000727276.1 | Uniprot ID | A0AAQ2ZXI6 |
| Organism | Streptococcus pneumoniae strain 475 | ||
| Function | processing of CSP (predicted from homology) Competence regulation |
||
Genomic Context
Location: 281551..292588
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GL183_RS01485 (GL183_01510) | yidC | 281586..282512 (-) | 927 | WP_000835948.1 | membrane protein insertase YidC | - |
| GL183_RS01490 (GL183_01515) | - | 282590..282868 (-) | 279 | WP_001174613.1 | acylphosphatase | - |
| GL183_RS01495 (GL183_01520) | - | 282902..283642 (+) | 741 | WP_000152701.1 | RNA methyltransferase | - |
| GL183_RS01500 (GL183_01525) | - | 283698..284381 (+) | 684 | WP_001016913.1 | Bax inhibitor-1/YccA family protein | - |
| GL183_RS01505 (GL183_01530) | asnA | 284493..285485 (+) | 993 | WP_000747993.1 | aspartate--ammonia ligase | - |
| GL183_RS01510 (GL183_01535) | rsmD | 285550..286089 (+) | 540 | WP_000706962.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD | - |
| GL183_RS01515 (GL183_01540) | coaD | 286079..286567 (+) | 489 | WP_001280742.1 | pantetheine-phosphate adenylyltransferase | - |
| GL183_RS01520 (GL183_01545) | sepM | 286551..287588 (+) | 1038 | WP_000727276.1 | SepM family pheromone-processing serine protease | Regulator |
| GL183_RS01525 (GL183_01550) | - | 287646..287876 (+) | 231 | WP_000250392.1 | DUF1146 family protein | - |
| GL183_RS01530 (GL183_01555) | murA | 287900..289183 (+) | 1284 | WP_000358028.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| GL183_RS01535 (GL183_01560) | - | 289176..289364 (+) | 189 | WP_001813390.1 | DNA-directed RNA polymerase subunit beta | - |
| GL183_RS01540 (GL183_01565) | endA | 289403..290227 (+) | 825 | WP_001036786.1 | DNA-entry nuclease EndA | Machinery gene |
| GL183_RS01545 (GL183_01570) | - | 290518..291849 (+) | 1332 | WP_016398203.1 | hemolysin family protein | - |
Sequence
Protein
Download Length: 345 a.a. Molecular weight: 37553.61 Da Isoelectric Point: 5.0724
>NTDB_id=403018 GL183_RS01520 WP_000727276.1 286551..287588(+) (sepM) [Streptococcus pneumoniae strain 475]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP
Nucleotide
Download Length: 1038 bp
>NTDB_id=403018 GL183_RS01520 WP_000727276.1 286551..287588(+) (sepM) [Streptococcus pneumoniae strain 475]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sepM | Streptococcus mutans UA159 |
59.357 |
99.13 |
0.588 |