Detailed information NTG0402099

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: HUT18_RS20075
• Genome accession: NZ_CP054918
• Coordinates: 4699002..4700126 (-)
• Length: 374 a.a.
• NCBI ID: WP_176101983.1
• Uniprot ID: -
• Organism: Streptomyces sp. NA04227
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4694002..4705126

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUT18_RS20050 (HUT18_20045)	-	4694595..4695011 (+)	417	WP_176101978.1	hypothetical protein	-
HUT18_RS20055 (HUT18_20050)	-	4695008..4696981 (+)	1974	WP_176101979.1	caspase family protein	-
HUT18_RS20060 (HUT18_20055)	-	4697013..4697168 (-)	156	WP_176101980.1	hypothetical protein	-
HUT18_RS20065 (HUT18_20060)	-	4697520..4698563 (+)	1044	WP_176101981.1	aldo/keto reductase	-
HUT18_RS20070 (HUT18_20065)	-	4698603..4698863 (-)	261	WP_176101982.1	hypothetical protein	-
HUT18_RS20075 (HUT18_20070)	disA	4699002..4700126 (-)	1125	WP_176101983.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
HUT18_RS20080 (HUT18_20075)	radA/sms	4700194..4701603 (-)	1410	WP_176101984.1	DNA repair protein RadA	Machinery gene
HUT18_RS20085 (HUT18_20080)	-	4701916..4703889 (+)	1974	WP_254878718.1	hypothetical protein	-
HUT18_RS20090 (HUT18_20085)	-	4703929..4704726 (-)	798	WP_254879056.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40295.09 Da
• Isoelectric Point: 4.9269

>NTDB_id=402099 HUT18_RS20075 WP_176101983.1 4699002..4700126(-) (disA) [Streptomyces sp. NA04227]
MAANDRAATPGKSGGISAADGLMRASLSAVAPGTGLRDGLERILRGNTGGLIVLGWDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGGIVLDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVSQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPDRELVVRDYVPEPTARRSRTVDEALSELDSLSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=402099 HUT18_RS20075 WP_176101983.1 4699002..4700126(-) (disA) [Streptomyces sp. NA04227]
GTGGCAGCCAACGACCGGGCAGCGACTCCCGGCAAATCCGGCGGGATCTCCGCCGCCGATGGGCTGATGCGTGCCTCGCT
GAGCGCCGTCGCACCGGGCACCGGGCTGCGTGACGGCCTGGAGCGGATCCTCCGGGGCAACACCGGAGGCCTCATCGTGC
TCGGCTGGGACAAGACCGTCGAGTCCATGTGCACCGGCGGTTTCGTCCTCGATGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACATCACCAAGATCCTTCGGGCCGGTGTGCAACTGGTACC
CGACCCGACCATCCCGACCGAGGAGACCGGCACCCGGCACCGCACCGCCGACCGTGTCTCCAAGCAGGTCGGCTTCCCGG
TGGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCCCTCTACGTCGACGGCCAGCGCCGCGTCCTGGAGGACTCCGCCGCG
ATCCTGTCCCGGGCCAACCAGGCCCTGGCCACCCTGGAGCGCTACAAGCTGCGCCTCGACGAGGTCGCGGGCACCCTCTC
CGCCCTGGAGATCGAGGACCTGGTCACGGTCCGCGACGTCACCGCCGTCTCCCAGCGCCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGCTCGGCACCGACGGCCGTCTGCTCGCCCTCCAGCTGGAGGAGCTGATCGCG
GGCGTCGAACCGGACCGCGAACTCGTCGTACGCGACTACGTCCCCGAGCCCACCGCCCGCCGTTCCCGTACGGTCGACGA
GGCCCTGTCCGAGCTGGACTCGCTGAGCCACGCCGAGCTGCTCGAACTGCCCACGGTCGCCCGCGCGTTGGGCTACACGG
GCTCCCCCGAAGCCCTGGACTCGGCGGTCTCCCCGCGCGGCTTCCGCCTCTTGGCGAAGGTCCCGCGCCTGCCCGGCGCC
ATCATCGACCGCCTGGTGGAACACTTCGGCGGCCTGCAGAAGCTCCTCGCCGCCAGCGTCGACGACCTCCAGACGGTCGA
CGGCGTCGGCGAGGCCCGCGCCCGCAGTGTGCGTGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATTCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.243	92.513	0.428