Detailed information NTG0402166

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: HUT15_RS16055
• Genome accession: NZ_CP054920
• Coordinates: 3679039..3680163 (+)
• Length: 374 a.a.
• NCBI ID: WP_030404779.1
• Uniprot ID: A0A6B3QRH4
• Organism: Streptomyces sp. NA03103
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3674039..3685163

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUT15_RS16040 (HUT15_16035)	-	3674048..3674878 (+)	831	WP_176154379.1	hypothetical protein	-
HUT15_RS16045 (HUT15_16040)	-	3675172..3676953 (-)	1782	WP_176154381.1	sigma-70 family RNA polymerase sigma factor	-
HUT15_RS16050 (HUT15_16045)	radA/sms	3677548..3678957 (+)	1410	WP_102932190.1	DNA repair protein RadA	Machinery gene
HUT15_RS16055 (HUT15_16050)	disA	3679039..3680163 (+)	1125	WP_030404779.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
HUT15_RS16060 (HUT15_16055)	-	3680184..3681029 (-)	846	WP_176154383.1	hypothetical protein	-
HUT15_RS16065 (HUT15_16060)	-	3681188..3682114 (+)	927	WP_134656200.1	A/G-specific adenine glycosylase	-
HUT15_RS16070 (HUT15_16065)	-	3682413..3682946 (+)	534	WP_003975479.1	SigE family RNA polymerase sigma factor	-
HUT15_RS16075 (HUT15_16070)	-	3682934..3683611 (+)	678	WP_176154385.1	hypothetical protein	-
HUT15_RS16080 (HUT15_16075)	cseB	3683735..3684439 (+)	705	WP_102930763.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40084.82 Da
• Isoelectric Point: 5.0058

>NTDB_id=402166 HUT15_RS16055 WP_030404779.1 3679039..3680163(+) (disA) [Streptomyces sp. NA03103]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=402166 HUT15_RS16055 WP_030404779.1 3679039..3680163(+) (disA) [Streptomyces sp. NA03103]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGTCTGATCGTGC
TGGGCTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCCGACCTGTCGAAGATCCTGCGGGCCGGGGTGCAGCTCCTTCC
GGATCCCACCATTCCGACGGAGGAGACCGGTACGCGGCACCGGACCGCCGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TCGTGTCGGTCTCGCAGTCGATGCGGCTGATCGCGTTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGACTCGGCCGCG
ATCCTGTCCCGGGCCAACCAGGCGCTGGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCGCGCTGCAGTTGGACGAGCTGATCGCC
GGGGTGGAGCCCGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCGGAGCCGACCGCCAAGCGGTCCCGTACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCACGCGGAACTGCTGGAACTGTCGACCGTGGCCCGGGCCCTGGGCTACACCG
GGTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAACACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTGCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A6B3QRH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447