Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SOR_RS06625 Genome accession   NC_015291
Coordinates   1316665..1318923 (+) Length   752 a.a.
NCBI ID   WP_000882484.1    Uniprot ID   F2QEE4
Organism   Streptococcus oralis Uo5     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1311665..1323923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS06595 (SOR_1353) - 1312450..1313223 (-) 774 WP_000673608.1 HAD hydrolase family protein -
  SOR_RS06600 (SOR_1354) - 1313228..1314085 (-) 858 WP_000057233.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  SOR_RS06605 (SOR_1355) - 1314234..1314554 (-) 321 WP_000168533.1 TfoX/Sxy family protein -
  SOR_RS06610 (SOR_1356) - 1314588..1315322 (-) 735 WP_000140925.1 amino acid ABC transporter ATP-binding protein -
  SOR_RS06615 (SOR_1357) - 1315322..1316005 (-) 684 WP_001011622.1 amino acid ABC transporter permease -
  SOR_RS06620 (SOR_1358) - 1316197..1316427 (+) 231 WP_000443577.1 DUF1797 family protein -
  SOR_RS06625 (SOR_1359) clpE 1316665..1318923 (+) 2259 WP_000882484.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SOR_RS06630 (SOR_1360) - 1318966..1319580 (-) 615 WP_000873102.1 GyrI-like domain-containing protein -
  SOR_RS06635 (SOR_1361) - 1319635..1320537 (-) 903 WP_000841079.1 helix-turn-helix transcriptional regulator -
  SOR_RS06640 (SOR_1362) - 1320714..1321166 (+) 453 WP_000013174.1 NUDIX hydrolase -
  SOR_RS06645 (SOR_1363) - 1321225..1321524 (+) 300 WP_000767208.1 DUF1827 family protein -
  SOR_RS06650 (SOR_1364) metK 1321595..1322785 (-) 1191 WP_000003912.1 methionine adenosyltransferase -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83870.25 Da        Isoelectric Point: 5.1217

