Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | GLO74_RS00245 | Genome accession | NZ_CP046354 |
| Coordinates | 41502..43934 (+) | Length | 810 a.a. |
| NCBI ID | WP_061714020.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae strain 310 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Genomic Context
Location: 36502..48934
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GLO74_RS00215 (GLO74_00220) | cbpD | 36537..37883 (+) | 1347 | WP_024478004.1 | choline binding-anchored murein hydrolase CbpD | - |
| GLO74_RS00220 (GLO74_00225) | - | 38139..38429 (+) | 291 | WP_000647661.1 | thiamine-binding protein | - |
| GLO74_RS00225 (GLO74_00230) | - | 38392..39150 (+) | 759 | WP_001245132.1 | ABC transporter permease | - |
| GLO74_RS00230 (GLO74_00235) | - | 39188..40195 (+) | 1008 | WP_000754546.1 | ABC transporter substrate-binding protein | - |
| GLO74_RS00235 (GLO74_00240) | - | 40195..40923 (+) | 729 | WP_000136229.1 | ABC transporter ATP-binding protein | - |
| GLO74_RS00240 (GLO74_00245) | - | 41042..41500 (+) | 459 | WP_001211279.1 | CtsR family transcriptional regulator | - |
| GLO74_RS00245 (GLO74_00250) | clpC | 41502..43934 (+) | 2433 | WP_061714020.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| GLO74_RS00250 (GLO74_00260) | rr06 | 44576..45229 (+) | 654 | WP_001024075.1 | two-component system response regulator RR06 | - |
| GLO74_RS00255 (GLO74_00265) | hk06 | 45226..46557 (+) | 1332 | WP_000594663.1 | two-component system sensor histidine kinase HK06 | - |
| GLO74_RS00260 (GLO74_00270) | - | 46652..47179 (+) | 528 | WP_000241929.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
Sequence
Protein
Download Length: 810 a.a. Molecular weight: 90246.00 Da Isoelectric Point: 5.7851
>NTDB_id=402923 GLO74_RS00245 WP_061714020.1 41502..43934(+) (clpC) [Streptococcus pneumoniae strain 310]
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SRRLQVLFDEAEYVASVVHAKVLGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLMTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKIGV
KAGQLKFDIA
MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SRRLQVLFDEAEYVASVVHAKVLGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLMTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS
DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKIGV
KAGQLKFDIA
Nucleotide
Download Length: 2433 bp
>NTDB_id=402923 GLO74_RS00245 WP_061714020.1 41502..43934(+) (clpC) [Streptococcus pneumoniae strain 310]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCTGGACATTTTGGAGCTCGTTATCTAGA
GTCGTGGCACTTGTTGATTGCCATGTCTAATCACAGTTATAGTGTAGCAGGGGCAACTTTAAATGATTATCCGTATGAGA
TGGACCGTTTAGAAGAGGTGGCTTTGGAACTGACTGAAACGGACTATAGCCAGGATGAAACCTTTACGGAATTGCCGTTC
TCCCGTCGTTTGCAGGTTCTTTTTGACGAAGCAGAGTATGTAGCGTCAGTGGTCCATGCTAAGGTGCTAGGGACAGAGCA
