Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GKO36_RS05770 Genome accession   NZ_CP046145
Coordinates   1134932..1135588 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain PEBA20     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1129932..1140588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKO36_RS05745 (GKO36_05765) oppF 1130462..1131379 (+) 918 WP_014417419.1 oligopeptide ABC transporter ATP-binding protein OppF -
  GKO36_RS05750 (GKO36_05770) - 1131486..1132682 (+) 1197 WP_014417420.1 putative glycoside hydrolase -
  GKO36_RS05755 (GKO36_05775) - 1132791..1133369 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  GKO36_RS05760 (GKO36_05780) spx 1133548..1133943 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  GKO36_RS05765 (GKO36_05785) - 1134000..1134656 (-) 657 WP_014417421.1 TerC family protein -
  GKO36_RS05770 (GKO36_05790) mecA 1134932..1135588 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  GKO36_RS05775 (GKO36_05795) - 1135740..1136900 (+) 1161 WP_014417422.1 competence protein CoiA family protein -
  GKO36_RS05780 (GKO36_05800) pepF 1137128..1138957 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  GKO36_RS05785 - 1138995..1139162 (-) 168 WP_003155026.1 hypothetical protein -
  GKO36_RS05790 (GKO36_05805) spxH 1139449..1140351 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=401616 GKO36_RS05770 WP_003155032.1 1134932..1135588(+) (mecA) [Bacillus velezensis strain PEBA20]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=401616 GKO36_RS05770 WP_003155032.1 1134932..1135588(+) (mecA) [Bacillus velezensis strain PEBA20]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCAAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment