Detailed information NTG0402949

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: GLO74_RS01955
• Genome accession: NZ_CP046354
• Coordinates: 358361..359428 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain 310
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 353361..364428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GLO74_RS01940 (GLO74_01960)	amiA3	353884..355863 (+)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator
GLO74_RS01945 (GLO74_01965)	amiC	355930..357426 (+)	1497	WP_000759903.1	ABC transporter permease	Regulator
GLO74_RS01950 (GLO74_01970)	amiD	357426..358352 (+)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
GLO74_RS01955 (GLO74_01975)	amiE	358361..359428 (+)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
GLO74_RS01960 (GLO74_01980)	amiF	359439..360365 (+)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
GLO74_RS01965 (GLO74_01985)	-	360984..361586 (+)	603	WP_024477719.1	ABC transporter substrate-binding protein	-
GLO74_RS01970 (GLO74_01990)	-	361598..362491 (+)	894	WP_024477718.1	ABC transporter permease	-
GLO74_RS01975 (GLO74_01995)	-	362504..363307 (+)	804	WP_024477717.1	ABC transporter ATP-binding protein	-
GLO74_RS01980 (GLO74_02000)	treR	363340..364050 (-)	711	WP_000760673.1	trehalose operon repressor	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=402949 GLO74_RS01955 WP_000159556.1 358361..359428(+) (amiE) [Streptococcus pneumoniae strain 310]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=402949 GLO74_RS01955 WP_000159556.1 358361..359428(+) (amiE) [Streptococcus pneumoniae strain 310]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTGACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541