CGTCTTCTATGCGATTTTGCATGATGGCAATGCCTTGGCAACTCGTATCTTGGAGAGGGCTGGTTTTTCTTATGAAGACA
AGAAAGATCAGGTCAAGATTGCTGCTCTTCGTCGAAATTTAGAAGAACGGGCAGGCTGGACTCGTGAAGATCTCAAGGCT
TTACGCCAACGCCATCGTACAGTAGCTGACAAGCAAAATTCTATGGCCAATATGATGGGCATGCCGCAGACTCCTAGTGG
TGGTCTCGAGGATTATACGCATGATTTGACAGAGCAAGCGCGTTCTGGCAAGTTAGAACCAGTCATCGGTCGGGACAAGG
AAATCTCACGTATGATTCAAATCTTGAGCCGGAAGACTAAGAACAACCCTGTCTTGGTTGGGGATGCTGGTGTCGGGAAA
ACAGCTCTGGCGCTTGGTCTTGCCCAGCGTATTGCTAGTGGTGACGTGCCTGCGGAAATGGCTAAGATGCGCGTGTTAGA
ACTTGATTTGATGAATGTCGTTGCAGGGACACGCTTCCGTGGTGACTTTGAAGAACGCATGAATAATATCATCAAGGATA
TTGAAGAAGATGGCCAAGTCATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGCGGAATTGATTCGACT
CTGGATGCGGCCAATATCTTGAAACCAGCCTTGGCGCGTGGAACTTTGAGAACGGTTGGTGCCACCACTCAGGAAGAATA
TCAAAAACATATCGAAAAAGATGCGGCTCTTTCTCGTCGTTTCGCTAAAGTGACGATTGAAGAACCAAGTGTGGCAGATA
GTATGACTATTTTACAAGGTTTGAAGGCGACTTATGAGAAACATCACCGTGTACAAATCACAGATGAAGCGGTTGAAACA
GCGGTTAAGATGGCTCATCGTTATTTAACCAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTGGACGAAGCAGCAGC
AACAGTGCAAAATAAGGCAAAGTATGTAAAAGCAGACGATTCAGATTTGAGTCCAGCTGACAAGGCCCTGATGGATGGCA
AGTGGAAACAGGCAGCCCAGCTAATCGCAAAAGAAGAGGAAGTACCTGTCTACAAAGACTTGATGACAGAGTCTGATATT
TTGACCACCTTGAGTCGCTTGTCAGGAATCCCAGTTCAAAAACTGACTCAGACTGACGCTAAGAAATATCTAAATCTTGA
AGCAGAACTCCATAAACGGGTTATCGGTCAAGATCAAGCTGTTTCAAGTATTAGTCGTGCGATTCGCCGTAATCAGTCAG
GAATTCGCAGTCACAAGCGTCCGATCGGTTCCTTTATGTTCCTAGGACCCACAGGTGTCGGTAAGACCGAGTTGGCCAAG
GCTTTGGCAGAAGTTCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTCGCAGC
CAGCCGTCTAAATGGAGCTCCTCCAGGCTATGTGGGTTACGAAGAAGGTGGGGAGTTGACAGAGAAGGTTCGCAATAAAC
CCTATTCCGTTCTCCTCTTTGATGAGGTAGAGAAGGCTCACCCAGATATCTTTAATGTTCTCTTGCAGGTTCTGGATGAC
GGTGTCTTGACAGATAGCAAGGGACGCAAGGTCGATTTTTCAAATACCATTATCATTATGACATCGAATCTAGGTGCGAC
TGCCCTTCGTGATGATAAGACTGTTGGTTTTGGGGCTAAGGATATTCGTTTTGACCAGGAAAATATGGAAAAACGCATGT
TTGAAGAACTGAAAAAAGCTTATAGACCGGAATTCATCAACCGTATTGATGAGAAGGTGGTCTTCCATAGCCTATCTAGT
GACCATATGCAGGAAGTGGTGAAGATTATGGTCAAGCCTTTAGTGGCAAGTTTGGCTGAAAAAGGCATTGACTTGAAATT
ACAAGCTTCAGCTCTGAAATTGTTAGCAAATCAAGGATATGACCCAGAGATGGGAGCTCGCCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAGGACAAGTTGGCAGAACTTCTTCTTAAGGGAGATTTAGTGGCAGGCAGCACACTTAAGATTGGTGTC
AAAGCAGGCCAGTTAAAATTTGATATTGCATAA
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCTGGACATTTTGGAGCTCGTTATCTAGA
GTCGTGGCACTTGTTGATTGCCATGTCTAATCACAGTTATAGTGTAGCAGGGGCAACTTTAAATGATTATCCGTATGAGA
TGGACCGTTTAGAAGAGGTGGCTTTGGAACTGACTGAAACGGACTATAGCCAGGATGAAACCTTTACGGAATTGCCGTTC
TCCCGTCGTTTGCAGGTTCTTTTTGACGAAGCAGAGTATGTAGCGTCAGTGGTCCATGCTAAGGTGCTAGGGACAGAGCA
CGTCTTCTATGCGATTTTGCATGATGGCAATGCCTTGGCAACTCGTATCTTGGAGAGGGCTGGTTTTTCTTATGAAGACA
AGAAAGATCAGGTCAAGATTGCTGCTCTTCGTCGAAATTTAGAAGAACGGGCAGGCTGGACTCGTGAAGATCTCAAGGCT
TTACGCCAACGCCATCGTACAGTAGCTGACAAGCAAAATTCTATGGCCAATATGATGGGCATGCCGCAGACTCCTAGTGG
TGGTCTCGAGGATTATACGCATGATTTGACAGAGCAAGCGCGTTCTGGCAAGTTAGAACCAGTCATCGGTCGGGACAAGG