>NTDB_id=40205 SOR_RS06625 WP_000882484.1 1316665..1318923(+) (clpE) [Streptococcus oralis Uo5]
MLCQNCKINDSTIHLYTNINGQQKQIDLCQNCYKIIKTDPNNTLFKGMTDLNNHDFDPFGDFFNDLNNFKPSSNNVPPTQ
SGGGYGGNGGYGPQNRGSLQTPPSQERGLLEEYGINITEIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGVQKKYEDYHHVKYTDAAIKA
AANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKEMQKN
KVTDQDTPIISEKTIEHIIEQKTNIPVGELKEKEQSQLIHLADDLKAHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKPLSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDFYLENPSEK
TLKAVMTSNGNIQIKSAKKTEKTEEIASEIEE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=40205 SOR_RS06625 WP_000882484.1 1316665..1318923(+) (clpE) [Streptococcus oralis Uo5]
ATGCTCTGTCAAAACTGTAAAATTAACGACTCAACAATTCATCTGTATACCAATATCAATGGACAGCAAAAGCAAATTGA
TCTCTGTCAAAATTGCTATAAAATTATCAAAACAGATCCAAATAATACCCTTTTTAAAGGAATGACTGACTTAAATAATC
ATGACTTTGATCCCTTCGGCGACTTTTTCAATGATTTGAACAATTTCAAACCTTCTTCTAATAACGTCCCTCCAACTCAA
TCTGGTGGGGGATACGGAGGAAACGGTGGTTATGGGCCTCAAAACCGCGGCTCACTTCAAACACCTCCCAGCCAAGAAAG
AGGACTCTTAGAGGAATATGGTATCAATATTACTGAGATTGCTCGTCGGGGAGATATTGACCCTGTTATCGGTCGAGATG
AGGAGATTATCCGCGTTATCGAAATCCTCAACCGTCGAACCAAAAACAATCCTGTCCTTATCGGTGAACCAGGTGTTGGT
AAAACAGCCGTTGTTGAAGGTCTGGCTCAAAAAATCGTTGATGGTGATGTTCCCCATAAACTCCAAGGCAAGCAAGTCAT
CCGTTTGGATGTGGTCAGCCTAGTTCAAGGAACAGGTATCCGAGGCCAATTTGAAGAGCGTATGCAAAAGCTCATGGAAG
AGATACGCAAACGTGAGGATATCATTCTCTTTATCGATGAAATCCATGAAATTGTCGGTGCAGGATCTGCTGGTGATGGC
AATATGGATGCAGGTAATATCCTCAAACCTGCCCTTGCCCGTGGTGAACTGCAATTGGTCGGTGCCACTACTCTCAATGA
ATACCGTATCATTGAAAAAGATGCTGCCCTCGAACGCCGTATGCAGCCTGTCAAGGTAGATGAACCAACTGTCGAAGAAA
CCATTACCATCCTCAAAGGGGTTCAAAAAAAATACGAAGACTACCATCACGTCAAGTACACAGACGCTGCTATCAAAGCT
GCTGCAAATCTTTCCAATCGCTATATCCAAGACCGCTTCTTGCCAGACAAGGCTATTGACCTGTTAGATGAAGCTGGTTC
TAAGATGAACCTGACACTGAACTTTGTTGATCCTAAAGTGATTGATCAGCGTTTAATTGAAGCTGAGAATCTCAAGGCTC
AAGCTACTCGAGAGGAAGACTTTGAAAAGGCTGCCTATTTCCGCGATCAGATTGCCAAGTACAAGGAAATGCAGAAAAAC
AAGGTGACTGACCAGGATACTCCTATCATTAGCGAGAAAACCATTGAGCATATCATTGAGCAGAAAACCAATATCCCTGT
TGGAGAACTCAAAGAAAAAGAACAGTCTCAGCTTATCCATCTAGCAGACGACCTCAAAGCTCATGTCATTGGTCAAGATG
AAGCTGTGGATAAGATTGCCAAGGCTATCCGTCGTAATCGTGTTGGACTTGGAACTCCTAACCGGCCAATCGGAAGCTTC
CTCTTTGTCGGACCAACTGGTGTCGGTAAAACAGAACTTTCCAAACAACTAGCCATTGAGCTCTTTGGCTCTGCTGACAG
CATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGTGTGGCTAAATTAGTCGGTGCCCCTCCAGGTTATGTTG
GCTACGATGAAGCGGGTCAGTTAACGGAAAAAGTTCGTCGCAATCCTTACTCACTCATCCTTCTCGATGAAGTTGAAAAA
GCCCATCCAGATGTGATGCACATGTTCCTTCAAGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACGAACAGTTAG
CTTTAAGGATGCTATCATTATCATGACCTCAAATGCGGGTACTGGTAAGGCCGAAGCCAGCGTTGGTTTTGGGGCAGCTC
GTGAAGGTCGAACCAACTCTGTTCTCGGTGAACTCGGCAACTTCTTTAGTCCAGAGTTTATGAACCGTTTTGATGGCATC
ATCGAATTTAAACCTCTCAGCAAGGACAATCTTCTCCAAATCGTCGAACTCATGCTAGCGGATGTCAACAAACGCCTCTC
TAGCAACAATATCCACCTCGATGTGACAGACAAGGTCAAGGAAAAGTTGGTTGACCTAGGTTATGATCCAAAAATGGGGG
CGCGCCCACTCCGCCGCACCATTCAAGACTATATCGAGGATGCCATCACTGACTTCTACCTTGAAAATCCAAGTGAGAAA
ACCCTCAAGGCAGTTATGACAAGCAATGGCAATATTCAAATCAAATCTGCCAAAAAAACTGAGAAAACAGAAGAGATTGC
TTCTGAAATAGAAGAATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-720)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA lid domain (AAA_lid_9)

(290-387)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QEE4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.892

98.936

0.939
  clpE Streptococcus pneumoniae D39

94.892

98.936

0.939
  clpE Streptococcus pneumoniae R6

94.892

98.936

0.939
  clpE Streptococcus pneumoniae TIGR4

94.758

98.936

0.937
  clpE Streptococcus mutans UA159

83.156

100

0.834
  clpC Lactococcus lactis subsp. cremoris KW2

76.026

100

0.763
  clpC Bacillus subtilis subsp. subtilis str. 168

52.308

86.436

0.452
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.041

87.633

0.412
  clpC Streptococcus mutans UA159

46.334

85.239

0.395
  clpC Streptococcus pneumoniae TIGR4

47.209

83.378

0.394
  clpC Streptococcus pneumoniae Rx1

47.209

83.378

0.394
  clpC Streptococcus pneumoniae D39

47.209

83.378

0.394
  clpC Streptococcus thermophilus LMD-9

46.593

83.91

0.391
  clpC Streptococcus thermophilus LMG 18311

46.349

83.777

0.388

Multiple sequence alignment