Detailed information    

experimental Experimentally validated

Overview

Name   comA   Type   Regulator
Locus tag   SMU_RS08655 Genome accession   NC_004350
Coordinates   1784304..1786489 (+) Length   727 a.a.
NCBI ID   Protein_1681    Uniprot ID   -
Organism   Streptococcus mutans UA159     
Function   transport of ComC   
Competence regulation

Function

Gene inactivation resulted in a mutant deficient in transformability.


Genomic Context

Location: 1779304..1791489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMU_RS08630 (SMU.1889c) - 1781127..1781390 (-) 264 WP_002352361.1 Blp family class II bacteriocin -
  SMU_RS08635 (SMU.1892c) - 1781694..1781879 (-) 186 WP_002263346.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SMU_RS08645 (SMU.1895c) - 1783456..1783617 (-) 162 WP_002263734.1 Blp family class II bacteriocin -
  SMU_RS08650 (SMU.1896c) - 1783662..1783916 (-) 255 WP_002263733.1 Blp family class II bacteriocin -
  SMU_RS08655 (SMU.1898) comA 1784304..1786489 (+) 2186 Protein_1681 peptide cleavage/export ABC transporter Regulator
  SMU_RS08660 (SMU.1900) comB 1786502..1787515 (+) 1014 WP_002263739.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  SMU_RS09965 (SMU.1902c) - 1787777..1787920 (-) 144 WP_002263740.1 hypothetical protein -
  SMU_RS08665 (SMU.1904c) - 1788212..1789234 (-) 1023 WP_002263742.1 thioredoxin family protein -
  SMU_RS08670 (SMU.1905c) - 1789720..1789908 (-) 189 WP_002263743.1 Blp family class II bacteriocin -
  SMU_RS08675 (SMU.1906c) - 1790072..1790284 (-) 213 WP_002263744.1 Blp family class II bacteriocin -
  SMU_RS09970 (SMU.1908c) - 1790689..1790853 (-) 165 WP_002265308.1 hypothetical protein -

Sequence

Protein


Download         Length: 727 a.a.        Molecular weight: Da        Isoelectric Point:

>NTDB_id=403 SMU_RS08655 Protein_1681 1784304..1786489(+) (comA) [Streptococcus mutans UA159]
None

Nucleotide


Download         Length: 2186 bp        

>NTDB_id=403 SMU_RS08655 Protein_1681 1784304..1786489(+) (comA) [Streptococcus mutans UA159]
ATGTTAGATTCCTTCAAATCTGCTTTACAGCAGTTCGCCGCCAGCATACGCTTTAAGTTCAAATCATTACGATCTTATAA
ATATGTTCCGCAGATAGACTCCAGGGATTGTGGGGTCGCTGCCTTAGCTTCCATCGCCAAATATTATGGCTCGGATTATT
CATTAGCTCACTTGCGAGAACTGGCTAAAACCAGCAAGGAAGGTACAACTGCACTTGGTATTGTGGAAGCGGCCAAAAAG
ATGAAATTTGAAACACGCGCTATTAAAGCCGATATGTCTCTCTTTGATGTAGAGGATATTCCTTATCCTTTTATCGTCCA
TATCGTCAAAGATGGCAAGTTGCAGCACTACTACGTTGTCTACGGTCAGGAAAAAGAAAAAGTAATCATTGGCGACCCTG
ATCCTACTGTTAAAATAGCAACACCTGTCCAAATCGCAATTTGCAGAAGAATGGACAGGTGTTGCTATTTTTCTGGCACC
TGAACCTAGTTATGAACCGCATAAAGACGAAAAGAATGGCTTATCTAGTTTTTTCCCTCTTATATTAAAGCAAAAAGCAC
TTCTTAGTTACATTATCATGGCCAGTTTAATGGTGACACTGATTGATATCGCAGGTTCCTATTATCTACTAGGTATTCTG
GATGAATATATCCCTAATCAGCTCATTTCAACACTGGGTATTATCTCTATTGGCTTAATTATCACCTATATCATCCAACA
GATGATGGAGTTTGCCAAAGGTTACTTACTGGTGGTTCTAAGTCAGCGTCTTGTTATTGATGTTATCCTTTCTTATATTA
GACACATCTTTACCCTGCCGATGTCTTTTTTTGCTACAAGAAGAACAGGGGAAATTACCTCACGTTTCTCTGATGCTAAT
TCCATTATTGATGCCGTGGCTTCAACCATTTTTTCTATCTTTTTGGATCTTACCATGCTTATTTTAGTCGGCAGTGTCCT
ATTGATACAAAATGGCAACCTTTTCCTGCTTACACTCATTTCGATTCCTATCTATGCAGTGATTATCTTTGTTTTCATGA
AACCTTTTGAAAAAATGAATCAGGAAATCATGCAGAGCAATTCAATGGTTTCTTCTGCCATCATTGAAGATATCAATGGT
ATTGAAACCATTAAATCTTTAACCAGTGAAACTGCCCGTTATCAAAATATTGACAGTGAATTTGTGGATTATTTGGACAA
ATCTTTCAAACTCCATAAATATGAAACGCTGCAAACATCACTTAAAAAAGGGGCCCAATTGATTCTCAACGTTGTCATTT
TGTGGTGCGGTGCTCAATTGGTTATGTCGGTCGGCCAGCTCATTACTTATAATTCTTTATTAACCTACTTTTCTAATCCT
ATTGAAAATATTATCAACCTGCAAACCAAACTGCAGTCTGCCAGAGTGGCTAATAATCGTTTAAATGAAGTTTATCTTGT
CGAATCAGAATTTAACGATACTGGAACTTTATCAGACAGTGACTTCCTTGCTGGAGATATTACTTTTGAAGACTTATCTT
ATAAGTATGGTTTTGGAAGAGACACTTTATCAGATATTAATTTAAGGATCAAAAAAAATGATAAAGTCAGTATCGTTGGT
GTCAGCGGATCTGGAAAGACCACTCTAGCGAAAATAATTGTTCATTTTTATGACCCTTATAAGGGACATATTCGAATTAA
TGGCAATGACTTAAAAACAATTGACAAAACCACTTTGCGGCAATATATCAATTATCTGCCGCAGCAGGCTTATATCTTTA
GTGGAACTATCTTTGAAAATCTAACATTAGGAGCTAAAGAAGGCATTAGTCAAGCAGATGTTCTAAAGGCTTGTGAAATT
GCTGAAATTCGCTCGGATATAGAACAAATGCCTATGGGCTATCAAACAGAACTCTCTGACGGAGCCGGTCTATCAGGCGG
ACAAAAACAGCGGGTTGCTTTAGCACGTGCACTTTTAACAAAGTCTCCTGTTTTAATTCTTGATGAAGCTACCAGCAGTC
TTGATGTTCTTACTGAGAAAAAAATTATGGATAACCTGCTGCAGATGGCAGACAAGACTGTTGCTCAGTATCTCTCAGCG
GACCGATAGAGTTATTGTTATGGATAAAGGAAAAATTATTGAAGAAGGTACACATAGTGAACTTATTGCAGCAAATGGTT
TTTATCATCACTTATTTAACAAATAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value

References

[1] F C Petersen et al. (2000) Genetic transformation in Streptococcus mutans requires a peptide secretion-like apparatus. Oral Microbiology And Immunology 15(5):329-34. [PMID: 11154426]