AAATCTCACGTATGATTCAAATCTTGAGCCGGAAGACTAAGAACAACCCTGTCTTGGTTGGGGATGCTGGTGTCGGGAAA
ACAGCTCTGGCGCTTGGTCTTGCCCAGCGTATTGCTAGTGGTGACGTGCCTGCGGAAATGGCTAAGATGCGCGTGTTAGA
ACTTGATTTGATGAATGTCGTTGCAGGGACACGCTTCCGTGGTGACTTTGAAGAACGCATGAATAATATCATCAAGGATA
TTGAAGAAGATGGCCAAGTCATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGCGGAATTGATTCGACT
CTGGATGCGGCCAATATCTTGAAACCAGCCTTGGCGCGTGGAACTTTGAGAACGGTTGGTGCCACCACTCAGGAAGAATA
TCAAAAACATATCGAAAAAGATGCGGCTCTTTCTCGTCGTTTCGCTAAAGTGACGATTGAAGAACCAAGTGTGGCAGATA
GTATGACTATTTTACAAGGTTTGAAGGCGACTTATGAGAAACATCACCGTGTACAAATCACAGATGAAGCGGTTGAAACA
GCGGTTAAGATGGCTCATCGTTATTTAACCAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTGGACGAAGCAGCAGC
AACAGTGCAAAATAAGGCAAAGTATGTAAAAGCAGACGATTCAGATTTGAGTCCAGCTGACAAGGCCCTGATGGATGGCA
AGTGGAAACAGGCAGCCCAGCTAATCGCAAAAGAAGAGGAAGTACCTGTCTACAAAGACTTGATGACAGAGTCTGATATT
TTGACCACCTTGAGTCGCTTGTCAGGAATCCCAGTTCAAAAACTGACTCAGACTGACGCTAAGAAATATCTAAATCTTGA
AGCAGAACTCCATAAACGGGTTATCGGTCAAGATCAAGCTGTTTCAAGTATTAGTCGTGCGATTCGCCGTAATCAGTCAG
GAATTCGCAGTCACAAGCGTCCGATCGGTTCCTTTATGTTCCTAGGACCCACAGGTGTCGGTAAGACCGAGTTGGCCAAG
GCTTTGGCAGAAGTTCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTCGCAGC
CAGCCGTCTAAATGGAGCTCCTCCAGGCTATGTGGGTTACGAAGAAGGTGGGGAGTTGACAGAGAAGGTTCGCAATAAAC
CCTATTCCGTTCTCCTCTTTGATGAGGTAGAGAAGGCTCACCCAGATATCTTTAATGTTCTCTTGCAGGTTCTGGATGAC
GGTGTCTTGACAGATAGCAAGGGACGCAAGGTCGATTTTTCAAATACCATTATCATTATGACATCGAATCTAGGTGCGAC
TGCCCTTCGTGATGATAAGACTGTTGGTTTTGGGGCTAAGGATATTCGTTTTGACCAGGAAAATATGGAAAAACGCATGT
TTGAAGAACTGAAAAAAGCTTATAGACCGGAATTCATCAACCGTATTGATGAGAAGGTGGTCTTCCATAGCCTATCTAGT
GACCATATGCAGGAAGTGGTGAAGATTATGGTCAAGCCTTTAGTGGCAAGTTTGGCTGAAAAAGGCATTGACTTGAAATT
ACAAGCTTCAGCTCTGAAATTGTTAGCAAATCAAGGATATGACCCAGAGATGGGAGCTCGCCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAGGACAAGTTGGCAGAACTTCTTCTTAAGGGAGATTTAGTGGCAGGCAGCACACTTAAGATTGGTGTC
AAAGCAGGCCAGTTAAAATTTGATATTGCATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae D39 |
99.383 |
100 |
0.994 |
| clpC | Streptococcus pneumoniae TIGR4 |
99.383 |
100 |
0.994 |
| clpC | Streptococcus pneumoniae Rx1 |
99.383 |
100 |
0.994 |
| clpC | Streptococcus mutans UA159 |
66.667 |
100 |
0.669 |
| clpC | Streptococcus thermophilus LMD-9 |
66.093 |
100 |
0.664 |
| clpC | Streptococcus thermophilus LMG 18311 |
65.971 |
100 |
0.663 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.558 |
100 |
0.499 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
45.241 |
99.877 |
0.452 |
| clpE | Streptococcus mutans UA159 |
49.355 |
76.543 |
0.378 |
| clpE | Streptococcus pneumoniae Rx1 |
47.293 |
77.531 |
0.367 |
| clpE | Streptococcus pneumoniae D39 |
47.293 |
77.531 |
0.367 |
| clpE | Streptococcus pneumoniae R6 |
47.293 |
77.531 |
0.367 |
| clpE | Streptococcus pneumoniae TIGR4 |
47.293 |
77.531 |
0.367 |
| clpC | Lactococcus lactis subsp. cremoris KW2 |
46.955 |
77.037 |
0.362 |