Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SOR_RS01320 Genome accession   NC_015291
Coordinates   248777..249601 (+) Length   274 a.a.
NCBI ID   WP_000359004.1    Uniprot ID   F2QGU3
Organism   Streptococcus oralis Uo5     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 243777..254601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS01290 (SOR_0260) asnA 243867..244859 (+) 993 WP_000747999.1 aspartate--ammonia ligase -
  SOR_RS01295 (SOR_0261) rsmD 244924..245463 (+) 540 WP_000706942.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SOR_RS01300 (SOR_0262) coaD 245453..245941 (+) 489 WP_001280762.1 pantetheine-phosphate adenylyltransferase -
  SOR_RS01305 (SOR_0263) sepM 245925..246962 (+) 1038 WP_000730772.1 SepM family pheromone-processing serine protease Regulator
  SOR_RS09870 (SOR_0264) - 247018..247248 (+) 231 WP_002892633.1 DUF1146 family protein -
  SOR_RS01310 (SOR_0265) murA 247272..248555 (+) 1284 WP_000411922.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SOR_RS01315 (SOR_0266) - 248542..248736 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  SOR_RS01320 (SOR_0267) endA 248777..249601 (+) 825 WP_000359004.1 DNA/RNA non-specific endonuclease Machinery gene
  SOR_RS01325 (SOR_0268) - 249737..251068 (+) 1332 WP_000390021.1 hemolysin family protein -
  SOR_RS01335 (SOR_0270) amiA3 251571..253550 (+) 1980 WP_000749708.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29983.71 Da        Isoelectric Point: 9.8219

>NTDB_id=40179 SOR_RS01320 WP_000359004.1 248777..249601(+) (endA) [Streptococcus oralis Uo5]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQSAPNTPRTKVSQKKQASEAPSQELAESVLTESLKNQIKGGLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKIVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVID

Nucleotide


Download         Length: 825 bp        

>NTDB_id=40179 SOR_RS01320 WP_000359004.1 248777..249601(+) (endA) [Streptococcus oralis Uo5]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTACATCAAGCA
GATGCAGTCAGCGCCAAACACCCCTAGAACCAAGGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCCAGTCAGGAGCTAG
CTGAAAGTGTCTTAACCGAGTCGCTCAAAAACCAAATCAAGGGGGGGCTCGAGTGGAATGGAGCAGGGGCCTTCATTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCTAGCAAACCCTATGCGGATAATAAGACAAAGATAGTTGGAAAAGA
AACAGTCCCGACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAAAATCGTGAAGAAACAGGCAACGGCT
CCACCTCTTGGACGCCACCAGGATGGCATCAGGTCAAGAATCTAAAGGGAACCTATACACATGCAGTTGATAGAGGACAC
CTACTGGGCTATGCCTTGATAGGTGGCTTGGATGGTTTTGATGCCTCTACTAGCAACCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCGAACCAAGCACAGGCTGAGGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AAAACAAGAGGGTCCGTTATCGGGTGACGCTCCACTATGCGACAAATGAGGACCTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACAGAAC
AGGTCAAGTAACAGTGATAGATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QGU3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.338

99.27

0.887
  endA Streptococcus pneumoniae D39

89.338

99.27

0.887
  endA Streptococcus pneumoniae R6

89.338

99.27

0.887
  endA Streptococcus pneumoniae TIGR4

89.338

99.27

0.887

Multiple sequence alignment