Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SSAL_RS01970 Genome accession   NC_017594
Coordinates   382414..384519 (+) Length   701 a.a.
NCBI ID   WP_013991074.1    Uniprot ID   -
Organism   Streptococcus salivarius 57.I     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 377414..389519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS01935 (Ssal_00417) - 377419..378051 (+) 633 WP_002884372.1 nicotinate-nucleotide adenylyltransferase -
  SSAL_RS01940 (Ssal_00418) yqeK 378048..378638 (+) 591 WP_014632695.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  SSAL_RS01945 (Ssal_00419) rsfS 378661..379014 (+) 354 WP_014632696.1 ribosome silencing factor -
  SSAL_RS01950 (Ssal_00420) - 379219..379959 (+) 741 WP_013991077.1 class I SAM-dependent methyltransferase -
  SSAL_RS01955 (Ssal_00421) - 379965..381056 (+) 1092 WP_013991076.1 nucleotidyltransferase -
  SSAL_RS01960 (Ssal_00422) - 381197..381451 (+) 255 WP_013991075.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  SSAL_RS01965 (Ssal_00423) - 381455..381709 (+) 255 WP_008535398.1 Txe/YoeB family addiction module toxin -
  SSAL_RS01970 (Ssal_00425) clpE 382414..384519 (+) 2106 WP_013991074.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SSAL_RS10315 (Ssal_00426) - 384955..385080 (+) 126 WP_002884447.1 hypothetical protein -
  SSAL_RS01975 (Ssal_00427) - 385098..385706 (+) 609 WP_013991073.1 DUF4230 domain-containing protein -
  SSAL_RS10180 (Ssal_00428) - 386283..386450 (+) 168 WP_014632697.1 hypothetical protein -
  SSAL_RS01985 (Ssal_00429) - 386631..386930 (-) 300 WP_014632698.1 hypothetical protein -
  SSAL_RS01990 (Ssal_00430) - 386927..387346 (-) 420 WP_014632699.1 HIT family protein -
  SSAL_RS01995 (Ssal_00431) pptA 387411..388142 (+) 732 WP_014632700.1 ABC transporter ATP-binding protein Regulator
  SSAL_RS02000 (Ssal_00432) pptB 388139..389176 (+) 1038 WP_045001493.1 ABC transporter permease Regulator

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77334.21 Da        Isoelectric Point: 4.7207

>NTDB_id=40151 SSAL_RS01970 WP_013991074.1 382414..384519(+) (clpE) [Streptococcus salivarius 57.I]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAE

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=40151 SSAL_RS01970 WP_013991074.1 382414..384519(+) (clpE) [Streptococcus salivarius 57.I]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGTATCCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGGGACGCTGGTGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCTC
AAGCTATCGTTAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATCGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGCGATGGCCAAGGCTCTAAAGGTCTTGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AACGCAGCTCTTGCTCGTCGTTTCAATGAAGTTAAGGTTAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCAGTAGATTTCTCTGTCC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAGTCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTTCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGATCTTATGTTGGTTGAAGTTAACAAGACTCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACTTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTGAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(257-351)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.648

100

0.466
  clpC Lactococcus lactis subsp. cremoris KW2

48.706

93.723

0.456
  clpE Streptococcus pneumoniae D39

48.678

91.726

0.447
  clpE Streptococcus pneumoniae R6

48.678

91.726

0.447
  clpE Streptococcus pneumoniae TIGR4

48.678

91.726

0.447
  clpE Streptococcus pneumoniae Rx1

48.678

91.726

0.447
  clpC Bacillus subtilis subsp. subtilis str. 168

45.666

92.154

0.421
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.089

92.867

0.391
  clpC Streptococcus pneumoniae TIGR4

43.087

88.73

0.382
  clpC Streptococcus pneumoniae Rx1

43.087

88.73

0.382
  clpC Streptococcus pneumoniae D39

43.087

88.73

0.382
  clpC Streptococcus thermophilus LMD-9

43.436

88.017

0.382
  clpC Streptococcus thermophilus LMG 18311

42.973

88.302

0.379
  clpC Streptococcus mutans UA159

42.332

89.301

0.378

Multiple sequence alignment