Detailed information NTG0402458

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FOC55_RS10260
• Genome accession: NZ_CP046301
• Coordinates: 2088346..2089380 (+)
• Length: 344 a.a.
• NCBI ID: WP_002450020.1
• Uniprot ID: -
• Organism: Staphylococcus hominis strain FDAARGOS_747
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2083346..2094380

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC55_RS10235 (FOC55_10240)	-	2084039..2085028 (-)	990	WP_065581070.1	FUSC family protein	-
FOC55_RS10240 (FOC55_10245)	map	2085202..2085954 (+)	753	WP_002455125.1	type I methionyl aminopeptidase	-
FOC55_RS10245 (FOC55_10250)	-	2086003..2087013 (-)	1011	WP_049432034.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
FOC55_RS10250 (FOC55_10255)	-	2087241..2087627 (+)	387	WP_002455127.1	hypothetical protein	-
FOC55_RS10255 (FOC55_10260)	liaF	2087648..2088349 (+)	702	WP_049432039.1	cell wall-active antibiotics response protein LiaF	-
FOC55_RS10260 (FOC55_10265)	vraS	2088346..2089380 (+)	1035	WP_002450020.1	sensor histidine kinase	Regulator
FOC55_RS10265 (FOC55_10270)	vraR	2089382..2090011 (+)	630	WP_002450048.1	two-component system response regulator VraR	Regulator
FOC55_RS10270 (FOC55_10275)	-	2090091..2091299 (-)	1209	WP_065581068.1	YihY/virulence factor BrkB family protein	-
FOC55_RS10275 (FOC55_10280)	-	2091391..2091672 (-)	282	WP_002450075.1	hypothetical protein	-
FOC55_RS10280 (FOC55_10285)	-	2091678..2092142 (-)	465	WP_002455129.1	low molecular weight protein-tyrosine-phosphatase	-
FOC55_RS10285 (FOC55_10290)	-	2092284..2092490 (+)	207	WP_002450082.1	DUF1128 domain-containing protein	-
FOC55_RS10290 (FOC55_10295)	-	2092502..2093749 (+)	1248	WP_065581067.1	aminopeptidase	-
FOC55_RS10295 (FOC55_10300)	-	2093782..2094315 (+)	534	WP_002488082.1	acyl-CoA thioesterase	-

Sequence

Protein

• Length: 344 a.a.
• Molecular weight: 39657.23 Da
• Isoelectric Point: 6.3137

>NTDB_id=402458 FOC55_RS10260 WP_002450020.1 2088346..2089380(+) (vraS) [Staphylococcus hominis strain FDAARGOS_747]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSVLAYKINQQNDWIKN
QIEHAIEGETVGINDKNIELYNETIDIYQMLVPLNQELQRLRIKTQNLTNENYNMNDIKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELAPPLNQQIPVLEKMIQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIYDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNHQDYLLLRIQDNGKGFNVDEKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLTKEEG

Nucleotide

• Length: 1035 bp

>NTDB_id=402458 FOC55_RS10260 WP_002450020.1 2088346..2089380(+) (vraS) [Staphylococcus hominis strain FDAARGOS_747]
ATGAATCACTATTTAAGAGCAATAGGATCCATGCTTATTTTAGTGTATAGCATGTTAACTGCGTTTTTATTTATAGATAA
AGTTTTTGTAAATATTATATATTTTCAAGGAATGTTCTATACTCAAATATTTGGTATACCTGTGTTTCTATTTCTTAATT
TAGTGATTATTTTACTTTGTATTATCGTTGGCTCTGTATTAGCTTATAAAATAAATCAGCAAAATGATTGGATAAAGAAT
CAAATTGAACATGCCATTGAAGGCGAAACGGTAGGGATTAATGATAAAAATATAGAACTATATAATGAGACAATTGATAT
TTATCAAATGTTAGTGCCTTTAAATCAAGAATTACAGAGATTAAGAATTAAAACTCAAAATTTAACAAATGAAAACTACA
ATATGAATGACATTAAAGTTAAAAAAATCATAGAAGATGAGCGTCAGCGTTTAGCAAGGGAACTACACGATTCAGTAAGT
CAACAACTTTTCGCAGCAAGTATGATGCTATCAGCGATAAAAGAAACAGAACTAGCACCACCTCTTAATCAACAAATTCC
AGTACTTGAGAAAATGATACAAGAATCTCAATTAGAGATGCGAGCGCTGTTACTACATTTGCGACCTTTAGGACTCAAAG
ATAAATCATTAGGGGAAGGTATTAAAGATTTAGTCATTGATTTACAAAAGAAAGTACCTATGAAAGTCATTTATGATATA
CAAGATTTTAAAGTTCCTAAAGGAATTGAAGATCATCTATTTCGAATTACACAAGAGGCAATTTCAAATACATTAAGACA
TTCTAATGGAACTAAAGTGACAGTAGAATTATTTAATCATCAAGATTATTTATTATTAAGAATTCAGGATAATGGTAAAG
GTTTTAACGTAGATGAAAAAGTAGAACAAAGTTATGGATTGAAAAATATGAGAGAACGTGCATTAGAAATAGGTGCAACG
TTTCATATCGTATCTTTACCAGATTCAGGAACTAGAATAGAGGTAAAAGCACCTTTAACGAAAGAGGAGGGTTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	89.826	100	0.898