Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GKC27_RS05645 Genome accession   NZ_CP046130
Coordinates   1159862..1160527 (+) Length   221 a.a.
NCBI ID   WP_034619997.1    Uniprot ID   A0AB34QX40
Organism   Bacillus pumilus strain DSM 27     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1154862..1165527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKC27_RS05615 (GKC27_05585) - 1155185..1156273 (+) 1089 WP_095117782.1 ABC transporter ATP-binding protein -
  GKC27_RS05620 (GKC27_05590) - 1156275..1157195 (+) 921 WP_342688328.1 ATP-binding cassette domain-containing protein -
  GKC27_RS05625 (GKC27_05595) - 1157302..1157589 (+) 288 WP_003211706.1 hypothetical protein -
  GKC27_RS05630 (GKC27_05600) - 1157726..1158304 (+) 579 WP_003211910.1 GNAT family N-acetyltransferase -
  GKC27_RS05635 (GKC27_05605) spxA 1158498..1158893 (+) 396 WP_003211421.1 transcriptional regulator SpxA -
  GKC27_RS05640 (GKC27_05610) - 1158934..1159599 (-) 666 WP_003211565.1 TerC family protein -
  GKC27_RS05645 (GKC27_05615) mecA 1159862..1160527 (+) 666 WP_034619997.1 adaptor protein MecA Regulator
  GKC27_RS05650 (GKC27_05620) cls 1160613..1162133 (+) 1521 WP_003212118.1 cardiolipin synthase -
  GKC27_RS05655 (GKC27_05625) - 1162296..1163456 (+) 1161 WP_003211856.1 competence protein CoiA family protein -
  GKC27_RS05660 (GKC27_05630) pepF 1163671..1165497 (+) 1827 WP_003212054.1 oligoendopeptidase F -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 26383.12 Da        Isoelectric Point: 3.9387

>NTDB_id=401431 GKC27_RS05645 WP_034619997.1 1159862..1160527(+) (mecA) [Bacillus pumilus strain DSM 27]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIVVTKAQL
SKDGQKLELPIPEDKKDQTDEESLDALLDDFQKEEQDQEDDNEKDKKLQLQFVLKMDDFEDLIALSQLNMQDFTTSLYSF
ENRYYLYVDFHEDLSDEQVENKLSILLEYAHESVVSIYRLKEYGQLIIEGNALETIQQHFS

Nucleotide


Download         Length: 666 bp        

>NTDB_id=401431 GKC27_RS05645 WP_034619997.1 1159862..1160527(+) (mecA) [Bacillus pumilus strain DSM 27]
ATGGAAATTGAAAGAATTAATGAACATACAGTGAAATTTTATATTTCCTACGGTGATATTGAAGACCGCGGATTTGACCG
TGAAGAGATTTGGTATAATCGTGAACGCAGTGAAGAGCTGTTTTGGGAAGTAATGGACGAAGTGCACGAAGAAGAAGAAT
TTGCAGTTGAGGGACCGCTTTGGATTCAAGTGCAGGCACTTGACAAAGGTCTTGAAATTGTCGTGACGAAAGCCCAACTT
TCTAAAGATGGACAAAAGCTCGAATTGCCGATTCCAGAAGATAAAAAAGATCAAACAGATGAAGAAAGTCTAGACGCACT
GCTTGATGATTTTCAAAAAGAAGAGCAGGATCAAGAAGACGATAATGAGAAGGACAAAAAACTTCAACTTCAATTTGTGT
TGAAAATGGATGACTTTGAAGATTTGATTGCACTTTCTCAATTAAATATGCAGGATTTTACCACAAGTTTATATTCGTTT
GAAAACCGTTATTATCTATATGTTGACTTCCACGAGGATTTGTCAGATGAGCAAGTGGAGAATAAGCTCAGCATTTTGCT
TGAATATGCTCATGAATCAGTGGTCAGCATTTACAGACTGAAAGAATATGGTCAGCTGATTATCGAAGGTAATGCCCTTG
AAACGATTCAACAGCACTTCTCGTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

77.376

100

0.774

Multiple sequence alignment