Detailed information NTG0402719

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FOB91_RS09990
• Genome accession: NZ_CP046328
• Coordinates: 2066783..2067826 (+)
• Length: 347 a.a.
• NCBI ID: WP_012000130.1
• Uniprot ID: A8AVZ5
• Organism: Streptococcus gordonii strain FDAARGOS_683
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2061783..2072826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB91_RS09955 (FOB91_09955)	-	2062322..2062615 (-)	294	WP_012000123.1	DUF5960 family protein	-
FOB91_RS09960 (FOB91_09960)	-	2062593..2062967 (-)	375	WP_012000124.1	hypothetical protein	-
FOB91_RS09965 (FOB91_09965)	-	2062964..2064379 (-)	1416	WP_012000125.1	Y-family DNA polymerase	-
FOB91_RS09970 (FOB91_09970)	-	2064383..2065060 (-)	678	WP_012000126.1	helix-turn-helix domain-containing protein	-
FOB91_RS09975 (FOB91_09975)	-	2065203..2065691 (+)	489	WP_012000127.1	YcxB family protein	-
FOB91_RS09980 (FOB91_09980)	rsmD	2065764..2066312 (+)	549	WP_172601498.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FOB91_RS09985 (FOB91_09985)	coaD	2066302..2066796 (+)	495	WP_012000129.1	pantetheine-phosphate adenylyltransferase	-
FOB91_RS09990 (FOB91_09990)	sepM	2066783..2067826 (+)	1044	WP_012000130.1	SepM family pheromone-processing serine protease	Regulator
FOB91_RS09995 (FOB91_09995)	-	2067998..2068534 (+)	537	WP_012000131.1	YutD family protein	-
FOB91_RS10000 (FOB91_10000)	rlmN	2068544..2069632 (+)	1089	WP_012000132.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
FOB91_RS10005 (FOB91_10005)	-	2069619..2070158 (+)	540	WP_012000133.1	VanZ family protein	-
FOB91_RS10010 (FOB91_10010)	trpB	2070524..2071705 (+)	1182	WP_002907062.1	tryptophan synthase subunit beta	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38051.60 Da
• Isoelectric Point: 6.1221

>NTDB_id=402719 FOB91_RS09990 WP_012000130.1 2066783..2067826(+) (sepM) [Streptococcus gordonii strain FDAARGOS_683]
MRKISVYKWPIIIFSSLILLVVSLTVPLPYYIEVPGGAEDIRKVLLVDNKEDKEAGAYEFVTVGVQRATFAHLVYAWLTD
FTDIYSAEEMTGGSSDQEFIRINQFYMETSQNMAKYQGLKTAGKDISMKYLGVYVLQVAKDSTFKGILNIADTVTGVNDK
TFDSSEELVKYVNSQKLGDKVKVTYQEDGQEKSATGKIIKLENGKNGIGISLIDRTEVTSNIPIEFTTEGIGGPSAGLMF
SLSIYTQLADPTLRDGRVIAGTGSINRDGEVGDIGGIDKKVVSAAKSGASIFFAPNNPVTKEMKKIDPKAKTNYETAVEA
AKKIKTDMKIVPVKTLQDAIDYLKNNK

Nucleotide

• Length: 1044 bp

>NTDB_id=402719 FOB91_RS09990 WP_012000130.1 2066783..2067826(+) (sepM) [Streptococcus gordonii strain FDAARGOS_683]
ATGAGAAAAATTAGTGTTTATAAATGGCCCATTATCATTTTTTCAAGCTTGATTTTGCTTGTCGTATCTTTGACGGTTCC
TTTACCATACTATATTGAAGTTCCTGGCGGTGCAGAGGATATTCGAAAGGTCTTGCTGGTTGATAATAAGGAAGATAAGG
AAGCTGGGGCTTACGAGTTTGTGACAGTTGGAGTTCAACGAGCAACCTTTGCTCATCTTGTCTATGCGTGGCTGACTGAT
TTCACGGATATCTACTCTGCTGAAGAAATGACTGGTGGATCATCGGACCAAGAATTTATTCGAATCAATCAGTTTTATAT
GGAAACATCCCAAAACATGGCCAAGTATCAAGGTTTGAAAACGGCTGGAAAAGATATTAGCATGAAATATCTGGGCGTCT
ATGTTTTGCAAGTCGCAAAAGATTCGACTTTTAAGGGAATTTTGAATATTGCGGACACGGTAACGGGAGTTAATGACAAG
ACTTTTGACAGTTCAGAAGAATTGGTGAAATATGTTAATTCGCAGAAATTAGGAGATAAGGTTAAGGTCACTTACCAAGA
AGATGGACAAGAAAAATCTGCTACTGGAAAGATTATTAAGCTAGAAAATGGTAAAAACGGAATTGGTATTAGCTTAATTG
ATAGAACAGAAGTTACTAGTAACATTCCAATTGAATTTACTACAGAAGGCATTGGAGGACCTAGTGCGGGTCTCATGTTT
AGCTTGTCAATCTATACACAACTTGCAGATCCAACCTTACGAGATGGACGTGTGATTGCAGGTACCGGAAGTATCAATCG
TGATGGAGAAGTTGGTGATATTGGAGGGATTGATAAGAAAGTCGTCTCAGCTGCTAAAAGTGGTGCCAGCATCTTCTTTG
CTCCCAATAATCCTGTAACAAAAGAAATGAAAAAAATCGATCCAAAAGCAAAGACAAACTATGAAACTGCAGTTGAGGCT
GCTAAAAAGATTAAAACAGATATGAAAATTGTTCCTGTTAAAACCTTACAGGATGCCATTGATTATCTTAAGAACAATAA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A8AVZ5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.983	99.712	0.608